Travel Medicine Flashcards

1
Q

Travel to malaria area in less than 1 week

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
  1. Atovaquone/Proguanil 250/100mg PO daily
    Start: 2 days before
    End: 1 week after
  2. NVD
    Abdominal pain
    Headache
3. 
Take daily 
Take with food 
Start 2 days before, end 1 week after return frm trip 
Non pharma
  1. CrCl <30
    Pregnancy / Breastfeeding
    Child <5kg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Travel to malaria area in one months time, patient known with epilepsy.

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
  1. Atovaquone/Proguanil 250/100mg PO daily
    Start: 2 days before
    End: 1 week after
  2. NVD
    Abdominal pain
    Headache
3. 
Take daily 
Take with food 
Start 2 days before, end 1 week after return frm trip 
Non pharma
  1. CrCl <30
    Pregnancy / Breastfeeding
    Child <5kg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Travel to malaria area. Known with GAD

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
  1. Atovaquone/Proguanil 250/100mg PO daily
    Start: 2 days before
    End: 1 week after
  2. NVD
    Abdominal pain
    Headache
3. 
Take daily 
Take with food 
Start 2 days before, end 1 week after return frm trip 
Non pharma
  1. CrCl <30
    Pregnancy / Breastfeeding
    Child <5kg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Travel to malaria area in one months time, patient known with psoriasis.

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
  1. Atovaquone/Proguanil 250/100mg PO daily
    Start: 2 days before
    End: 1 week after
  2. NVD
    Abdominal pain
    Headache
3. 
Take daily 
Take with food 
Start 2 days before, end 1 week after return frm trip 
Non pharma
  1. CrCl <30
    Pregnancy / Breastfeeding
    Child <5kg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Travel to malaria area in one months time, patient known with CKD (CrCl < 30).

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
1. 
Hydroxychloroquine
Start treatment 1 - 2 weeks before travel
Load: 400mg PO twice, 6 hours apart. 
then 400mg PO weekly
Until 4 weeks after travels 
  1. GIT: NVD, Bitter taste

Derma: Hair and skin depigmentation, Alopecia

MSK: Myopathy

Optom: Reversible corneal opacity, Photophobia, Retinopathy

NB: Hypoglycemia

Rare: Deafness

3.
Non Pharma
Start 1 - 2 weeks before travel, continue until 4 weeks after travel
Take with food
If DM - test blood glucose more frequently
Retinal toxicity - if take more than 5 years. Screen for retinal changes

  1. Psoriasis
    Epilepsy
    Psych
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Travel to malaria area in one months time, patient is pregnant

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
1. 
Defer travel
Hydroxychloroquine
Start treatment 1 - 2 weeks before travel
Load: 400mg PO twice, 6 hours apart. 
then 400mg PO weekly
Until 4 weeks after travels 
  1. GIT: NVD, Bitter taste

Derma: Hair and skin depigmentation, Alopecia

MSK: Myopathy

Optom: Reversible corneal opacity, Photophobia, Retinopathy

NB: Hypoglycemia

Rare: Deafness

3.
Non Pharma
Start 1 - 2 weeks before travel, continue until 4 weeks after travel
Take with food
If DM - test blood glucose more frequently
Retinal toxicity - if take more than 5 years. Screen for retinal changes

  1. Psoriasis
    Epilepsy
    Psych
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Travel to malaria area in one months time, patient is a child.

  1. Medication name, dose, route and frequency
  2. Side effects
  3. Advice
  4. Contraindications
A
1. 
Defer travel 
Hydroxychloroquine
Start treatment 1 - 2 weeks before travel
Load: 400mg PO twice, 6 hours apart. 
then 400mg PO weekly
Until 4 weeks after travels 
  1. GIT: NVD, Bitter taste

Derma: Hair and skin depigmentation, Alopecia

MSK: Myopathy

Optom: Reversible corneal opacity, Photophobia, Retinopathy

NB: Hypoglycemia

Rare: Deafness

3.
Non Pharma
Start 1 - 2 weeks before travel, continue until 4 weeks after travel
Take with food
If DM - test blood glucose more frequently
Retinal toxicity - if take more than 5 years. Screen for retinal changes

  1. Psoriasis
    Epilepsy
    Psych
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Organisms responsible for Travellers Diarrhoea

A
1. BACTERIA:
EnteroToxigenic E. Coli
EnteroAggregative E. Coli 
Campylobacter
Salmonella
Shigella

Viruses:
Norovirus
Astrovirus
Rotavirus

Protozoa:
Giardia
Cryptosporidium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Prevention of Travellers Diarrhoea:

  1. Non-Pharmacological
  2. Pharmacological
A
  1. “BOIL it, COOK it, PEEL it or FORGET it”
  • Only drink boiled or bottled water
  • Avoid ice in drinks
  • Only eat recently and well cooked food
  • Avoid street vendors
  • Avoid leftover or opened condiments
  • Avoid salads and raw vegetables
  • Only eat fruit if it has been washed in clean water and peeled
  • Regularly wash hand with soap and water
  • Reassess need for PPI
    • Bismuth Subsalicylate

Class: Intestinal adsorbent

SE: Black stools

CI: Anticoagulant or salicylate use, Young kids

  • Vaccine: Dukoral
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Treatment of travellers diarrhoea

A

MILD:
Fluids
Loperamide
Bismuth Subsalicylate

MOD:
Oral Rehydration Therapy 
Loperamide 4mg Stat then 2mg after each loose stool
Antibiotics
- Ciprofloxacin 500mg PO BD x 3 days 
SEVERE: (Dysentery) 
Oral Rehydration Therapy 
Antibiotics
- Ciprofloxacin 500mg PO BD x 3 days 
\+/- Loperamide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How to make ORT

A

Half a teaspoon of salt (2,5ml)
6 teaspoons of sugar (30ml)
in 1L of safe water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Treatment of travellers diarrhoea in a pregnant patient

A

ORT

Loperamide 4mg PO stat the 2mg PO after each loos stool

Azithromycin 1000mg PO single dose

NOT Bismuth or Fluoroquinolone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Non-pharmacological management and advices when travelling to a malaria area

A
  • Bed nets (impregnated with Permethrin)
  • Avoid dusk and dawn activities
  • Clothes covering exposed skin
  • Sleep in screened & air conditioned room
  • Mosquito coils or aerosolised insecticides
  • Insect repellant with DEET
    • DEET 30% (works for 6 hours)
    • Picaridin 20% (works for 8 hours) less greasy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly