Travel Medicine Flashcards
Measles
Mobiliform rash Kopliks spots Cough Coryza Conjunctivitis
Dengue fever
Lower back pain Rash Fever Frontal headache Retro orbital pain Thrombocytopenia
Aegedes aegypti mozzie
Supportive care
Aegedes aegypti mozzie
Dengue
Zika
Chikagunya
Brucellosis is associated with spondylitis
FASTIDIOUS gram -ve organism, infection greatly reduced with pasteurisation of milk.
35% hepatospenomegaly
Toxoplasmosis
Raw meat or cats Optic atrophy Retinal detachment Cataract Posterior uveitis Glaucoma.
A 28-year-old female returns from a trip to Bangladesh with a fever, diarrhoea and rash. She is diagnosed with typhoid fever.
However, she has a 1-month-old infant and wishes to continue to breast feed.
Which of the following antibiotics is the most appropriate therapy for her?
A. Chlorampenicol
B. Cotrimoxazole
C. Gentamicin
D. Ceftriaxone
E. Ciprofloxacin
Ceftriaxone
Typhoid fever is best treated with quinolones, chloramphenicol or cotrimoxazole.
However, with breast feeding chloramphenicol is relatively contraindicated as are quinolones due to potential risk even if small.
Cotrimoxazole is safe in breast feeding except with infants less than 2 months due to possible risk of increased bilirubin.
In pregnancy or children the drug of choice is parenteral ceftriaxone.
Plasmodium knowlesi
Hyperparasitaemia, lifecycle 24 hours, high mortality, Borneo and Malaysia
P Vivax
High rate of chloroquine resistance - need for artmesinin
IV artesunate
Resistance associated with mutation in ‘propellor’ region of kelch protein gene on chromosome 13
C. Diff
Fluoroquinolones
Keflex
Macrolides
Clindamycin
Resistant TB
Resistance to rifampicin more important than isoniazide (because it means will be def resistant to also isoniazid and hence MDR TB)
Leischmania
Nodules - sandfly
VRE
Usually VanB (teicoplanin okay). Linezolid good for both VanA and VanB
