travel medicine Flashcards
Typhoid
salmonella typhi bacteria
typhoid transmission
oral/fecal. lives only in the human intestinal tract and blood
Typhoid symptoms
GI, fever, weakness, intestinal bleeding, Sepicemia and rose spot rash
typhoid vaccines
IM and oral (live virus)
Yellow fever
togavirus (hemorrhagic disease)
Yellow fever transmission
RNA virus in the flavivridae family, transmitted by mosquitoes. Africa and S. America
Yellow fever stages
85% mild FLS, 15% enter a second toxic phase is fatal is 1/2 of cases
Yellow fever vaccine
Live vaccine
Japanese Encephalitis
Mosquito borne flavivirus. Most preventable cause of encephalitis in Asia. RNA virus
Japanese Encephalitis S/S
stiff neck, stupor, encephalitis if in utero abortion of the fetus
Japanese Encephalitis vaccine
Ver cell culture derived
Cholera
rice water diarrhea, vomit, circulatory collapse. Rehydrate
Bioterror goal
kill a few, hurt and scare many more. Induce fear, disrupt society, overt or covert
Bioterror clues
large outbreak, infection is non endemic to region, unusual distribution
Bacteria biological agents
anthrax, plague and tularemia
Viruses
smallpox, viral hemorrhagic fever
Toxins
botulism
Anthrax
gram positive, spores are found in nature and humans are infective by animals
3 forms of anthrax
cutaneous, ingestion, and inhalation(worst)
Anthrax clinical findings
widened mediastinum on CXR, hemorrhagic meningitis and thoracic lymphadenitis
gastrointestinal antrhrax
GI issue, use dox or cipro
small pox
variola virus (face to face or contaminated objects
small pox rash
starts at day 4, most contagious, tongue and mouth. infectious until the scabs form over.
Plague
yersinia pestis, gram negative bacillus
plague transmission
direct contact with rodent or their fleas
types of plague
pneumonic, bubonic and septicemic
Plague S/S
cervical bulbo, brusing gangrene, sepsis and organ failure
Dx plague
IgM antigen detection
plague tx
strepomycin and gentamycin
Botulism
clostridium botulism, flaccid paralysis or CN 9,10,11,12. odorless and tasteless. The MOST neurotoxin known to man
Tularemia
tick and animal naturally. Pneumonic is the most serious form
Tularemia types
skin ulcers, glandular , eye, oropharngeal. Use PCR test and aminoglycide