Trauma, Burns, and Sepsis Flashcards

1
Q

What are SIRS criteria? What is sepsis? What is severe sepsis? What is septic shock? What is MODS?

A

SIRS: Temp > 38 (100.4) or < 36 (96.8), HR > 90, RR > 20 or PaCO2 < 32, WBC > 12k, < 4k or > 10% bands. SEPSIS = SIRS + likely source of infection. SEVERE SEPSIS = SEPSIS + lactic acidosis, SBP < 90 or SBP drop > 40. SEPTIC SHOCK = SEVERE SEPSIS + hypotension despite fluid resuscitation. MODS = SEPTIC SHOCK + 2 organ failure

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2
Q

Indications for intubation

A

Signs of impending airway obstruction: Stridor, hoarseness, use of accessory muscles and respiratory retractions (soft tissues between ribs on inspiration), penetrating trauma to larynx or trachea. Inadequate respiratory effort, GCS < 9 and inability to protect airway

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3
Q

Once you clear the aiway, you find decreased breath sounds. How do you proceed?

A

CXR and pulse-ox

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4
Q

When can you remove a chest tube in a patient with hx of ptx?

A

When the lung is fully inflated and no further apparent air leak

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5
Q

Tx of sucking chest wound

A

Seal w/occlusive dressing and place chest tube elsewhere

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6
Q

When do you insert a second chest tube?

A

Wrong location (subcutaneous tissues) or not functioning properly (air leak or clotted off)

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7
Q

Pt continues to leak air after chest tube for 6 hours with normal functioning tube. What next?

A

Major airway rupture (can also cause pneumomediastinum). Next step is thoracotomy.

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8
Q

Indications for observation of ptx

A

Small, not enlarging, no free fluid in pleural space, asymptomatic and no other injuries (b/c if you need to operate anesthesia has PEEP of 20-40mmHg).

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9
Q

Why do patients with tension ptx present with hypotension?

A

The pleural pressure exceeds venous pressure and compresses venous return to the heart

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10
Q

Trauma patient presents with JVD, hypotension and pentrating chest trauma. Lungs are clear to ausculatation bilaterally. What’s your next step?

A

Pericardiocentesis in the subxiphoid approach followed by emergent pericardial window in the OR to find the cause of bleeding.

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11
Q

Signs of myocardial contusion

A

Arrrhythmias on ECG and elevated cardiac enzymes

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12
Q

Most common cause of hypotension in trauma patients?

A

Hypovolemia

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13
Q

How is the degree of hemorrhage classified as it relates to shock?

A

Note that significant blood must be lost before compensatory physical exam symptoms begin to manifest (increased HR, RR and decreased urine output are the 1st signs, BP, decreased cap refill and mental status changes come later). Signs of adequate re-hydration include adequate urine output (>30cc/hr), improved HR (<100), improved mental status, improved BP, decreased lactic acidosis (base deficit) and normalization of SvO2 (venous O2 saturation)

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14
Q

Next step when a trauma patient in shock fails to respond to resuscitation?

A

Urgent lap or thoracotomy. If there is time to do a central line do it, if there is a ptx, do it on the same side of the ptx.

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15
Q

Pathophysiology of the Cushing reflex

A

Shock -> hypotension -> brain ischemia -> sympathetic outflow to vasoconstrict and increase cerebral perfusion pressure. Bradycardia happens because the vagus nerve is unaffected by the sympathetic outflow and responds to the increased BP by decreasing HR.

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16
Q

Evaluation of a pregnant woman in shock

A

On her right side to avoid IVC compression and hypotension

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17
Q

Reasons to suspect a urethral injury

A

Blood at the meatus, penile/scrotal hematoma and high riding prostate. Confirm w/retrograde cystourethrogram.

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18
Q

When can you clear a patient of a C-spine injury? What do you do if you can’t clear it?

A

No c-spine tenderness or deformities, sensorimotor function intact, radiographs cleared by radiologist, neurologically intact with no distracting pain. If you can’t clear…neuro consult, IV steroids to maximize recovery of damaged nerves and extreme caution if patient needs to be intubated.

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19
Q

A patient in a car accident has priapism, what are you worried about?

A

Fresh spinal cord injury

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20
Q

What merits emergent thoracotomy?

A

> 1500mL blood evacuated at initial tube thoracostomy, > 200mL over 3+ hours or failure of hypotension to resolve after placement of chest tube.

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21
Q

How does management of a gunshot wound to the abdomen differ from a stab wound?

A

Gunshot wounds always merit abdominal exploration for injury to surrounding structures due to the unpredictable path of bullets.

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22
Q

Pt presents with widened mediastinum on AP films after car accident, what is your next step?

A

If stable, PA film to assess widened mediastinum due to transection (no aortic knob etc). Aortic angiography follows as gold standard dx, then proceed to OR. If patient is unstable go straight to the OR.

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23
Q

Types of injuries that require further evaluation despite abscence of signs/symptoms of injury

A

Unprotected trauma (pedestrians, motorcycles, assaults w/objects), High-energy trauma (MVA w/death at scene, high speed, no seat belts) and Patients w/limited physiologic reserve (elderly, immunosuppressed)

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24
Q

Next step in a patient with fractured pelvis and hypotension

A

Check FAST, if negative go to pelvic angiogram and embolization if needed. Definitive surgery with pelvic reduction and external fixation is necessary.

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25
Q

Pt is stable and presents w/splenic laceration on CT. When do you do surgical exploration?

A

Grade IV and V lacerations. In unstable patients you try to balance preserving the spleen with blood transfused and assess need for splenectomy that way.

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26
Q

Dx of ruptured mesentery

A

Difficult to dx on CT, may see leaking bowel…need ex lap

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27
Q

Tx of liver lacerations

A

Ex lap if unstable. Observation is routinely practiced w/stable patients.

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28
Q

Most important step prior to operating on a renal laceration?

A

IV pyelogram to make sure there is another kidney there.

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29
Q

Management of pancreatic transection

A

Debridement and drainage if minor injury, resection of devitalized pancreas and repair of duodenum in complex injuries. Duodenal diversion for severe injuries

30
Q

Tx for duodenal hematomas

A

NPO and TPN 5-7 days while duodenum recovers

31
Q

Next step for traumatic colonic injury found during ex lap

A

Primary repair is safe with low risk injuries. If high risk (hypotensive, major bleeding or significant peritoneal contamination): resection + colostomy

32
Q

Factors the predict low likelihood of post-traumatic neurologic event

A

Neurologically intact, no sx, normal head CT, not unconscious > 5 min and good home situation

33
Q

Initial management of a serious closed head injury

A

Neuro consult and good pulmonary ventilation and tissue perfusion to reduce brain ischemia, edema and herniation: elevate head 30 degrees, PCO2 at 26-28, mannitol slow infusion and phenytoin for seizure prophylaxis. Hyperventilation is only used with signs of impending herniation.

34
Q

Signs of impending brain herniation

A

Ipsilateral blown pupil and contralateral motor deficits

35
Q

Safe alternatives for intubating a patient with basilar skull fx

A

Orogastric tube and endotracheal tube

36
Q

Tx for SIADH

A

To prevent intracellular edema due to extracellular hypotonicity, water restrict and 3% NaCl if sx are severe (200-300mL over 3-4 hours, correcting 1/2 of the Na deficit over 24 hours to prevent central pontine myelinolysis)

37
Q

Tx for diabetes insipidus in a head trauma patient

A

Confirm by measuring urine osmalality before and after administration of ADH. Tx w/subQ vasopressin (ddAVP) or desmopressin and administration of free water.

38
Q

Why warm a trauma patient who presents with hemorrhage?

A

Hypothermia can cause coagulopathy

39
Q

When do you transfuse platelets in a trauma patient

A

When platelet count is < 50,000

40
Q

Blood loss for a patient coming out of the OR

A

Blood mL for mL. 3mL 0.9% NS for 1 mL EBL.

41
Q

Next step if your hypovolemic patient does not have increased urinary output in response to 1-2L saline bolus challenge?

A

CVP to check preload and confirm hypovolemia. If CVP is normal, it could be from low CO, but more likely due to inaccurate measurement due to decreased preload to the LV also and decreased CO. PCWP should be done next if CVP is normal to assess filling pressures in both sides of the heart (low PCWP = hypovolemia, high = left heart failure or overhydration)

42
Q

Normal SVR

A

800-1000. Elevations occur w/cardiogenic shock (due to sympathetic outflow), hypertension, hypovolemic shock and decreased w/septic shock and neurogenic shock due to vasodilation

43
Q

Normal PCWP

A

15

44
Q

Early vs. late sepsis cardiovascular status

A

Early: Fluid sequestraion and venodilation = hypovolemia and decreased cardiac preload -> early decrease in CO and SVR. Middle: once fluid deficit is replaced, low-SVR and high CO occurs. Late: decreased CO and continued decrease in SVR.

45
Q

Dx and tx of neurogenic shock

A

Hypotension with normal pulses are common. PCWP shows low SVR, low PCWP and low CO. Tx w/IVFs and vasoconstrictors (dopamine, phenylephrine or NE)

46
Q

Heart failure seen with AVFs

A

High output. Confirm dx with palpable thrill, audible bruit, Branham’s sign (occlusion of the fistula with direct pressure leads to drop of HR > 10 beats) and duplex u/s or angiogram.

47
Q

Tx for AVFs

A

1st optimize cardiac status to improve heart failure then operate. Get distal and proximal control.

48
Q

Normal MAP

A

75-100

49
Q

Tx of flail chest

A

Manage pain and increase oxygen content to keep alveoli inflated.

50
Q

Vent setting change if patient has high PCO2

A

Pt is underventilated and need to increase vent rate or volume

51
Q

Vent setting change if patient has low PCO2

A

Vent rate is excessive, lower rate so PCO2 is near 40

52
Q

What can you do with the vent to increase PaO2

A

Increase FiO2 or increase PEEP if alveoli are collapsed. Also consider adjusting ET tube if only one lung has atelectasis

53
Q

Negative effects of PEEP in a patient with ARDS

A

When PEEP is high you decrease CO by impairing venous return, you can cause tension pneumothorax and bronchoalveolar injury

54
Q

Injuries that merit emergent neck exploration

A

Zone II injuries (middle of neck) and expanding neck hematomas

55
Q

Next step w/zone I neck injuries

A

If stable, pre-op angiogram to define injury to subclavian, brachial plexus and lung. If unstable go straight to the OR

56
Q

Zone III neck injury next step

A

Pre-op angiogram to check for injury to carotid

57
Q

No firm evidence of injury but +subQ neck emphysema, next step

A

Bronchoscopy or laryngoscopy. If obvious injury go straight to OR.

58
Q

Management of an asymptomatic carotid thrombosis after blunt trauma?

A

Anticoagulation. If pt is symptomatic, tx is controversial.

59
Q

When to transfer to burn center

A

Full thickness > 5%, partial thickness > 20%, age <5 or > 50, inhalation injury, chemical or electrical burns

60
Q

Parkland formula

A

Fluids for burn patients: LR = %BSA burned x weight in kg x 4. Give 1/2 over 1st 8 hours and 1/2 over next 16 hours.

61
Q

Aside from LR, what other fluids do burn patients need?

A

In the 2nd 24 hours, D5W is given to replace evaporated water and maintain Na at 140. 0.5mL plasma/%BSA burned over 8 hours to maintian oncotic pressure.

62
Q

Medical tx for deep burns

A

Silver sulfadiazine, mafenide and povidone-iodine. Change dressings BID.

63
Q

3rd degree burn management

A

Topical steroids, dressing changes BID, debridement of necrotic tissue regularly until split-thickness graft is given. DON’T USE SYSTEMIC ABX BECAUSE THEY BREED RESISTANT ORGANISMS, only use them to clear pre-existing and documented infections.

64
Q

Tx for myoglobinuria in burn patients

A

Increase urine output to 2-3x normal and alkalinize urine

65
Q

Dx of carbon monoxide poisoning in trauma pt. Tx?

A

Dx w/carboxyhgb > 5% in non-smoker or 10% in smoker pt. Give 100% O2 +/- hyperbaric O2 chamber.

66
Q

Dx of methemoglobinemia. Tx?

A

Dx w/chocolate-brown blood appearance, central cyanosis, arrhythmias, seizures, and ABGs. PULSE-OX will be normal bc reader cannot differentiate between the two type of hgb. Tx with supplemental O2 for 1-3 days. If patient is deteriorating tx w/hyperbaric oxygen and IV methylene blue or exchange transfusion

67
Q

Nondepleted patients vs depleted vs hypermetabolic

A

Nondepleted = good nutritional status in minor catabolic state. Depleted = malnourished befor surgery. Hypermetabolic = severe stress and hypercatabolic from trauma, sepsis cancer etc. Note that catabolism is greatest in burns followed by sepsis followed by trauma followed by minor surgery

68
Q

Nondepleted pt protein requirements

A

1g/kg/day w/daily calories 20% above normal

69
Q

Hypermetabolic patient protein requirements

A

2g/kg/day w/total calories 50-100% normal

70
Q

Where should calories come from with TPN

A

70% carb 30% fat

71
Q

Bad things about TPN

A

Fatty liver and hyperglycemic, hyperosmolar nonketotic coma

72
Q
A