Trauma Basics and Orthopaedic Infections Flashcards
Three peak times of death following trauma
- 50% first minutes (blood loss OR neuro injury)
- 30% in first days (shock; hypoxia; neuro injury)
- 20% days-weeks (multi-system failure AND infection)
- What is the ‘golden hour’
2. What % of preventable deaths occur during this time
- Period of time when life/limb threatening injuries should be treated in order to decrease mortality
- Estimated 60% of preventable deaths can occur during this time
Airbags in head on collision have been shown to significantly reduce: (4)
- Closed head injury
- Facial fractures
- Thoracoabdominal injuries
- Need for extraction
Primary Survery
Treat greatest threats to life first (pelvic # can be a life threatening intervened on by orthopedic surgeons)
- brief history -> ABCDE’s (Airway-> incl. c-spine control ; Breathing and ventilation ; Circulation -> incl hemorrhage control and resus
- pregnant women should be placed in the left lateral decubitus position to limit positional hypotension
- Secondary Survey
2. Tertiary Survey
Secondary survey=physical examination and updated history ALSO obtain indicated imaging studies
Tertiary survey=repeat physical examination and imaging as indicated when mental status has stabilized
**Note: formal tertiary survey decreases chances of missed orthopedic inury
- Average adult has ______L of circulating blood?
2. Average child 2-10yr old has _______mL/kg blood
- 4.7-5L
- 75-80ml/kg
(eg. 30kg child has 2.2-2.4L blood
Methods of Resuscitation
- Fluid
- Blood options
- Ratio of tranfusion (blood:platelet:plasma)
- crystalloid isotonic solution
- O negative blood (universal donor) ; Type specific blood; Cross-matched
- 1 : 1 : 1
- Most sensitive indicators of adequate resuscitation ?
2. Other indicators of adequate resuscitation? (3)
- serum lactate levels (most sensitive indicator as to whether some circulatory beds remain inadequately perfused; normal < 2.5 mmol/L)
2a. urine output 0.5-1.0 ml/kg/hr (30 cc/hr)
2b. gastric mucosal ph
2c. base deficit (normal -2 to +2)
Risk of viral transmission with allogenic blood transfusion
1. HBV
2. HCV
HIV
- 1 in 205,000
- 1 in 1.8 million
- 1 in 1.9 million
Non-hemorrhagic shock (3)
- Cardiogenic shock (insufficient cardiac output due to pump failure)
- Neurogenic shock = hypotension and relative bradycardia from loss of sympathetic tone following spinal cord injury
- Septic shock
(note: septic shock= systemic vascular resistance is decreased VS. hypovolemic shock = vasc resitance increased)
Damage Control Orthopaedics (DCO)
- definition
- General concept
- definitive treatment delayed until physiology has improved
- Involves staging definitive management to avoid adding trauma to patient during vulnerable period
*** Note: the decision to operate and surgical timing on multiple injured trauma patients remains controversial
Parameters for patients treated with DCO principles
- ISS >40 (without thoracic trauma)
- ISS >20 with thoracic trauma
- GCS of 8 or below
- multiple injuries with severe pelvic/abdominal trauma and hemorrhagic shock
- bilateral femoral fractures
- pulmonary contusion noted on radiographs
- hypothermia <35 degrees C
- head injury with AIS of 3 or greater
- IL-6 values above 500pg/dL
Optimal time of surgery in DCO
- During what period should only life threatening injuries be treated ?
Patient are at increased risk of ARDS and multisystem failure during acute inflammatory window (period from 2 to 5 days characterized by a surge in inflammatory markers)
Optimal time of surgery in DCO
- What injuries should be treated during high-risk period in DCO (7) ?
- unstable pelvic fracture
- compartment syndrome
- fractures with vascular injuries
- unreduced dislocations
- traumatic amputations
- unstable spine fractures
- cauda equina syndrome
- open fractures
DCO: Definitive treatment delayed for:
- __to___ days for pelvic fractures
- within _____ weeks for femur fractures
- within __to__ days for tibita fractures
- 7-10 days
- within 3 weeks
- 7-10 days
Open Fractures
- Timing of surgery
- Classifications (2)
- In the absence of life-threatening injuries, there is NO clinical advantage to performing surgery within 6 hours of injury versus 6-24 hours
- (a) gustillo; (b) Tscherne
Open Fractures
- antibiotic management
a) gustillo I/II
b) gustillo III
c) Farm injuries / heavily OR bowel contamination
d) water
a) 1st gen cephalosporin (or vanc or clinda if allergies)
b) 1st gen cephalosporin + aminoglycoside (eg. gentamicin)
c) as above and ADD high dose penicillin for anaerobic coverage (clostridium)
d) fresh = fluroquinolones (eg. cipro); salt = doxy OR fluroquinolone
Open Fractures: Timing of antibiotics
i. increased infection rate when antibiotics are delayed for more than ____hours from time of injury
ii. continue for _____ after wound closure (_____ in type III)
i. 3hrs
ii. 24hrs after closure (72hrs in type III wounds)
Open Fractures: tentanus
i. two forms of tetanus prophylaxis
ii. guideline for use based on what 3 factors?
i. Forms of tetanus prophylaxis
(1) toxoid dose 0.5 mL, regardless of age
(2) immune globulin dosing
- <5-years-old receive 75 U
- 5-10-years-old receive 125 U
- >10-years-old receive 250 U
ii. Guidelines for tetanus prophylaxis depend on 3 factors
(1) complete or incomplete vaccination history (3 doses)
(2) date of most recent vaccination (last 10 years)
(3) severity of wound
Open Fractures: emergency room management
Principles (5)
- Antibiotics: initiate early IV antibiotics and ADT as indicated
- Control bleeding
- direct pressure
- do not blindly clamp or place tourniquets on damaged extremities - Assessment:
- soft-tissue
- NV exam; +/- ABI (normal>0.9); vasc. sx consult and CT-angio) angiogram is warranted if ABI <0.9
consider saline load test if concern for traumatic arthrotomy (*contorversial) - Dressing:
- remove gross debris from wound, do not remove any bone fragments
- place sterile saline-soaked dressing on wound
- little evidence to support aggressive irrigation or irrigation with antiseptic solution in the ED (can push debris further into wound) - Stabilize
- splint, brace, or traction for temporary stabilization (decreases pain, minimizes soft tissue trauma, and prevents disruption of clots)
Open Fractures
Operating room management
i. Wash and debride principles
i.
- thorough debridement is critical to prevent deep infection; remove FB’s
- expose fracture by recreating mechanism of injury, extend wound proximally and distally in line with extremity
- low pressure is preferred over high pressure pulse lavage
- saline most effective irrigating agent
Rule: 3L of saline are used for each successive Gustilo type (Type I: 3L / Type II: 6L / Type III: 9L) - bony fragments without soft tissue attachments should be removed
Open Fractures
i. Fracture Stabilisation
ii. Ex-Fix pin placement
iii. Staged wash/debride every __to__hrs PRN
i. internal fixation, ext-fix or IMN as indicated
ii. avoid placement of pins in proximity to planned definitive incisions
iii. 24-48hrs
Open Fractures: Soft tissue coverage in trauma
i. Timing - general
ii. Tibial coverage
iii. increased risk of infection after ___ days
iv. VAC dressings
v. ABx beads
i. Early coverage OR closure is ideal.
ii. Flap coverage for open tibial Fx is controversial but <5 days is desired
iii. 7 days
iv. VAC may be used during debridement until definitive coverage
v. for open,dirty wounds (made with methylmethacrylate with heat-stable antibiotic powder)
Open Fractures
Bone loss options (3)
- Masquelet technique
- Distraction osteogenesis
- Vascularized bone flap/transfer
Open Fractures
What is the Masquelet Technique?
two-stage technique:
1st stage: debridement and filling of bone loss with an acrylic spacer
- original technique used external fixator, but new techniques use IM nail;
2nd stage: bone recon; filling with cancellous bone in the space left free (following cement removal) inside the so-called self-induced periosteal membrane
Open Fractures: Complications
- Infection
- NV Injury
- Compartment Syndrome
Trauma Scoring Systems: Glasgow Coma Scale (GCS)
- definition
- Breakdown/scoring
- Pros
- quantifies severity of head injury by measuring CNS function
- Motor 1-6 / Verbal 1-5 / Eye opening 1-4 = total 15
- Brain injury: <9= severe; 9-12 moderate; >/=13 minor - Reliably predicts outcomes for diffuse and local lesions
Injury Severity Scale (ISS)
What is ISS
Anatomical region and assigned number ?
How is it calculated
- First scoring system to be based on anatomic criteria
- Based on 9 anatomical regions [1.head 2.face 3.neck 4.thorax 5.abdo/pelvis 6. spine 7. UL 8. LL 9. External
ISS = sum of squares for the highest AIS grades in the three most severely injured ISS body regions [ISS = A2 + B2 + C2]
Systemic Inflammatory Response Syndrome (SIRS)
A generalized response to trauma characterized by ◾an increase in cytokines
◾an increase in complement
◾an increase in hormones
Variables ◦heart rate > 90 beats/min ◦WCC <4000cells/mm³ OR >12,000 cells/mm³ ◦ RR> 20 or PaCO2< 32mm ◦Temp<36 deg or >38deg
Mangled Extremity Severity Score (MESS)
- utility?
- variable?
◦used to predict necessity of amputation after lower extremity trauma
- skeletal and soft tissue injury (energy/MOI graded 1-4)
- limb ischemia (graded 1-3)
- shock (0-2) with persistent hypotension = 2
- age (<30=0; >50=2)
(>7 = high risk of amputation)