transporters Flashcards

1
Q

AE

A

Push HCO3 out
Bring Cl in from lumen

Gallbladder
Cholangicyte
Electroneuronal uptake

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2
Q

NBC

A

Brings bicarb and Na in brom blood stream

Pancreas

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3
Q

NHE

A

Brings Na in and H+ out to bloodstream (Pancreas)

Takes Na from lumen in exchange for H+ (gall bladder, electroneuronal coupled cell)

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4
Q

CFTR

A

brings Cl to apical to be exchanged for bicarb (pancreas, cholangicyte)

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5
Q

NKCL

A

brings in Na, K, Cl- from basolateral (SI/Colon)

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6
Q

Bile salt export pump

A

Bile acids through caniculus

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7
Q

ABCG5/8

A

Cholesterol through caniculus

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8
Q

Multidrug Resistance Prot. 3

A

phosphatedycholine through caniculus

pumps methylated folic acid + 1 glutamate into circulation

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9
Q

Multidrug resistance associated protein

A

conj bilirubin, conj glutathione

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10
Q

SGLT-1

A

glucose & 2Na+ from apical into cell

villi in SI

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11
Q

Na/K ATPase

A

take 3 Na out for 2K in

villi in SI, electroneuronal Na uptake

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12
Q

ClC2

A

push Cl basolaterally

electroneuronal coupled nacl uptake

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13
Q

ASBT

A

symporter

bring bile salt from term ileum

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14
Q

SMCT

A

short chain fatty acid from colon, ileum

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15
Q

H+ dependenced monocarboxylate transporter

A

SCFA from colon, ileum

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16
Q

epithelial Na channel

A

uniport

electrogenic Na uptake in colon

17
Q

Glutamate carboxypeptidase II

A

breaks off extra glutamates from folic acid

18
Q

Proton couple folate transporter (PCFT, SLC46A1)

A

brings folic acid + 1 glutamate in duodenal/jenunal enterocyte

19
Q

multidrug resistance protein 1

A

pumps B12 into circulation