transporters Flashcards

1
Q

where does the absorption of monosaccharides take place

A

lumen of the small intestine, involves brush border of epithelial cells

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2
Q

monosaccharides are transported through the absorptive cells of the intestine by ________ and ________

A
  • facilitated diffusion

- Na+ dependent facilitated transport (active transport)

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3
Q

in the intestinal epithelial cells SGLT-1 transports _______ and _____

A
  • glucose

- galactose

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4
Q

in the kidney, _______ reabsorbs glucose by a _______ dependent glucose transporter

A
  • SGLT-2

- sodium

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5
Q

in facilitated diffusion, monosaccharide transport follows a concentration gradient _______ the use of ATP

A

without

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6
Q

all ______ are transported from the intestinal epithelial cells into the portal of circulation by ______

A
  • monosaccharides

- GLUT-2

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7
Q

tissue distribution of GLUT-1

A
  • red blood cells

- blood brain barriers

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8
Q

tissue distribution of GLUT-2

A
  • liver
  • pancreatic beta cells
  • contraluminal membrane of intestinal epithelial cells
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9
Q

tissue distribution of GLUT-3

A

brain (neurons

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10
Q

tissue distribution of GLUT-4

A
  • adipose tissue
  • skeletal muscle
  • heart muscle
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11
Q

tissue distribution of GLUT-5

A
  • intestinal epithelial cells
  • sperm
  • fructose transporter
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12
Q

which GLUT is insulin sensitive

A

GLUT-4

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13
Q

which GLUT accepts all 3 monosaccharides

A

GLUT-2

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14
Q

what GLUT is the major transporter in the CNS

A

GLUT 3

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15
Q

tissue distribution of SGLT-1

A

intestinal epithelial cells

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16
Q

tissue distribution of SGLT-2

A

kidney (tubular epithelial cells)

17
Q

which transporters are Na+ dependent

A

SGLT 1 and 2

18
Q

which transporters operate through facilitated diffusion

A

the GLUTs