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UE2 > Transport membranare > Flashcards

Transport membranare Flashcards

1
Q

T1/2 eau

A

100ms

diffusion simple

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2
Q

Porine présence

A

membrane mito ext

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3
Q

Canaux

A

10^7 à 10^9

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4
Q

Transporteurs

A

100 à 10 000

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5
Q

ATPases

A

1 à 1000

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6
Q

Aquaporine nombre

A

300 connues
12 chez homme
3 isoforme au niv du rein

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7
Q

Aquaporine chaine polypeptidique

A

6 helice alpha transmembranaires

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8
Q

Aquaporine au milieu canal

A

2 boucles replié dans la bicouche lipidique
N = asparagine
P= proline
A= alanine

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9
Q

Transporteur ABC nombre

A

plus de 500 prot ≠

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10
Q

Transporteur ABC structure

A

1 chaine polypeptidique
2 motifs
- 6 helices Alpha transmb
- 1 cassette visant ATP

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11
Q

Transporteur ABC domaine de fixation

A

partie intracellulaire

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12
Q

ATPasa ionique : type F

A

transport proton

uniquement mb mito int

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13
Q

ATPasa ionique : type F inhibé

A

oligomycine

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14
Q

ATPasa ionique : type V

A

acidification des vacuoles intracellulaires

les plus volumineuses

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15
Q

ATPasa ionique : type V inhibé

A

bafilomycine

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16
Q

ATPasa ionique : type P

A

transort cations

phosphore nécessaire à son fonctionnement

17
Q

ATPasa ionique : type P inhibé

A

Vanadate

18
Q

ATPasa ionique : type P sous unité alpha

A 
1 dom transmb 
3 domaines intrac 
- N = s'insere ATP 
- P = phospho au niv d'un acide aspartique
- A = déphospho
19
Q

NA+/K+ sous unité alpha

A
  • 8 helices alpha tranmb

- 3 dom NPA

20
Q

NA+/K+ sous unité beta

A

1 chaine polypeptidique à 1 Dom transmb

Glycolysée en extrac

21
Q

NA+/K+ nb ions

A

Liberation 3 ions NA+

Entrée 2 ions K+

22
Q

ddp cel euca normal

A

-60mV

23
Q

ddp cel ouabaine

A

-50mV

24
Q

Concentration en Calcium = sang (extrac)

A

10^-3M

25
Q

Concentration en Calcium = intrac

A

10^-7M

26
Q

Concentration en Calcium = RE sarcoplasmique

A

10^-2

27
Q

Inhibiteur SERCA

A

Thapsigargine

28
Q

Antiport NA+/CA+

A

entrée passive 3NA

Sortie active 1 ÇA

29
Q

Symport NA/glucose

A

2 NA

1 glucose

UE2 (7 decks)

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