Transport across cell membranes Flashcards
What is the cell surface membrane made up from?
Phospholipids
Proteins
Cholesterol
Glycolipids
Glycoproteins
How does a phospholipid bilayer form?
Hydrophilic phosphate heads
point to the outside of the cell surface membrane
Attracted to water either side
Hydrophobic fatty acid tails
point Into the centre of the cell membrane
Repealed by water either side
What is the function of the phospholipid bilayer?
Allow lipid soluble substances to move through the cell membrane
Prevent water soluble substances moving through the cell membrane
Make the membrane flexible and self sealing
What is the function of a protein that DOESN’T extend across the bilayer?
Give mechanical support to the membrane
Act as cell receptors
For cell identification
For hormones
Help cells adhere together
What is the function of a protein that DOES extend across the bilayer?
Act as channels for water soluble substances
Allow active transport across the membrane
Describe the properties of cholesterol
Occur within the phospholipid bilayer
Very hydrophobic
What is the function of cholesterol in the bilayer?
Reduce movement of phospholipids /
Make the membrane less fluid at high temperatures
By pulling the fatty acid tails together
Prevent leakage of water and dissolved ions from the cell
What is a glycolipid?
A carbohydrate covalently bonded to a lipid
Extends from the bilayer
What is the function of glycolipids in the bilayer?
Recognition sites
Maintain membrane stability
Help cells to adhere
To form tissues
What is a glycoprotein?
Carbohydrate chains attached to extrinsic proteins
On the outer cell surface of the membrane
What is the function of glycoproteins in the cell membrane?
Cell recognition sites
Hormone and neurotransmitter receptors
Help cells adhere
To form tissues
What is the function of membranes WITHIN a cell?
Control movement into and out of discrete organelles
Separate organelles from the cytoplasm
So metabolic reactions occur in the organelle
Provide an internal transport system
Isolate enzymes that may damage the cell
Provide surfaces for reactions to occur
What molecules CANNOT diffuse across the cell surface membrane?
Non lipid soluble molecules
Large molecules
Charged ions (same as the protein channel)
Polar molecules
Define the term fluid mosaic
Fluid: individual phospholipid molecules are not bonded and can move relative to one another
Giving the membrane a flexible structure constantly changing shape
Mosaic: proteins embedded in the bilayer vary in shape size and pattern
Like that of mosaic tiles
Define diffusion
The net movement of particles or ions
From a region of high concentration
To a region of lower concentration
Until even distribution is reached
Down a concentration gradient