Transplantation

Question 1

what are the origins of human transplant donation

Answer 1

deceased after brain death

decreased after cardiac death

Question 2

what are some of the main potential complications of transplantation

Answer 2

post transplantation injection
post transplantation malignancy
transplant rejection

Question 3

what are the different types of graft rejection

Answer 3

hyper acute
acute
chronic

Question 4

how long does hyper acute graft rejection take

Answer 4

minutes-hours

occurs typically if graft not matched correctly or antibodies not removed

Question 5

how long does acute graft rejection take

Answer 5

months-years

Question 6

how long does chronic graft rejection take

Answer 6

10-20 years

Question 7

what is the mechanism of T-cell mediated graft rejection

Answer 7

APC meets T-cell in lymph node and activates it

Question 8

what is the mechanism of antibody-mediated graft rejection

Answer 8

antibody against graft HLA or AB) antigen binds to transplanted tissue and causes immune response