Transplantation

Question 1

Treatment Strategies for ESRD

Answer 1

no treatment
-hospice
hemodialysis
-bridge to transplantation
-permanent
peritoneal dialysis
renal transplantation

Question 2

Broader application of transplantation

Answer 2

alter donor kidney to make it acceptable
develop tests of donor-recipient compatibility
reduce the strength of the recipient immune system

Question 3

outcome of live donor renal transplants

Answer 3

outcomes have improved with use of the newer drugs is inescapable.
as short-term outcomes have improved, the attention of the transplant community has shifted to considering ways of reducing the long-term effects of chronic maintenance immunosuppression in an effort to increase long-term patient survival.

Question 4

patient survival rate until five years

Answer 4

the highest rate of survival for years after transplantation fall under those that had a kidney replacement

Question 5

waiting list

Answer 5

most people waiting or a transplant are waiting for a kidney

Question 6

what does the OPO do?

Answer 6

organ procurement organizations do:

• education of hospital staff about donation
• organ donor management
• organ recovery
• tissue donation and recovery
• donor family support
• data collection & reporting
• research
• public education

Question 7

what was the expanded criteria donor?

Answer 7

• age 60 or greater
• age 50-50 with at least 2:
• history of HTN
• CVA (cerebrovascular accident) as cause of death
• terminal creatinine > 1.5 mg/dl

Question 8

ECD - KDPI > 85%

Answer 8

• 1/3 fail within 3 years
• SCD - 20% fail at 3 years
• allocation to select group of patients
• 41% of ECD kidneys are discarded
• high-KDPI recipients have survival benefit over wait-listed patients

Question 9

what is important to look for in donors that could be harmful?

Answer 9

donor transmitted infection

Question 10

living donor relation to recipient for kidney

Answer 10

1) biological sibling
2) other unrelated
3) offspring
4) parent
5) spouse unrelated