Transplant Flashcards

1
Q

Levels of Osteopenia

A

-1 to -2.5

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2
Q

Levels of Osteoporosis

A

-2.5 or higher

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3
Q

Calcium Channel Blockers

A

Affect tacro and cyclo

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4
Q

Warrants Dexa Scan

A

chronic steroid use and chronic use diuretics

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5
Q

Meds typically associated with gingival hyperplasia

A

cyclosporine, anticonvulsants, ca channel blockers

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6
Q

Cyclosporine

A

Hypertension

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7
Q

Antiproliferative Agent

A

Mycophenolate mofetil

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8
Q

Anti-thymocyte globulin shown to reduce

A

Delayed graft function

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9
Q

Medications not removed by dialysis

A

tacro, mycophenolate, antithymocyte globulin, cyclosporine

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10
Q

Herbs

A

SUBtheraputic drug levels (i.e. St. John’s Wort)

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11
Q

Least impact on WBC

A

Cyclosporine

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12
Q

AMR

A

vascular inflammation and damge. Endothelial activation and intravascular macrophages and capillary destruction. Treat with IVIG (Rituximab)

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13
Q

Release in the stomach

A

Mycophenolate

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14
Q

Released in small intestine

A

Myfortic

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15
Q

Can cause protein in urine

A

Sirolimus

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16
Q

“Mycins”

A

Increase tacrolimus levels

17
Q

Tacrolimus

A

Lower Mag, increase K and increase lipids

18
Q

Renal Artery Stenosis

A

Uncontrolled hypertension, impaired renal function, bruit over anastomosis. Need angioplasty to dilate or surgical repair.

19
Q

Liver Rejection

A

increased LFTs, pain, jaundice, dark urine, ascites, fever

20
Q

Kidney Rejection

A

Increased BUN/Cr, decreased urine output, weight gain, pain, edema, fever

21
Q

Heart Rejection

A

Arrhythmia, tachy or brady, hypotension, SOB, weight gain, fatigue, fever

22
Q

Lung Rejection

A

SOB, fatigue, prod. cough, fever

23
Q

Pancreas Rejection

A

Hyperglycemia

24
Q

Intestinal Rejection

A

change in stool output, fatigue, pain or distention, dusky stoma, weight loss, fever

25
Q

Severity of cellular rejection

A

Based on Degree of tubilitis and arteritis

26
Q

Renal Vein Stenosis

A

Kidney cannot be salvaged; expect return to dialysis and list for retransplant

27
Q

Priority when offering deceased kidney donor

A

highly sensitized, patients who are 0mm with donor, pediatric patients

28
Q

Lung Cold ischemia times

A

6 hours

29
Q

Heart Cold Ischemia

A

4 hours

30
Q

Liver Cold Ischemia

A

12 hours

31
Q

Small Intestine Ischemia

A

6 hours

32
Q

Kidney Cold ischemia

A

24 hours