Transplacental infections (Torches) Flashcards
Which medications are used for toxoplasmosis?
Sulfadiazine or pyrimethamine
Atovaquone or clindamycin
Is the rubella virus enveloped?
Yes
Where does the rubella virus replicate?
Cytoplasm
Is the rubella virus nonsegmented?
Yes
Is the rubella virus double or single stranded?
Single
What other conditions can result from a rubella infection?
Mental retardation, microcephaly, intrauterine growth retardation, thrombocytopenic purpura, hepatosplenomegaly, progressive post-rubella panencephalopathy
Is treponema pallidum poorly gram staining?
Yes
Treponema pallidum is a
Extracellular spirochete
Is treponema pallidum gram positive or negative?
Negative
Treponema pallidum have
Corckscrew motility
Is treponema pallidun difficult to culture?
Yes
Is treponema pallidum visible under dark field microscopy?
Yes
What are some symptoms of congenital syphilis?
Rhinitis, rash of secondary stage, bone deformations
How do we diagnose treponema pallidum?
IgM tests
How do we treat treponema pallidum?
Penicillin G
Where does the parvovirus B19 replicate?
Nucleus
Parvovirus can lead to
Abortion/miscarriage
Hydrops fetalis
Anemia
How is parvovirus diagnosed?
Serology and PCR
Which bacteria can be transferred from the maternal normal flora due to a difficult labor?
Strep agalactiae
Strep agalactiae can cause what?
Bulging fontanelles (hydrocephalus) , irratibility
Where is strep agalactiae detected?
CSF
What shape is listeria monocytogenes?
Gram positive rods
Listeria monocytogenes is the third cause of
Neonatal meningitis
How is listeria monocytogenes transmitted?
Maternal normal flora