Transplacental infections (Torches) Flashcards

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1
Q

Which medications are used for toxoplasmosis?

A

Sulfadiazine or pyrimethamine

Atovaquone or clindamycin

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2
Q

Is the rubella virus enveloped?

A

Yes

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3
Q

Where does the rubella virus replicate?

A

Cytoplasm

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4
Q

Is the rubella virus nonsegmented?

A

Yes

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5
Q

Is the rubella virus double or single stranded?

A

Single

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6
Q

What other conditions can result from a rubella infection?

A

Mental retardation, microcephaly, intrauterine growth retardation, thrombocytopenic purpura, hepatosplenomegaly, progressive post-rubella panencephalopathy

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7
Q

Is treponema pallidum poorly gram staining?

A

Yes

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8
Q

Treponema pallidum is a

A

Extracellular spirochete

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9
Q

Is treponema pallidum gram positive or negative?

A

Negative

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10
Q

Treponema pallidum have

A

Corckscrew motility

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11
Q

Is treponema pallidun difficult to culture?

A

Yes

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12
Q

Is treponema pallidum visible under dark field microscopy?

A

Yes

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13
Q

What are some symptoms of congenital syphilis?

A

Rhinitis, rash of secondary stage, bone deformations

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14
Q

How do we diagnose treponema pallidum?

A

IgM tests

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15
Q

How do we treat treponema pallidum?

A

Penicillin G

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16
Q

Where does the parvovirus B19 replicate?

A

Nucleus

17
Q

Parvovirus can lead to

A

Abortion/miscarriage
Hydrops fetalis
Anemia

18
Q

How is parvovirus diagnosed?

A

Serology and PCR

19
Q

Which bacteria can be transferred from the maternal normal flora due to a difficult labor?

A

Strep agalactiae

20
Q

Strep agalactiae can cause what?

A

Bulging fontanelles (hydrocephalus) , irratibility

21
Q

Where is strep agalactiae detected?

A

CSF

22
Q

What shape is listeria monocytogenes?

A

Gram positive rods

23
Q

Listeria monocytogenes is the third cause of

A

Neonatal meningitis

24
Q

How is listeria monocytogenes transmitted?

A

Maternal normal flora

25
Q

Listeria monocytogenes can cause

A

Hydrocephalus

26
Q

Where is listeria monocytogenes detected?

A

CSF

27
Q

How is listeria monocytogenes treated?

A

Ampicillin with or without aminoglycoside