Transfusion Reactions Flashcards
A transfusion reaction is a reaction to blood transfusion or its components. It can be acute or delayed. Differentiate based on time
Acute - During first 24 hours
Delayed - >48 hours until days and weeks after
Transfusion reactions can be immune-mediated or non-immune mediated. Give me 3 ddx for each of the following:
Acute Immune mediated:
Delayed Immune mediated:
Non-immune mediated:
What is the most common transfusion reaction?
What is the most severe transfusion reaction?
Give the pathophysiology, signs and symptoms, as well as management of the following transfusion reaction:
Febrile transfusion reaction
Give the pathophysiology, signs and symptoms, as well as management of the following transfusion reaction:
Haemolytic transfusion reaction
What is the main risk factor for allergic transfusion reactions?
IgA deficiency
Give the pathophysiology, signs and symptoms, as well as management of the following transfusion reaction:
Allergic reaction +/- anaphylaxis
Give the pathophysiology, signs and symptoms, as well as management of the following transfusion reaction:
TRALI
What are the main RF for TACO?
HF or Renal disease
Transfusion-associated Circulatory overload
Give the pathophysiology, signs and symptoms, as well as management of the following transfusion reaction:
TACO
