Transcription Factors

Question 1

Proto-oncogene product that can associate with fos protein, product of another proto-oncogene

Activity induced by C-kinase activation

Answer 1

Jun (AP1)

Question 2

Induced by C-kinase activation

Answer 2

AP2

Question 3

Induced by A-kinase activation

Answer 3

ATF (CREB)

Question 4

Binds to promoters of many housekeeping genes

Answer 4

SP1

Question 5

Ubiquitous in mammalian cells. One of several proteins that bind to same octamer sequence

Answer 5

OTF1

Question 6

Several proteins encoded by alternatively spliced RNAs from one gene

Answer 6

NF1 (CTF)

Question 7

Mediates transient transcriptional activation of fos proto-oncogene by growth factors. Binds as dimer to symmetric DNA sequence

Answer 7

SRF