TRALI Flashcards

1
Q

TRALI

A

hypoxia, hypotension
mechanical ventilation in MAJORITY of pts
rapidly resolves in 3 days
Mortality is much lower than other ALI

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2
Q

TRALI mechanism

A

Leukocyte ab in donor blood react to antigens on recipient’s granulocytes

some cytokines and lipids in donor blood could cause inflammation

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