Tracheal Tumors Flashcards
Most tracheal tumors are benign or malignant?
Malignant
(MC SCC and adenoid cyststic carcinoma)
MC primary malignant tracheal tumors
- SCC
- Adenoid cystic carcinoma
- Less common tumors:
- Carcioids
- Bronchogenic carcinoma
- Sarcoma
Demographics of SCC and adenoid cystic carcinoma of trachea
- MC in men (both)
- MC in smokers (both)
- Adenoid cystic: earlier in life (40-50 years old)
- SCC: older in life (60-70 years old)
SCC or Adenoid Cystic Carcinoma:
Invades LN and mediastinum
SCC
(Adenoid cystic metastasizes vis submucosa; less likely to spread to LN)
SCC or Adenoid Cystic Carcinoma:
Mestastasize vai submucoa
Adenoid cystic carcinoma
(SCC via LN)
MC tumors to metastasize to trachea
- Laryngeal ca
- Lung ca
- Thyroid ca
- Esophageal ca
MC presenting s/s of tracheal tumors
Slowly progressive obstructive respiratory sx (wheezing or stridor)
(often misdiagnosed as adult-onset asthma)
Diagnostic modalities utilized for tracheal tumors
- CT
- Bronchoscopy
- Rigid bronchoscopy (ID tumor location and external compression, biopsy)
Important principle for biopsies of tracheal tumor
Biopsy proximal and distal to visualized tumor
(accurately map tumor tumor size and involvement)
During dissection of the trachea, how much of the trachea can be delivered into the neck with hyperextension
50% of the length
Location of the blood supply to the trachea
Lateral borders
(fusion of inferior thyroid, bronchial, and internal thoracic arteries)
Location of Right and Left recurrent laryngeal nerve in relation to trachea
- Right: along upper to mid trachea
- Left: along majority of the entire length of trachea
Indicatins for tracheal resection and reconstruction for tracheal tumors
- Lack of metastatic disease
- Ability to determine resectibility
Resectibility of tracheal tumors depends upon which factors:
- Length of trachea required for resection
- Extent of invasion into adjacent strucutres
- Patients functional status
Maximum amount of trachea that is usually amenable to reconstruction
Up to 6 cm
Hallmark feature of a durable repair after tracheal resection
Tension-free anastomosis
Options for surgical exposure of the trachea
- Cervical collar incision (upper trachea, adequate for most resections)
- T-extension (inclues upper sternotomy)
- Right thoracotomy (lower trachea, carina)
Excessive lateral longitudinal dissection of trachea should be avoided to prevent what
Tracheal devascularization
Inadvertant injury to RLNs
5 Classic Release Maneuvers for tracheal resection (in preferred order)
- Pretracheal dissection
- Neck flexion to 30 degrees with chin to sternum stitch
- Laryngeal release (“drop” the larynx, cricoid, trachea)
- Inferior pulmonary ligament release
- Hilar release (incision of right pericardium, mobilization of RPA and SPV)
More advanced release maneuver utilized if 5 classic techniques fail
Transection of left main bronchus with re-implantation onto right main bronchus
Most serious complication after tracheal resection and reconstruction
Anastomotic dehiscence
Presentation of anastomotic dehiscence after tracheal resection and reconstruction
Days to Weeks after surgery
- Wound infection
- SQ air
- Voice change
- Stridor
- Airway obstruction
TOC for tracheal anastomotic dehiscence
- Tracheostomy (maintain open airway)
- Drain infection
- Control defect (tracheostomy tube or soft tissue/muscle flap)
(Delayed reopeation to repair)
SCC or Adeonoid cystic carcinoma:
Better overall survival
Adenoid cystic carcinoma
Other than histology, most important prognostic factor for tracheal tumors
Completness of resection
Management approach for:
- positive distal margin after resection
- inability to completely resect tumor without undue tracheal tension
Adjuvant XRT
(better to leave anastomosis tension-free than to resect too much)
Palliation options for unresectable tracheal tumors
- Rigid bronchoscopy: dilation of strictures and coring out of tumors
- Laser ablation
- Tracheobronchial stents
Characteristic of tracheobronchial stents
- Efficacous in proximal airways (trachea or mainstem bronchi)
- Prone to migration
- Aggressive mucolytic required
Role of adjuvant XRT for resected tracheal tumors
- All resected SCC and adenoid cystsic tumors should receive adjuvant XRT (after anastomosis has healed)
Treatment options for unresectable tracheal tumors
XRT + palliative procedure
(palliative procedures: rigid bronch with dilation/core, laser ablation, stent)