Trace Metals Terms Flashcards
A metal that has a high atomic weight with a specific gravity that exceeds the specific gravity of water by five or more times at 4° C and may include Trace Metals of a Public Health Concern including Hg, Pb, As, Cd and Cr is the definition for?
Heavy Metals
What are trace metals?
metals that occur naturally in trace concentration within the crust of the Earth
What are Hyperactivity Syndrome and/or Overt Aggressiveness ?
brain effects of Pb trace metal exposure in humans and rats. In humans this leads to learning disorders.
What is methyl mercury?
most toxic form of Hg
What is Sulfhydryl Groups on Amino Acids
active sites on proteins in which Hg outcompetes the Sulfur for binding, leading to Hg preferentially binding with proteins that are inactivated as a result
What is Minamata Bay
a fishing village which was the location of major human Hg Poisoning in Japan
What is the annual economic impact of Hg in the US?
> $2<$44 Billion/Year
– gasoline which contained Pb as an octane booster additive which resulted in major Pb contamination along roadways in the US.
Leaded Gasoline
name given to Pb Paint Chips which taste sweet and may be consumed by toddlers/infants leading to childhood Pb poisoning
PICA
an enzyme that catalyzes the formation of hemoglobin (heme + globin protein) which is adversely affected by Pb exposure resulting in anemia
-Ferrochelatase
wrist drop which is a condition in industrial workers excessively exposed to Pb in which they lose muscle control over the wrist, resulting in the wrist drooping
Pb Palsy
damage to the kidney caused by trace metals such as Pb and Cd
-Nephritis
Antidote for Adult Pb Exposure
Ca-EDTA
- Antidote for Inorganic Hg
- Dimercaptopropanol
Antidote for Organic Hg
Pennicillamine