TRACE ELEMENTS Flashcards
Consist of metals, except selenium, the halogens, fluoride and iodine
TRACE ELEMENTS
Are important for maintenance of normal health, and tissue and organ functions.
TRACE ELEMENTS
Have specific in vivo metabolic functions that cannot be effectively performed by other similar elements
TRACE ELEMENTS
Concentration in tissue: ______ of wet tissue and _____ of dry body weight
< 1ug/g of wet tissue and
<0.01% of dry body weight
FUNCTION:
Enhances insulin action; for glucose and lipid metabolism
CHROMIUM
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Insulin resistance, impaired glucose
tolerance (type 2 DM), hyperipidemia
CHROMIUM
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Skin ulcers, renal and hepatic necrosis
CHROMIUM
FUNCTION:
Hemoglobin synthesis; component of B₁₂
COBALT
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Anemia, growth depression
COBALT
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Heart failure, hypothyroidism
COBALT
FUNCTION:
Cellular respiration; collagen synthesis
COPPER
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Menkes’ kinky hair syndrome muscle weakness
COPPER
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Interferes with absorption of iron and zinc
COPPER
FUNCTION:
Prevents dental carries
FLOURINE
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Dental carries
FLOURINE
FUNCTION:
Thyroid hormone synthesis
IODINE
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Goiter, cretinism, myxedema
IODINE
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Thyrotoxicosis
IODINE
FUNCTION:
Oxygen transport, component of
hemoglobin
IRON
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Anemia
IRON
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Hemachromatosis
IRON
FUNCTION:
Bone and connective tissue functions
MANGANESE
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Skeletal defects
MANGANESE
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Psychiatric disorders,
Parkinson’s disease
MANGANESE
FUNCTION:
DNA metabolism
MOLYBDENUM
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Growth depression, cretinism, goiter
MOLYBDENUM
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Anemia, thyrotoxicosis
MOLYBDENUM
FUNCTION:
Prevents oxidative damage of lipid
SELENIUM
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Keshan disease
SELENIUM
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Hair and nail loss, liver failure
SELENIUM
FUNCTION:
Protein synthesis
ZINC
DEFICIENCY OF THIS TRACE ELEMENT LEADS TO:
Acrodermatitis enteropathica, growth retardation, immune
deficiency, infertility, delayed wound healing, osteoporosis
ZINC
TOXICITY OF THIS TRACE ELEMENT LEADS TO:
Gastrointestinal irritation
ZINC