toxins and drugs affecting synaptic transmission Flashcards by Lydia Payton | Brainscape

Q

nicotine

A

AChR agonist

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Q

physostigmine

A

AChE inhibitor

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Q

D-tubocurarine (curare)

A

Competitive inhibitor of the AChR

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Q

tetrodotoxin

A

Blocks voltage-gated sodium channels

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Q

Saxitoxin

A

blocks voltage gated sodium channels

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Q

conotoxin

A

blocks voltage gated calcium channels

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Q

tetanus toxin

A

cleaves synaptobrevin

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Q

botulinum toxin

A

cleaves synaptobrevin/syntaxin, SNAP-25

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Q

succinylcholine

A

AChR agonist

inactivates end-plate sodium channels

desensitization of the AChR

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Q

Organophosphate compounds

A

irreversible inhibition of AChE

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