Toxins Flashcards
1
Q
Increased cAMP toxins
A
- E.coli ETEC: heat-labile (diarrhea)
- Anthrax (diarrhea)
- Vibrio Cholerae (diarrhea)
- B.pertussis (inhibits phagocytosis)
2
Q
Protein synthesis toxins
A
- Diptheria: EF-2 inhibition
- P.aeruginosa: EF-2 inhibition
- Shigella: inhibit 60s
- E.coli (EHEC): inhibits 60s
3
Q
Neurotransmitter toxin
A
- C.tetani
- C.botulinum
- prohibit neurotransmitter release by blocking vesicle fusion
4
Q
Membrane Lysing Toxins
A
- C.perfringens: degredation of phospholipids
- S.pyrogenes: lyses RBC’s
5
Q
Toxic Shock Toxins
A
- S.aureus
- S.pyogenes
- binds MHCII and TCR to cause super release of IL1, IL2, TNFa, INFy
