Toxicology POPCORN Flashcards

1
Q

Which med toxicity?

  • Seizures
  • Prolonged PR
  • Tx= Glucagon, Insulin-Glucose, Epi
A

Beta-Blockers

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2
Q

Which med toxicity?

  • Seizures
  • Ileus
  • AV dissociation
  • Prolonged PR
A

Calcium channel blockers

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3
Q

How do you tx calcium channel blocker toxicity?

A

CaCl, Glucagon, Insulin-Glucose, Lipid emulsion

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4
Q

Which toxicity?

  • Seizure
  • Pinpoint pupils
  • Sweating
A

Organophosphates (=pesticides)

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5
Q

What does arsenic and organophosphates smell like?

A

GArlic=

Arsenic and Organophosphates

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6
Q

What does sulfide smell like?

A

Rotton eggs

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7
Q

What does Isopropyl alcohol smell like?

A

Acetone

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8
Q

What does Chloral hydrate smell like?

A

Pears

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9
Q

Activated charcoal should only be used within how many hours?

A

Within the 1st hour

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10
Q

What is the most common EKG abnormality found in OD pt ?

A

Sinus Tachycardia

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11
Q

Which toxidrome and what is the antidote?

  • Hot
  • Blind
  • Dry
  • Red (flushed)
  • Mad agitated
  • Fixed dilated pupils
  • hyperthermic
  • DRY ARMPITS
A

Anticholinergics (ex: Antihistamines, TCAs)

Antidote= Physostigmine (ACHase inhibitor)

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12
Q

What syndrome?

  • Myoclonus
  • Agitation
  • Diarrhea
A

Serotonin syndrome (combo of 2 SSRIs, Demerol, Lithium)

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13
Q

The following is caused by which group of meds? What is the antidote?

  • Pinpoint pupils
  • Resp. Depression
  • Hypotension
  • Bradycardia
A

Opiates (Fentanyl, Heroin, Morphine, Codeine)

Antidote= Naloxone

(Hint: oPIates= PIn point pupils)

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14
Q

What is the MC drug OD?

A

Acetaminophen

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15
Q

Which med OD? What is the antidote?

  • Liver necorsis
  • Vomiting MCly seen in kids
  • Toxic dose= 140mg/kg
A

Acetaminophen

Antidote= N-acetylcysteine

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16
Q

Which group of meds can cause the following toxicities? What is the antidote?

  • Respiratory Alkalosis
  • Metabolic acidosis
  • Hypokalemia
A

Salicylates (ASA, methylsalycylate/oil of wintergreen)

Antidote= Urine alkalization

17
Q

What is the antidote for a salicylate overdose? (ex: aspirin, methysalicylate/oil of wintergree)

A

Urine alkalization

18
Q

What causes the following toxicities?

  • Metabolic acidosis
  • Hypoglycemia
  • Elevated anion gap
  • Normal osmolarity gap
  • Normal lactate
  • VERY elevated ketosis
A

Ethanol

19
Q

How do you treat an ethanol toxicity

A

Fluids- Banana bag w/ MVI, thiamine, folate

20
Q

What do you see in the urine of someone who has consumed ethylene glycol (antifreeze). What is the tx?

A

Oxalate Crystalluria (If you use a woods lamp it will fluress purple)

Tx: IVF, Fomepizole (antidote)

21
Q

Which toxic alcohol has an anion gap metabolic acidosis with visual changes?

A

Methanol

(antidote=Fomepizole)

22
Q

Which med causes the following toxicities and what is the antidote?

  • Yellow halos in vision
  • Hyperkalemia
  • Arrhythmia
A

Digitalis

Tx= Digibind

23
Q

What is the MCC of unintentional poisoning death and has the following sxs:

  • Red skin
  • Apnea
A

CO

24
Q

How do you tx CO poisoning?

A

100% O2

25
Q

What is the MCC of peds mortality from poisoning?

A

Iron

26
Q

Which med causes the following toxicities and is MC in kids? What is the antidote?

  • Metabolic acidosis
  • Vomiting
  • Organ failure
A

Iron

Antidote= Deferoxamine (DFO)

27
Q

The following is the toxidrome for which group of meds?

  • ↑BP and HR
  • Delusions
  • Hyperthermia
  • Seizure
  • _*Diaphoresis*_
  • Piloerection
  • Mydriasis
  • Hyperreflexia
A

Sympathomimetics (Amphetamines, cocaine, pseudophedrine, caffeine, PCP)

(note- This is the same as the anticholinergics but sympathomimetics have DIAPHORESIS)