Toxicology & Antidotes Flashcards

1
Q

Acetaminophen antidote

A

N-acetylcysteine (acetadote)

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2
Q

Tricyclics antidotes

A

Sodium bicarb

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3
Q

Opioid antidote

A

narcan

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4
Q

Benzos antidote

A

Romazicon (Flumazinil)

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5
Q

Ca Channel Blocker antidote

A

Calcium, glucagon, insulin

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6
Q

Beta blocker antidote

A

Glucagon, insulin

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7
Q

Organophosphates antidote

A

Atropine/2-PAM

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8
Q

Ethylene glycol antidote

A

Fomepizole (Antizol)

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9
Q

Iron antidote

A

Deferoxamine

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10
Q

ToxSulfonylureas

A

Dextrose, octreotide

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11
Q

S/s of Iron Overdose

A

n/v & abdominal pain then hematemesis

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12
Q

Tx for Iron Overdose

A

-No charcoal (heavy metals do not bind)
-Desferal is antidote and is a chelating agent, excreted renally

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13
Q

Side effects of Desferal (Deferoxamine)

A

Rust, pink, or rose colored urine

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14
Q

When does tylenol level peak in blood?

A

4 hours

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15
Q

What labs need to be monitored in tylenol overdose?

A

LFTs

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16
Q

Tx for tylenol overdose (3)

A

Lavage, activated charcoal, acetadote (within 8 hours for best results)

17
Q

S/s of salicilate overdose (5)

A

Tachypnea (compensate for metabolic acidosis)
N/v
Abdominal pain
Tinnitus
Hypoglycemia

18
Q

Treatment for salicylate overdose (3)

A

sodium bicarb for urine alkalinization
dexotrose for hypoglycemia
dialysis

19
Q

S/s of TCA overdose (3)

A

Coma, Cardiac dysrhythmia, convulsions

20
Q

Tx for TCA overdose

A

Intubation
Sodium bicarb
Lidocaine + mag if polymorphic vtach develops