Toxicology and Psychology Flashcards
Acetaminophen
Pain and fever
Non-narcotic analgesic, not anti-inflammatory
Toxic to liver - antidote is activated charcoal and n-acetylcysteine
Acyclovir
Herpes infections
Antiviral
Aspirin
Pain and fever
NSAID antidote is IV fluids and sodium bicarb
Overdose - Tinnitus and respiratory acidosis
Benadryl
Allergic reaction
Antihistamine - anticholinergic
Cocaine
Pain and recreation
Non-opioid narcotic - local anesthetic effect, dilated pupils
Codeine
Pain and recreation
Narcotic
Chlorpromazine
Schizophrenia
Anti-psychotic
Colchicine
Gout
Anti-inflammatory
Heroin
Pain and recreation Opioid narcotic (poisoning looks like pinpoint pupils, coma and respiratory depression) Antidote nalaxone
Ibuprofen
Pain and fever
NSAID
Iron sulfate
Anemia
Mineral supplement - OD vomiting, diarrhea, ab pain, liver failure
Antidote desferoxamine
Imipramine
Depression, fibromyalgia, CFS
Tricyclic antidepressant - anticholinergic
Haldol
Insomnia
Sedative hypnotic
Naprosyn
Pain
NSAID
Valium
Anxiety and insomnia
Benzodiazipine sedative
Response to exposure that is less than expected
Antagonistic
Cancer risk values are over how many years?
70
Lethal dose 0/50
Lowest dose of a substance (dose of) introduced by any route other than inhalation which has been reported to have caused death in humans or animals (cause death 50% of defined experimental animal population)
LOAEL
Lowest observed adverse effect level to cause harm effects in people or animals
MRL
Minimal risk level
Dose of substance below which it is unlikely to cause harm
NOAEL
Highest tested dose that has been reported to have NO adverse effects level on people/animals
Any substance that injures or kills living things
Toxicant
VOC
Volatile organic compound - readily evaporate into air
Benzene, toluene, methylene chloride
If pt has HTN, elevated temperature, dilated pupils, rapid pulse what is the overdose on?
Antidepressants
Aflatotoxin
Poisoning
Poison produced by fungi (Aspergillus flavus)
Liver damage –> hepatocellular carcinoma
Arsenic
Poisoning
Chemical interferes w/pyruvate dehydrogenase, smells like garlic antidote is chelating agent like dimercaprol
Headaches, confusion, diarrhea, hematuria, drowsiness
Barbituate
Sedative hypnotic drug; respiratory depression, dilated pupils
Beta blockers
Tx HTN
Cause hypotension and bradycardia