Toxicology Flashcards

1
Q

What is the Anticholinergic toxidrome

A
Hyperthermia 
Blindness, fixed pupils 
DMM/axilla, urine retention 
Delusions/hallucinations
Rash (red) 
abd distention
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2
Q

What are anticholinergics

A
Jimson weed
antihistamines 
antidepressants 
Carbamazepine 
TCA
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3
Q

What is the treatment for Anticholinergic toxidrome

A
ABC
supportive 
rapid cooling 
Benzos (Tx agitation) 
Paralytics (Vercuronium, Rocuronium) 
Physostigmine (caution, causes cholinergic syndrome)
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4
Q

What is the Cholinergic toxidrome

A

SLUDGE
salivation, lacrimation, urination, defecation, GI cramp, emesis
sweating, miosis, blurred vision

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5
Q

What are Cholicergics

A

Insecticides

Organic pesticides

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6
Q

What is the treatment for Cholinergic toxidrome

A

Atropine q3-5 min

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7
Q

What is the Sympathomimetic toxidrome

A

Hyperthermia
Diaphoresis
Mydriasis
HTN, tachy, delusions, sz, hyperreflexia

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8
Q

What causes Sympathomimetic toxidrome

A
APAP
cocaine
Ephedra
Caffeine
PCP
Coke
Bath salts
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9
Q

How do you treat Sympathomimetic toxidrome

A

FLUIDS BABY

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10
Q

What are symptoms of Serotonin Syndrome

A
Confusion--Agitation--Seizure--Coma
Fever
Tachycardia
Diarrhea
Mydriasis 
Ataxia
Hyperreflexia
Clonus
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11
Q

What can cause Serotonin Syndrome

A
SSRI
Meperidine
Amitryptaline
MAO-I 
Fluoxetine
MDMA
Selegeline 
Tramadol
Venlafaxine 
Lithium
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12
Q

How do you treat Serotonin Syndrome

A

Remove offending agent
Reduce temp
Caustion with benzo use

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13
Q

What are symptoms of Opiate toxidrome

A

Pinpoint pupils
Depressed respirations
AMS
hypoxia

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14
Q

What are opiates

A

Fentanyl
Codeine
Meperidine (demerol)

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15
Q

How do you treat opiate toxidrome

A

NARCAN (naloxone)

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16
Q

What does NOT show up on a UDS

A
meperidine
hydrocodone
oxycodone
methadone
lomotil
tramadol
fentanyl
17
Q

What causes an anion gap

A
CUTER DIMPLES 
Cyanide 
Uremia 
Toluene 
Ethanol 
Rhabdo,RTA 
DKA
Isoniazid, iron
Methanol 
Propylene glycol 
Lactate 
Ethylene glycol 
Salicylates
18
Q

What decreases an anion gap

A

Lithium
Bromide
Low albumin
multiple myeloma

19
Q

What are ways to clear the stomach after an OD

A
Gastric lavage (w/in 60 min of ingest)- put in LLD position
Activated charcoal 
Whole bowel irrigation (Golyteyl) 
Ipecac syrup 
IV lipid emulsion
20
Q

What is the # for poison control

A

1-800-222-1222

21
Q

What is calculation for osmolar gap

A

Measured osmolality - Calculated osmolality = 10 or less (norm)

22
Q

What is calculated osmolar gap

A

2Ns + glucose/18 + BUN/2.8