Toxicology Flashcards

1
Q

Contents of Jar 1

A

Stomach content
30cm of proximal small intestine

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2
Q

Contents of Jar 2

A

500g midpart liver and GB
Half of both kidneys
±spleen

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3
Q

When is spleen persevered?

A

Cyanide poisoning

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4
Q

Contents of bottle 1

A

10mL femoral vein blood

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5
Q

Contents of bottle 2

A

10mL Urine

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6
Q

Best preservative for visceral organs

A

Rectified spirits (95% ethyl alcohol)

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7
Q

Rectified spirit is used to stop V organs in corrosive poisoning EXCEPT

A

Phenol, phosphorus, or alcohol

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8
Q

MC used preservative

A

Saturated salt solution

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9
Q

Preservative for blood

A

NaF and K oxalate

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10
Q

Preservative for urine

A

Thymol

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11
Q

Preservative for virology

A

Liquid N»glycerol

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12
Q

______ is opened first in poisoning case

A

Head

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13
Q

Chlorat hydrate> Paraldehyde
Odor

A

Acrid pear like odor

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14
Q

Cyanide odor

A

Bitter almond

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15
Q

Burnt rope odor

A

Cannibis

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16
Q

Odor for Arsenic Phosphorus, OPC

A

Garlicky

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17
Q

Odor for Celphos

A

Garlic and rotten egg

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18
Q

Odor for H2S and Zn/Al phosphides

A

Rotten egg

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19
Q

Odor for Nitrobenzene

A

Shoe polish

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20
Q

Gastric lavage contraindicated in

A

All corosives except carbonic acid

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21
Q

Adsorbents contraindicated in

A

Corrosives
Lithium
Iron
Metallic Methanol
Ethankl Ethylene glycol

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22
Q

Fever and tinittus

A

Asprin overdose

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23
Q

Hemodialysis Contraindicated in

A

Copper
Kerosene
Benzodiazapene
OPC
Digoxin

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24
Q

Indication for exchange transfusion

A

Thiophyllene poison
Severe Methhemoglobin

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25
Q

Antitode of severe meth hemoglobin

A

Methylene blue

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26
Q

PEG solution used in

A

While Bowel irrigation

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27
Q

Indication for whole bowel irrigation

A

Iron tablets
Lithium tablets
Body packers syndrome

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28
Q

Ophitoxemia

A

Poison by snake

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29
Q

COD in neurotoxic snake bites

A

Respiratory paralysis

30
Q

neurotoxic snakes?

A

Kraits
Cobra

31
Q

Bespectacled mark

A

Common cobra

32
Q

Furrowing of forehead
Ptosis
Opthalmoplegia

A

Neurotoxic snake bites

33
Q

Occult bite with abdominal pain

A

Krait bite

34
Q

Common krait bites inhibit

A

Ach release

35
Q

Cobra bite inhibits

A

M receptors

36
Q

Ach-estrase is inhibited by

A

Atropine and neostigmine

37
Q

COD in Vasculotoxic snakes

A

Hemorrhagic shock

38
Q

Vasculotoxic snakes

A

Vipers

39
Q

Types of vipers

A

Pitvipers
Pitless vipers

40
Q

Types of pitless vipers

A

Russell’s
Saw scaled

41
Q

Symptoms of Vasculotoxic snake bites

A

Pain
Uncontrolled bleeding
Lymphadenopathy
Blisters

42
Q

Monitoring for Vasculotoxic snake bite

A

20 minute whole blood clotting

43
Q

COD in musculotoxic snake bites

A

Renal failure by myoglobin

44
Q

musculotoxic snake?

A

Sea snake

45
Q

Symptoms of musculotoxic snakes?

A

Cramps
Myoglobinuria
Compartment syndrome
Hyperkalemia

46
Q

Compartment syndrome seen in

A

Sea snake bite

47
Q

Monitoring for musculotoxic snake bites

A

Increased CPK

48
Q

Pressure bandaging in snake bite

A

Sutherland wraps at 55mmHg

49
Q

Indication for PASV

A

Systemic toxicity
OR
Increasing local toxicity

50
Q

Initial dose of PASV

A

Powder form+10ml NS
8-10 vials

51
Q

Increase in BP then decrease in BP
Pulmonary edema
Pain
Bleeding

A

Scorpion bite

52
Q

Tx for scorpion venom with ↑BP and priapism

A

Antivenom and prazosin

53
Q

Tx for scorpion venom with ↓BP and priapism

A

Antivenom and dopamine infusion

54
Q

Priapism seen in

A

Scorpion bite
Blister fly bite
Trazodone

55
Q

Parathion
Paradon
Diazion
Chloropyrofios

A

Allyl Organophospahate compounds

56
Q

MoA of OPC

A

Inhibits Muscarinic and Nicontine receptors

57
Q

Antitode of OPC

A

Atropine

58
Q

OPC effect on Muscuranic receptor

A

Bradycardia

59
Q

OPC effect on Nicotinic receptor

A

Bradycardia

60
Q

Atropine toxicity causes

A

Fever

61
Q

Antitode before OPC aging

A

Oximes

62
Q

Oxime overdose symptoms

A

Increased OPC toxicity features

63
Q

Antidote if Organochlorine

A

Cholestyramine

64
Q

Damage to Type II Alveolar cells is called

A

Pneumotropism

65
Q

Do not give oxygen in herbicide poisoning because

A

It increases free radicles inside body

66
Q

Fatal dose of Celphos

A

1 tablet

67
Q

1 tablet of cephlos with saliva produces?

A

1gm phosphene gas
(Garlic fishy smell)

68
Q

Profound, refractory hypotension seen ib

A

Celphos poisoning

69
Q

COD in cephlos

A

Hypomagnesia

70
Q

Gold standard for dx of gas or alcohol poisoning

A

Gas chromatography