toxicologia Flashcards

1
Q

O que é substância tóxica?

A

São subs. capazes de causar dano ou morte
(todas as substâncias são tóxicas)

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2
Q

O que é agente tóxico?

A

Substância química de uma estrutura química definida

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3
Q

O que é toxina?

A

Substância de origem biológica

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4
Q

O que é toxicidade e quais suas classificações?

A

É a capacidade da substância química de produzir lesões. É classificada em aguda, sub-guda e crônica

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5
Q

O que é dose letal (DL)?

A

É a menor dose que causa morte

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6
Q

Defina DL1, DL50 e DL100

A

DL1: necessária para matar 1%
DL50: necessária para matar 50%
DL100: necessária para matar 100%

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7
Q

Qual a diferença entre peçonha e veneno?

A

Veneno é a substância tóxica expelida do animal e peçonha é a substância tóxica injetada pelo animal

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8
Q

What are the main phases of intoxication?

A

The main phases of intoxication are absorption, distribution, metabolism, and excretion.

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9
Q

True or False: The absorption phase is when the substance enters the bloodstream.

A

True

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10
Q

Fill in the blank: The __________ phase involves the body distributing the toxic substance to various tissues.

A

distribution

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11
Q

What is the primary organ responsible for the metabolism phase of intoxication?

A

The liver.

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12
Q

Multiple Choice: Which phase follows the metabolism phase in intoxication? A) Absorption B) Distribution C) Excretion D) None of the above

A

C) Excretion

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13
Q

What happens during the excretion phase of intoxication?

A

The body eliminates the toxic substance through urine, bile, or leite.

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14
Q

True or False: The distribution phase can impact the severity of intoxication.

A

True

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15
Q

What can affect the rate of absorption during the intoxication process?

A

Factors such as the route of administration, the chemical properties of the substance, and the individual’s metabolic rate.

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16
Q

Fill in the blank: The __________ phase is critical for reducing the toxicity of a substance.

A

metabolism

17
Q

What role does the kidney play in the excretion phase of intoxication?

A

The kidneys filter the blood to remove waste products and toxins, excreting them in urine.

18
Q

diferença entre tóxico e medicamento

19
Q

defina cinergismo

A

subs. que intencifica a ação da outra