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Infecto Repaso > Toxicologia > Flashcards

Toxicologia Flashcards

1
Q

Dosis tóxica paracetamol

A

200mg dosis única o 10g/kg peso
Dosis repetida >4g /24 horas

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2
Q

Sustancia que inactiva al paracetamol En Dosis terapéuticas

A

Glutation

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3
Q

Fase en la que se puede presentar insuficiencia hepatica encefaloatía y falla orgánica múltiple

A

Fase 3

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4
Q

Mejor estudio de laboratorio que indica falla hepatica o insuficiencia fulminante

A

INR>1
24h >2
48h>4
72h >6

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5
Q

Tiempo ideal para administrar N acetilcisteína

A

Primeras 8 horas

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6
Q

Dosis VO de N acetilcisteína

A

Inicial: 140mg/kg
Mantenimiento: 70mg/4h 17 veces

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7
Q

Dosis Ana acetilcisteína IV

A

150mg/kg 15-60 min
50mg/kg 4horas
100mg/kg 16 horas

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8
Q

Niveles sericos de paracetamol a las 4 horas indican:
Intoxicación
Posible
Probable
Alto riesgo

A

150 mcg
200mcg
300mcg

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9
Q

Efecto de la N acetilcisteína

A

Reduce absorción del paracetamol 25-60%

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Infecto Repaso (2 decks)

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