Toxicity and Deficiency

Question 1

nausea, vomiting, vision difficulties, skin dryness, hepatic injury, growth retardation

Answer 1

Vitamin A toxicity

Question 2

Thiamine deficiency

Answer 2

BeriBeri

Wernicke-Korsakoff syndrome

Question 3

Niacin deficiency

Answer 3

Pellagra: dementia, dermatitis, diarrhea

Question 4

Vitamin B12 deficiency

Answer 4

pernicious anemia, atrophic glossitis, shuffling gait

Question 5

hemorrhagic stroke, necrotizing enterocolitis in infants

Answer 5

Vitamin E excess

Question 6

false negative stool guaiac results

Answer 6

Vitamin C excess

Question 7

Causes of Vitamin A deficiency

Answer 7

insufficient diet (mental illness, alcoholism)
pancreatic insufficiency, cholestatic liver disease, biliary obstruction, intestinal malabsorption

Question 8

Vitamin deficiencies in primary biliary cholangitis

Answer 8

Fats, fat soluble vitamins

Question 9

cheilosis, Stomatitis, Glossitis

Answer 9

B2 riboflavin deficiency or B6 pyridoxine deficiency

Question 10

Megaloblastic anemia

Answer 10

B9 folate/folic acid or B12 cobalamin deficiency

Question 11

Neural tube defects

Answer 11

B9 folate/folic acid deficiency

Question 12

Dermatitis, dementia, diarrhea

Answer 12

B3 niacin deficiency

Question 13

Peripheral neuropathy

Answer 13

B1 thiamine or B3 niacin deficiency

Question 14

Neurologic deficits with upper and lower motor neuron involvement, sensory neuropathy

Answer 14

B12 cobalamin deficiency

Question 15

Petechial hemorrhages, gingival swelling, impaired wound healing, weak immune response

Answer 15

Ascorbic acid Vitamin C deficiency

Question 16

Symmetrical peripheral neuropathy with high-output CHF

Answer 16

B1 Thiamine deficiency (Wet BeriBeri)

Question 17

Wernicke-Korsakoff syndrome

Answer 17

B1 thiamine deficiency

Question 18

Lab tests for Vitamin B12 deficiency

Answer 18

elevated serum methylmalonic acid level

elevated serum homocysteine level

Question 19

Iron deficiency

Answer 19

anemia

Plummer-Vinson syndrome:

• dysphagia/esophageal web
• weakness, fatigue, dyspnea
• koilonychia (spoon nails)
• shiny red tongue