Toxicities and Tx Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

AchE inhibitors/organophosphates

A

atropine>pralidoxime

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3
Q

Antimuscarinic, anticholinergic agents

A

Physostigmine (crosses BBB), control hyperthermia

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4
Q

Arsenic

A

Dimercaprol, succimer

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5
Q

Benzos

A

flumazenil

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6
Q

B blockers

A

atropine, glucagon, saline

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7
Q

carbon monoxide

A

100% O2, hyperbaric O2

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8
Q

copper

A

penicillamine (copper pennies), trientine

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9
Q

cyanide

A

hydroxocobalamin, nitrites + sodium thiosulfate

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10
Q

Digitalis (Digoxin)

A

Digoxin-specific antibody fragments

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11
Q

Heparin

A

protamine sulfate

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12
Q

Iron (Fe)

A

Deferoxamine, deferasirox, deferiprone

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13
Q

lead

A

Calcium disodium EDTA, dimercaprol, succimer, penicillamine

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14
Q

mercury

A

Dimercaprol, succimer

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15
Q

methanol, ethylene glycol (antifreeze)

A

fomepizole > ethanol, dialysis

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16
Q

methemoglobin

A

methylene blue, vit. C (reducing agent)

17
Q

Opiods

A

Naloxone

18
Q

salicylates

A

NaHCO3 (alk urine), dialysis

19
Q

TCAs

A

NaHCO3 (stabilizes cardiac cell membrane)

20
Q

Warfarin

A

Vitamin K (delayed effect), PCC (prothrombin complex concentrate)/FFP (immediate effect)