Toxic Metals Flashcards
1
Q
Toxic metals of greatest concern
A
Be, Cd, Cr, Pb, Hg, Te, As (Metalloid but has similar effects to metals)
2
Q
Heavy Metal
A
Ill defined term that means a metal of high relative density (>5.0 g/cm3) eg. Pb: 11.4 g/cm3 Hg: 13.5 Cd: 8.7 As: 5.8 (metalloid)
3
Q
Why are most heavy metals an issue?
A
- derive toxicity from strong affinity to sulphur
- React w/ sulphydryl (-SH) groups which are present in the acitve sites of many enzymes eg amino acid: Cycteine
- Hg2+ Bonds to 2 enzymes SH (active sites), rendering both enzymes inactive
4
Q
Mercury
A
Answer to follow