Tox midterm 2 cont.

Question 1

DEREK

Answer 1

Toxicity prediction tool and expert knowledge base system
Deductive estimation of risk from existing knowledge
Learning set based on all genotoxicity data available
Rules based
Refers back to literature
Strong discussion of structure activity relationship (SAR) for alerts and mechanisms where understood

Question 2

VITIC

Answer 2

Defines and indicates composition of chemicals
Virtual international Toxicology Information center
Can be used to confirm a prediction by DEREK

Question 3

Sarah

Answer 3

Statistical based system 
QSAR 
Only genotoxicity 
Training set 9882 individual structures from the public and member donations
Molecules fragments
Amess test