Tox Flashcards

1
Q

Are comprehensive drug screens helpful?

A

not helpful, take too long

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2
Q

Coma Cocktail

A

50 cc of 50% glucose IV (amp of D50), Naloxone (lasts about 45 mins), Thiamine 100mg IV

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3
Q

Antidote for benzos

A

flumazenil

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4
Q

antidote for cyanide

A

lilly kit

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5
Q

Antidote for anticholinergics

A

physostigmine

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6
Q

antidote for beta blockers

A

glucagon

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7
Q

antidote for TCAs

A

Na Bicarb

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8
Q

Anion gap equation, and normal range

A

Na- (Cl + HCO3); normal is 5-15

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9
Q

Charcoal does not work with?

A
Iron
Lithium 
Cyanide
Pesticides 
Acids and Alkalis
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10
Q

What are the radiopaque pills you can see on KUB?

A
Chloral hydrate 
Heavy metals 
Iron 
Phenothiazines; packets of drugs 
Enteric coated pills 
Salicylates
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11
Q

What other substances have the anticholinergic toxidrome?

A

antihistamines, antipsychotics, TCAs, Carbamazepine, Cyclobenzaprine
Plants: Jimson weed and Belladonna

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12
Q

Major difference between antichol toxidrome and sympathomim toxidrome?

A

antichol: flushed dry skin, absent bowel sounds and distended bladder
sympathomim: normal skin or sweating, normal bowel sounds, bladder not distended

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13
Q

What toxins have cholinergic effects

A

pesticides, chemical warfare agents

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14
Q

sympathomimetic tx

A

benzo’s, cooling, iv fluids, charcoal

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15
Q

Opiates classic triad

A

respiratory decreased
depressed LOC
Miosis

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16
Q

What med can be used to tx serotonin syndrome

A

benzos

17
Q

Acetaminophen toxic values in adults and kids

A

7.5g in adults

150 mg/kg in kids

18
Q

Acetaminophen sx

A

typically few sx in 24 hrs, then malaise, nausea, RUQ pain

19
Q

Aspirin Sx’s

A

early/mild: tachycardia, tinnitus, n/v, abd ain, tachypnea, diaphoresis

late/severe: coma, seizures, resp depression, no-cardiogenic pulmonary edema, dehydration, shock.

20
Q

TCA EKG changes

A

first: sinus tach
terminal R wave in aVR
widened QRS
ventricular tachycardia

21
Q

How do you know if deferoxamine is working

A

“vin rose” urine

22
Q

Digoxin symptoms

A

n/v/d, bradyarrythmias, hyperkalemia, CNS sx’s, EKG with specific findings

23
Q

PE signs of alcohol withdrawal

A

tongue wag, tremor, tachycardia, low grade temperature

24
Q

Early GI symptoms within 2 hours from eating mushrooms is reassuring, true or false

A

true , delayed symptoms over 6 hrs associated with liver, kidneys, CNS damage

25
Q

Amantia phalloides and Lepiota is associated with?

A

liver failure

26
Q

Amanita smithiana associated with?

A

renal failure

27
Q

Loxosceles - Brown Recluse Spider causes

A

Dermonecrosis
Painless bite, firm skin lesion, blister, eschar
fever, chills, n/v, arthralgias

28
Q

Lacrodectus - Widow Spiders

A

Pinprick bite, pain spreads fast, muscle cramps

HTN, tachy/tachy, n/v, HA