total pain Flashcards

1
Q

If patient is Fully active, able to carry on all predisease performance without restriction, what is his/her ECOG score?

A

0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

If patient is Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light housework, office work, what is his/her ECOG score?

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

If patient is Ambulatory and capable of all self-care but unable to carry out any work activities; up and about more than 50% of waking, what is his/her ECOG score?

A

2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

If patient is Capable of only limited self-care; confined to bed or chair more than 50% of waking hours, what is his/her ECOG score?

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

If patient is completely disabled, cannot carry out any self-care, totally confined to bed/chair, what is his/her ECOG score?

A

4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

If patient is dead, what is his/her ECOG score?

A

5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is palliative care?

A

An approach which focuses on improving QOL of patients suffering from life-limiting illness
By providing relief from physical, emotional and spiritual suffering

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Principles of palliative care

A

Providing relief from distressing symptoms through early identification, assessment and treatment
Affirming life and regard dying as a normal process
Intending to neither hasten nor postpone death
Integrating psychosocial, emotional and spiritual aspects into holistic care of patient
Supporting family and caregivers during patient’s illness and after patient’s death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which medication route is most preferred?

A

Subcutaneous route also preferred as less invasive compared to IV or IM routes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Drug dosages have to be adjusted in a palliative patient due to:

A

impacted drug metabolism and elimination due to deterioration of patient’s liver and renal function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is Off-label prescription?

A

when prescribed a drug that is approved to treat a condition different than your condition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When is the use of an off-label prescription?

A

positive effects on symptom control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Example of off-label prescription

A

Hyoscine Butylbromide (Buscopan)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dimensions of pain

A

Physical, psychological, social, spiritual

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pain assessment SOCRATES SMM

A

Site
Onset
Characteristics
Radiation
Associated factors (any other symptoms)
Time
Exacerbating and relieving factors
Severity
Sleep/Function
Mood (Does the pain affect your mood?)
Meaning (What does the pain mean to you?)
Use numeric scale / faces rating scale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Causes of pain (Physical)

A

Nociceptive
Neuropathic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is nociceptive pain?

A

Pain from tissue injury (lacerating, stinging, heavy, suffocating)

Somatic: tumour invasion of bone, joint, muscle or connective tissue
Visceral (e.g. bowel obstruction, liver infiltration or compression of vital organs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is neuropathic pain?

A

Pain from nerve injury (usually followed after nociceptive); (numbness, pins and needles, burning, aching, throbbing, pulling) e.g. if patient has left iliac artery stenosis, tumours pressing on spine, lots of nerves

Peripheral: tumour compression of peripheral nerves
Central: multiple sclerosis, stroke

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Social causes of pain

A

Loss of family role
Restricted social activities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Psychological causes of pain

A

Anxiety
Equating pain relief (morphine) with dying
Sense of inevitability of future severe pain
Reminder of ill role
Anger, despair and hopelessness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Spiritual causes of pain

A

Loss of sense of purpose and identity
Feeling of being punished

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Pharmacotherapeutic Intervention basic principles (by mouth)

A
  • the least invasive and safest method.
  • reserved for those not able to take orally
  • unable to absorb drugs via the gastrointestinal tract.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Pharmacotherapeutic Intervention basic principles (by clock)

A
  • most oral analgesics act only for 4 hours or less,
  • should be prescribed 4 hourly to achieve therapeutic effects.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Pharmacotherapeutic Intervention basic principles (by WHO’s pain ladder)

A

dose must be titrated until:

  • the maximum recommended dose is reached
  • the pain is relieved
  • or the patients experience serious side
24
Q

WHO’s pain ladder (STEP 1)

A

Non-opioids e.g. paracet, NSAIDs, COX-2 inhibitors, +/- adjuvant analgesic

25
Q

WHO’s pain ladder (STEP 2)

A

Weak opioids e.g. tramadol, codeine +/- adjuvant analgesic

26
Q

WHO’s pain ladder (STEP 3)

A

Immediate release:
Morphine solution
Oxycodone Methadone

Controlled release:
Morphine Sulphate Tab
Oxycontin
Transdermal Fentanyl

27
Q

Examples of adjuvant analgesics

A

Tricyclic antidepressants
Anticonvulsants
Topical
Steroid

28
Q

(Adjuvant analgesics) Example of anticonvulsants

A

Gabapentin
Pregabalin

29
Q

(Adjuvant analgesics) Example of topical

A

Lignocaine

30
Q

(Adjuvant analgesics) Example of steroid

A

Dexamethasone

31
Q

Morphine Forms of administration

A

Liquid
- Mist morphine solution (1mg/ml)
- Oramorph morphine syrup (2mg/ml)
- RA-morphine solution (1mg/ml)

Tablet (cannot be cut/crushed)
- Morphine sulphate (sustained-release) tablet, aka MST (10 or 30mg tablets)

Injectable
- Per ampoule morphine (10mg/ml) given via SC or IV

32
Q

Side effects of Morphine

A

Constipation (To prescribe lactulose)
N&V (Give antiemetics)
Fatigue, drowsy
Urine retention
Addiction
Vertigo, confusion, headaches
Itchy skin/rash
Poor appetite
Muscle stiffness
Low energy (sign of low BP)
Allergic rxn

33
Q

Unintended side effects

A

Morphine toxicity (should be monitored closely - this should NOT happen)

34
Q

Mist morphine onset of action, maximal effect, duration of action

A

30 min, 60 min, 4-6 hrs

35
Q

MST onset of action, duration of action

A

1-2hrs, 8-12hrs

36
Q

Morphine (SC) onset of action, maximal effect, duration of action

A

15 min, 10-20 min, 4-6 hr

37
Q

Morphine (IV) onset of action, maximal effect, duration of action

A

5 min, 10-20 min, 4-6 hr

38
Q

Common side effects of morphine

A

constipation, N&V, sedation and confusion

39
Q

Morphine toxicity signs

A

Myoclonic jerks (rapid muscular contraction and relaxation)
Pinpoint/constricted pupils (miosis)
Respiratory depression

40
Q

Fentanyl is a safe, strong opioid in patients with ____ (medical condition)

A

Moderate to severe renal failure

Fentanyl is opioid of choice in patients with moderate to severe liver failure or cirrhosis

41
Q

When using fentanyl, caution is required when: (hint: renal)

A

!! Caution required when estimated creatinine clearance < 30 ml/min whether or not patient is on dialysis

42
Q

Which is more potent - fentanyl or morphine?

A

Fentanyl

43
Q

Indications of fentanyl

A

When oral intake not possible (N&V)
Difficult compliance to oral morphine
Patient develops side effect or toxicity of morphine
Severe constipation with morphine
Renal/liver impairment
Patient preference (averse to morphine)

44
Q

Transdermal Fentanyl Patch dosages available

A

12mcg/hr
25mcg/hr
50mcg/hr

45
Q

The nurse is preparing to administer transdermal fentanyl patch to Mr. Lee and wants to administer only half of the patch. How should she split the patch?

A

Tear away half of the plastic backing if only 6mcg fentanyl ordered, do NOT cut

46
Q

The nurse is preparing to administer transdermal fentanyl patch to Mr. Lee. Why shouldn’t she cut the patch?

A

Risk of fatal opioid toxicity to patient and to nurse, dosage of fentanyl is also regulated and needs to be reported to MOH

47
Q

Maximal effects duration of transdermal fentanyl

A

8-12 hrs

48
Q

Residual effect of transdermal fentanyl after removed

A

8-12 hrs

49
Q

Injectable fentanyl dosages

A

100mcg/2ml
500mcg/10ml

50
Q

Side effect of fentanyl

A

Similar to morphine, but less constipation

51
Q

Usual transdermal fentanyl dose given initially

A

6cmg/hr every 72 hrs (use half 12 mcg/hr patch)

52
Q

Usual Subcutaneous fentanyl dose given initially

A

10 mcg/hr (0.2ml/hr)

53
Q

Drug conversion from Morphine to Transdermal Fentanyl Patch (IMPORTANTTTT)

A

Easiest way is to use conversion factor 2.4

E.g. Morphine syrup to fentanyl patch
Morphine syrup 5mg 4 hrly = Total morphine dose 5*6 = 30mg
Fentanyl requirement = 30/2.4 = 12.5mcg/hr

E.g. Fentanyl to morphine syrup
* Patient on Fentanyl 25mcg/hr patch who need to convert to Morphine syrup:
* Fentanyl 25mcg x 2.4 = 60mg Morphine (total daily dose [24hrs])
* 60mg/24hrs=2.5mg (per hour) x 4
-> Morphine syrup 10mg q4H

54
Q

Guide to the use of opioids (3 main points)

A
  • educate pt/caregiver in use of opioid
  • advise about common side effects
  • empower caregiver to manage side effects
55
Q

Non-pharmacotherapeutic intervention by healthcare team

A

Radiotherapy
Palliative surgery
PT/OT
Transcutaneous electrical nerve stimulators (TENS)

56
Q

Non-pharmacotherapeutic intervention not necessarily by healthcare team

A

Massage therapy
Acupuncture
Music/art therapy
Namaste?

57
Q

What are the components of namaste care?

A

Honouring spirit within
Presence of others
Life Story
Sensory stimulation
Enable people to be themselves
Meaningful activity
Food treats & hydration
Family meetings
Comfort & pain management