ToRCH pd Kehamilan & Neonatus Flashcards

1
Q

Kepanjangan ToRCH?

A

Toxoplasma, Rubella, Cytomegalovirus, Herpes simplex

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2
Q

Penyakit yg terdeteksi oleh ToRCH?

A
  1. Sifilis
  2. Hepatitis B
  3. HIV
  4. Enterovirus
  5. Epstein-Barr virus
  6. Varicella zooster virus
  7. Human parvovirus
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3
Q

3 kelompok infeksi penting pada kehamilan?

A
  1. Genital tract infection
  2. Urinary tract infection
  3. Infeksi transplacental
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4
Q

Sebutkan contoh genital tract infection!

A
  1. Herpes
  2. Sifilis
  3. Streptococcus
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5
Q

Sebutkan contoh infeksi transplasental!

A
  1. Rubella
  2. Cytomegalovirus
  3. Toxoplasmosis
  4. Sifilis
  5. HIV
  6. parvovirus
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6
Q

Mengapa dilaksanakan pemeriksaan ToRCH?

A

Skrining kehamilan dan newborn thdp peny. yg dapat menyebabkan cacat lahir (tidak selalu)

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7
Q

Kapan/siapa yg perlu?

A
  • wanita yg akan hamil
  • sedang hamil
  • curiga sakit saat hamil
  • bayi lahir dgn ibu terinfeksi aktif
  • bayi lahir abnormal (diduga krn ToRCH)
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8
Q

Bahan sample ToRCH?

A

Ibu: darah vena
Fetus: amniocentesis (cairan amnion), cordocentesis (umbilikus)
Neonatus: darah tumit, cairan lain (sesuai manifestasi)

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9
Q

Defek karena toxoplasmosis

A
  • microcephaly/hydrocephaly
  • kalsifikasi cerebral menyebabkan EPILEPSI dan kerusakan CEREBRAL
  • chorioretinitis
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10
Q

Defek pd rubella?

A
  • retardasi mental, microcephaly
  • katarak
  • congenital heart disease
  • deafness
  • hepatosplenomegaly dengan trombositopenia
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11
Q

Defek pd Cytomegalovirus

A
  • mati
  • hepatosplenomegaly dan jaundice
  • trombositopenia
  • microcephaly
  • hidrosefalus
  • chorioretinitis
  • atrofi optik
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12
Q

Defek HSV?

A
  1. Herpes neonatorum - encephalitis > 50%

2. Residual neurological damage (1/3)

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13
Q

Dx toxoplasma?

A

+ IgM anti toxoplasma

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14
Q

Obat yang mencegah toxoplasma menembus placenta?

A

Spiramycin

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15
Q

Penyebaran toxoplasmosis kongenital?

A

Penularan infeksi maternal

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16
Q

Efek toxoplasmosis kongenital trimester 1

A

Abortus, fetal death

17
Q

Efek toxoplasmosis kongenital trimester 2 dan 3

A

Defek kongenital