Topic 7/8 Flashcards
Describe the differences in the structure of a myelinated sensory neuron and a myelinated motor neuron (3)
In sensory neuron, dendron is longer
in sensory neuron dendron is myelinated
In sensory neuron axon is shorter
explain the electrical changes in an axon when stimulated by a nerve impulse (4)
potential difference across axon changing
due to increased permeability to sodium ions (volt gates open)
sodium ions cause depolarisation
potassium channels then open
potassium ions cause repolarisation of the membrane
Explain how conduction of nerve impulses will be affected if the following membrane proteins are damaged (6) 1 - Acetylcholine receptors 2 - Voltage-gated sodium ion channels 3 - Voltage-gated potassium ion channels 4 - Calcium ion channel
1 - if Acetylcholine receptors on post-synaptic neuron affected, post-synaptic neuron will not depolarise
2 - if Voltage-gated sodium ion channels affected, no depolarisation of axon
3 - if Voltage-gated potassium ion channels, no repolarisation of axon, no propagation of action potential
4 - if Calcium ion channels affected, vesicles in pre-synaptic neuron will not fuse with pre-synaptic membrane, neurotransmitter wont be released
Explain why there is a difference in the velocity of a myelinated neuron’s nerve impulse and an unmyelinated one (5)
Schwann cells cover axon of myelinated neuron
Schwann cells provide insulation
depolarisation occurs at nodes of Ranvier
Saltatory conduction depolarises part of a neuron not whole one
impulse jumps from node to node
describe and explain the sequence of events that occur at the synapse after a neurotransmitter has been released (5)
Diffuses across cleft
binds to receptors on post-synaptic membrane
causes it to depolarise
if depolarisation is sufficient enough, action potential is set up in post-synaptic membrane
neurotransmitters that are not taken up by the post-synaptic membrane are digested by enzymes in the cleft
Spatial summation allows multiple impulses from various neurons to meet at one neuron and continue to the next as one impulse
in which region is the hypothalamus found (1)
forebrain
State the functions of these regions of the brain (4)
1 - cerebral hemisphere
2 - cerebellum
3 - medulla oblongata
1 - cerebral hemisphere, initiating and controlling voluntary muscle movement
2 - cerebellum, coordinating skeletal muscle movement, balance and posture
3 - medulla oblongata, controlling heart and breathing rate
Describe the role of ATP in the contraction of a muscle fibre (5)
myosin slides along actin to contract muscle fibre
ATP binds to myosin head causing cross-bridge between actin and myosin to break
ATP hydrolyses to ADP and Pi releasing energy, causing myosin head to reset
myosin head binds to actin forming a cross-bridge
Pi is released from myosin head
ATP also transports Ca ions back into sarcoplasmic reticulum
Compare and contrast the properties of the slow and fast twitch cycle
Property - Slow twitch - Fast twitch Myoglobin - more - less mitochondria - many - few Glycogen - less - more capillaries - many - few Myosin ATPase activity - low - high fibre diameter - small - large Creatine phosphate - low high
explain changes when calcium ions bind to molecules in myofibrils (4)
myosin heads can bind to binding sites
myosin changes shape
actin filaments slide over the myosin, causing sarcomeres to shorten
ATP is hydrolysed releasing ADP and Pi
Explain how the blood pH of a sprint is returned to normal after a race (5)
Low pH due to acid in blood
lactate taken to liver
More oxygen has to be inhaled than normal
used to convert lactate back into pyruvate with production of reduced NAD
Pyruvate converted to glucose
chemoreceptors detect change in pH, increased rate
in genetic modification how does addition of chemical cause human gene to be switched on (3)
Chemical could be transcription factor
interaction at bacterial cell surface membrane
the transcription factor is activity
advantage of injecting chemicals into veins rather than arteries
Larger lumen
thinner wall so easier to penetrate
bp is low so less damage to vein
cell that links rod cell to sensory neuron (1)
Bipolar neuron
explain why only one restriction enzyme is used for genetic modification (3)
cuts a specific sequence of bases
generates complimentary sticky ends
easier to join together
suggest why FMRI is considered better than CT for studying brain function (2)
it views brain activity directly
safer as it does not use x rays
sees brain activity over a period of time
how is NAD formed in electron transport chain (3)
due to reduced NAD releasing electrons
electrons go to carriers
H+ moved into inner membrane space
explain link between ATP and H+ in electron transport chain (3)
H+ pass through ATP synthase
H+ pass down electrochemical gradient
Energy is released to join ADP and Pi
compare and contrast CT and MRI for studying brain structure (6)
Image resolution is higher in MRI and lower and CT
CT can only identify larger structures, MRI can identify small ones
MRI uses magnetic fields, CT uses xrays
MRI is safer than Xrays but is louder
both give 2D/3D images
MRI is more expensive than CT
Suggest why pupils appear black (1)
pigment at the back of the eye absorbs light
explain why panting generates heat (2)
panting involves muscle contractions
muscle contraction requires respiration which releases energy
explain the role of negative feedback in the panting response of dogs (5)
Blood temperature is kept in a state of homeostasis
thermoreceptors detect changes in temperature
thermoreceptors send nerve impulses to thermoregulatory centre
if blood temperature increases, TC sends nerve impulses to increase panting
panting causes blood temperature to fall
once normal blood temp is reached, impulse to TC stops and panting stops
Describe how FMRI can be used in an investigation (3)
conduct FMRI scan while someone is engaged in a cognitive activity
indicates areas with high blood flow
lit up areas indicate higher levels of brain activity
When a muscle fibre contracts what happens to the number of myosin heads (1)
stays the same
What does the binding of calcium ions to troponin do (1)
expose myosin bindings sites
describe how the arrival of nerve impulse at synapse releases neurotransmitters (3)
Ca2+ enters synaptic knob
vesicles contain neurotransmitters
they fuse with presynaptic membrane and neurotransmitters are released by exocytosis
Explain the difference between the structure of a myelinated sensory neuron and myelinated motor neuron (3)
IN SENSORY NEURON
dendron longer
dendron myelinated
axon shorter
explain how the sinoatrial node ensures that oxygenated blood enters the aorta (4)
initiates electrical activity over atria
causes atria to contract
forcing oxygenated blood into left ventricle
electrical activity from SAN received by AVN travel through bundle of HIC
causing left ventricle to contract forcing blood into aorta
explain how twin studies can be used to compare the effects of nature and nurture on human development (4)
monozygotic twins are genetically identical
derived from one egg and sperm
any phenotypic difference is due to nurture
dizygotic twins are genetically different
any phenotypic difference when the environment is the same is likely to be nature