Topic 4 - Natural Selection and Genetic Modification Flashcards

1
Q

What is Charles Darwin’s theory of evolution by natural selection?

A

-Genetic variation exists within a population (This might be because of sexual reproduction or mutations)
-A selection pressure is introduced
-Some organism with advantageous traits are more likely to survive and reproduce
-These organisms are more likely to pass on their genes to the next generation - including the advantageous characteristic
-This repeats over many generations and the frequency of the characteristic increases

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2
Q

Explain how the emergence of resistant organisms supports Charles Darwin’s theory of evolution including antibiotic resistance in bacteria

A

Bacteria are resistant when they are not able to be killed by antibiotics which were previously used as cures against them.

-Bacteria reproduce at a rapid rate
-Mutations can cause variation in a population of bacteria, with some being more resistant to antibiotics
-Antibiotics are a selection pressure as the less resistant bacteria die
-Those with antibiotic resistance may survive, can reproduce and pass on the advantageous gene
-The population of antibiotic resistant bacteria increases
-Therefore, the presence of resistant bacteria supports Darwin’s theory of natural selection as the new bacteria have been selected by the environment to have a feature advantageous to survival

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3
Q

Describe the evidence for human evolution based on the first humanoid species

A

The oldest known human ancestor is Ardi (Ardipithecus ramidus) who lived 4.4 million years ago and had both ape and humanoid features; this intermediacy suggests gradual evolution between the two. Hip structure and hand structure suggests stood upright not on all-4s, 350cm3 skull volume. Had different foot structure from chimpanzee but still opposable big toe for climbing.

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4
Q

Describe the evidence for human evolution based on the second humanoid species

A

The fossilised Skelton Lucy (from the species Australopithecus afarensis) dates from 3.2 million years ago. Had 400cm3 skull volume (small like chimp) but non-opposable toe arranged same as modern but more curved. Intermediacy suggests evolution and more than Ardi as greater skull volume.

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5
Q

Describe the evidence for human evolution based on the latest non-homo-sapien humanoid species

A

Homo Erectus fossils discovered by Richard Leakey, species alive between 1.8-0.5 million years ago. Strongly built 850cm3 skull volume (greater than previous species but less than 1450cm3 skull volume of Homo sapiens)

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6
Q

How did stone tools develop? How is this evidence for human evolution?

A

Stone tools became more complex, indicating our brains evolved in complexity.
-Homo Habilis used basic pebble tools 1.5 million years ago made by smashing rocks together.
-In the late Stone Age homo sapiens and neanderthals used pointed arrowheads, spears and hooks.

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7
Q

How can stone tools be dated?

A

-By radiometric carbon dating. If a nice-living material is found with a tool we can date the natural radioactive decay of an isotope of carbon on it to estimate how long ago the organism the material was from lived.

-By stratifying rock layers. We can date once-living fossils from the same rock layer as the tool (as each layer of sediment must have been formed at the same time) to estimate when the tool was formed.

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8
Q

What kind of structure is the pentadactyl limb?

A

A homologous structure as, while the structures of different organisms may appear superficially different, they have the same underlying structure.
The pentadactyl limb is shared between many different species.

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9
Q

Explain how the study of the pentadactyl limb provides evidence for evolution.

A

As a wide variety of vertebrates share the pentadactyl limb as they all evolved from a common ancestor which had it. However, divergent evolution then took place in which each of these species evolved to fill a specific niche. (Different mutations –> different environments –> different features which are beneficial there and therefore survive + reproduce)

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10
Q

Describe how genetic analysis has led to the suggestion of the three domains rather than the five kingdoms classification method

A

Before domains were made kingdoms were the largest group. Bacteria and archaea were in the prokaryote kingdom.
Then, after we developed methods to make molecular observations (analyse genes)) we realised that bacteria and archaea aren’t as similar as we thought: so the 3 domains were made of bacteria, archaea and eukarya (everything with a nuclei)

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11
Q

List the order of classification from most closely related to least diversity between individuals

A

Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species

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12
Q

Define selective breeding

A

When humans choose certain organisms to breed together because they have useful characteristics

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13
Q

Explain how you might go about selective breeding.

A

-Genetic variation exists.
-Select 2 of the same species that have the desirable characteristic and have them breed together.
-Then breed together the offspring with the greatest of this characteristic.
-Eventually the majority of the population should have this characteristic.

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14
Q

Explain the problem that can arise from selective breeding.

A

This can result in inbreeding as breeding those with similar desirable characteristics mean it is likely that they are closely related. This results in reduction of the gene pool as the number of different alleles reduce. This means if there is a selection pressure the chance of a few organisms have a survival advantage and not dying is reduced so the species may become extinct.

The small gene pool can also lead to a greater chance of genetic defects as recessive characteristics are more likely to present.

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15
Q

How is tissue culture performed?

A
  • Using tweezers remove a piece of tissue from a fast-growing region of the plant you would like to clone
    -Using aseptic technique, place the tissue on a growth medium containing necessary hormones and nutrients
    -Once the tissue has developed enough (e.g. produced shoots and roots) it can be transferred to compost for further growth.
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16
Q

What are the advantages of tissue culture?

A

-Can produce lots of offspring with a specific desirable characteristic
-e.g. Increasing the number of crops resistant to bad weather can increase crop yields
-Can help extremely endangered species or even bring back species that have become extinct.

17
Q

What is genetic engineering?

A

A process which involves modifying the genome of an organism to introduce desirable characteristics.

18
Q

Describe the main stages of genetic engineering

A

-Genes from chromosome are cut out using restriction enzymes
-The same restriction enzymes are used to cut the vector ( a DNA molecule that is used as a vehicle to carry a particular DNA segment into a host cell) into which the genes will be placed
-Ligase enzyme is used to attach the sticky ends of the gene and the vector together, to produce a recombinant gene product. The vector is placed in another organism at an early stage in development so the desired gene moves int its cells and cause the organism to grow with the desired characteristics.
In plants the vector is put into meristematic cells which can then produce identical copies of the modified plant.

19
Q

What are the advantages of genetic engineering?

A
  • It can be very useful in medicine to mass produce certain hormones in micro-organisms.
  • In agriculture it can be used to improve yields by:
    -Improving growth rates
    -Introducing modifications that allow the crops to grow in different conditions
    -Introducing modifications that allow plants to make their own pesticide or herbicide
  • Greater yields can help solve world hunger (which is increasingly becoming a bigger issue with population growth)
  • Crops with extra vitamins can be produced in areas where they are difficult to obtain
20
Q

What are the disadvantages of genetic engineering?

A

*GM crops might have an effect on wild flowers and therefore insects
- GM crops are infertile and these genes could spread into wild plants, leading to infertility in other species
-Growing with herbicides and pesticides can kill insects and other plants, which would reduce biodiversity - which can affect the entire ecosystem
* People are worried that we do not completely understand the effects of GM crops on human health
* Genetic engineering could lead to genetically engineered humans. This may result in people using the technology to have designer babies which could be seen as immoral, messing with nature and trying to make certain characteristics extinct
* They pose a selection pressure which could lead to increased resistance in other species, creating evolved weeds and pests

21
Q

Describe the introduction of genes for insect resistance from Bacillus thuringiensis (Bt) into crop plants

A

Bacillus thuringiensis is a bacteria which produces toxins that kill insect larvae.
We cut genes out from the bacteria using restriction enzymes and re-insert them into the crop using ligase, this is to increase insect resistance.
The crop will then produce the toxin so that any insects that eat the crop die.

22
Q

State the advantages and disadvantages of Bacillus thuringiensis in crop plants

A

Pro:
-This increases the crop yield and therefore any profits
Cons:
-We don’t know if the toxin has any effect on human health
-Killing insects results in a loss of biodiversity, which can affect the entire ecosystem

23
Q

Evaluate the advantages and disadvantages of the agricultural solution (to the demands of a growing human population) of fertilisers

A

Pros:
-Provide useful nutrients (nitrates and phosphates) to plants, *making them more resistant to environmental conditions and *able to grow faster and larger - resulting in increased crop yields
Cons:
-Excess fertiliser can often run off into rivers, killing fish and other wildlife and affecting biodiversity

24
Q

Evaluate the advantages and disadvantages of the agricultural solution (to the demands of a growing human population) of biological control

A

(Biological control is the use of certain species to control the population of other species)
Pro:
-The aphid killer wasp has been used successfully to control aphid populations - which feed on fruit crops, more crops for humans
Con:
-This reduces biodiversity which affects the whole ecosystem

25
Q

What are the advantages of selective breeding?

A
  • Is possible to greatly increase the yield of a particular crop by selectively breeding only individuals that produce higher quality or a larger mass of food
  • Individual plants or animals can be bred to be resistant to a particular disease, which could increase crop/food yield
26
Q

What are the disadvantages of selective breeding?

A

-Can result in inbreeding because of reduced gene pool. This means that health problems are more likely as recessive alleles are more likely to present. Also means if selection pressure introduced it’s less likely any of the species would survive + all are susceptible to same diseases
-May be considered unethical and lead to selective breeding in humans