topic 4 : exchange and transport Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

what is simple diffusion

A

passive transport, movement of substances from an area of high to low concentration. in the phospholipid bilayer, small/non-polar molecules can go through.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is facilitated diffusion?

A

diffusion that takes place through carrier protein or protein channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is active transport

A

movement of substances from an area of low to high concentration (against the concentration gradient). This is helped with ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

two types of active transport

A

endocytosis : movement of large molecules into the cell by fusing a vesicle with the cell surface membrane

exocytosis : movement of large molecules out of the cell by the fusing of a vesicle (which contains the substances) with the cell surface membrane (requires ATP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

describe and explain the structures of the fluid mosaic model

A
  • phospholipid bilayer (non polar tail is away from the water)
  • phospholipids can move aorund (thats why the layer is fluid)
  • proteins in cell membrane (peripheral and integral)
  • cholesterol : stability
     peripheral proteins are used for structural purposes
     integral proteins used for transporting minerals
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Charged particles and large particles need to be moved by what?

A

integral proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

describe the process of inhalation

A
  • interconstal muscles contract
  • diaphram flattens (contract)
  • volume in thorax increases
  • pressure decreases lower than the atmospheric pressure
  • air forced in down the conc gradient
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

describe the process of exhalation

A
  • intercostal muscles relax
  • diaphragm relaxes
  • volume of thorax decreases
  • the pressure will increase (higher than the atmospheric pressure)
  • air forced out down the conc gradient
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how are alveoli adapted to gas exchange

A
  • large surface area (maximise gas exchange - short diff dist)
  • thin/flat epithelial cells - short diffusion distance
  • ventilation - breathing in and out will constantly remove the co2
  • high capillary network : oxygenated blood constantly carried out - maintian steep conc gradient
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how are insects adapted for gas exchange

A
  • spiracles : closing the spiracles by using sphincter muscles (this controls the amt of H2O being released)
  • trachae are branched (into traecheoles - increase sa:vol ration)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how do insects do gas exchange

A

o Spiracles are openings in the exoskeleton allowing gas exchange – the opening and closing of them are controlled by sphincter muscles to prevent water loss

o Oxygen diffuses into the spiracles, down the trachea (the trachea is lined with chitin making it impermeable preventing gas exchange here and also prevents the trachea collapsing)

o Oxygen then diffuses into tracheoles which are permeable, so gas exchange occurs here with the muscle fibres

o Sometimes water builds up at the bottom of tracheoles (dissolve the oxygen)
then the oxygen can go to the muscle fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what happens if there is less gas exchange in the insect

A

less gas exchange -> anaerobic respiration -> lactic acid builds up in the muscles

  • the water potential in the muscles will be lower than in the tracheoles
  • so water moves into muscles by osmosis
  • then respiration/gas exchange will resume as normal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how do fish adapt to gas exchange

A

lamellae : thin branches - large surface area and small diffusion distance (have rich blood supply -> maintain conc grad)

countercurrent flow : maintain steep conc grad , blood flows in opposite directions- blood always meets water that has a high conc in o2

overlapping gill filaments - slow down flow of water (more time for gas exchange)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how do fish do gas exchange

A

o Gills are made up of filaments called lamellae – water continuously moves over the gills keeping them spread out to increase the SA and also prevent the gills sticking together

o Floor of the mouth opens the operculum (gill flap) closes

o The mouth will close and this causes the floor of the mouth to raise and increase the pressure

o The increased pressure will force open the operculum and water is forced over the gills

o Countercurrent exchange system: blood and water flow in opposite direction to maintain the steep conc gradient over the entire gill filament

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how do plants do gas exchange

A

when conditions are favorable for photosynthesis, K+ ions move into the guard cells by active transport
- this makes water move into the guard cells by osmosis
- arrangement of cellulose in cell wall results in bending of guard cells (stomata opens) [the inner wall is rigid and it resists the expansion, so they become curved]

when conditions not favourable, K+ ions are move out of guard cells -> water leaves by osmosis, guard cell becomes flaccid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how do plants adapt for gas exchange
(normal plants and woody plants)

A
  • leaves provide a large surface area
  • spongy mesophyll cells are irregularly shaped (large surface are) and have thin walls (small diffusion distance)
  • walls of mesophyll are moist (so they can absorb their necessary gases)
  • stomata :

in woody plants :
- loosely arranged cells with air spaces
- they link the inner tissues of woody structures like tree trunks to the outside so that respiration can take place.
- they can also form roots for G.E with the soil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is a double circulatory system

A

blood goes through the heart two times

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are the advantages of having a double circulatory system

A
  • oxygenated and deoxygenated blood dont mix and maintains conc grad
  • blood pressure to body tissues is higher
  • blood pressure to lungs is lower, this increases the time for gas exchange [avoid damage to the capillaries]
  • organisms can have larger bodies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is systematic circulation

A

oxygenated blood to tissues, then return deoxygenated blood to the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is pulmonary circulaton

A

circuit between heart and lungs - lower pressure due to capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what does the atrioventricular valve do

A

bicuspid (left) and tricuspid (right) prevent the backflow into the atria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what do the semilunar valves do

A

separate artieries from ventricles (where blood leaves the heart from)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what do the tendinous chords do (is attached to the AV valves)

A

prevent AV valves turning inside out due to pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what does the septum help with

A

it prevents the mixing of blood because it separates the right and left side

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

what is the function of coronary artieres

A

they branch off the aorta and deliver blood to the heart by capillaries (deliver O2 and C6H12O6)

26
Q

why is the cardiac muscle thicker on the left side?

A

Cardiac muscle is thicker on the left side compared to the right because higher pressure is needed to pump the blood further to all the tissues in the body

27
Q

what does myogenic mean

A

it initiates its own contractions (doesn’t need the nervous system to make it contract, it contracts on its own)

28
Q

what does the sino atrial node do (SAN)?

A

sends out waves of depolarisation/excitation across the atria

29
Q

what does atrial systole mean

A

During atrial systole the left and right atria contract at the same time and push blood into the left and right ventricle, respectively.

30
Q

what is ventricular systole

A

contraction of ventricles

31
Q

what is diastole

A

relaxing of the atria and ventricles

32
Q

how does the cardiac cycle work

A
  1. Sino atrial node (SAN) sends out a wave of depolarisation/excitation across the atria
  2. Atrial systole: atria contract and it forces the opening of the AV valves and blood flows into the ventricles
  3. AVN sends out another wave of depolarisation down the bundle of his (in the septum)/ and up the purkinje fibres
  4. Ventricular systole: ventricles contract from the bottom up. The SL valves open and the AV valves close
  5. Cardiac diastole: atria and ventricles both relax, pressure in the heart decreases. The SL valves will close to prevent backflow of blood
33
Q

feedback loop with blood pressure

A

INCREASE IN BLOOD PRESSURE
- baroreceptor send action potential more than usual to brainstem
- med obl stimulates the parasympathetic neurons and inhibit sympathetic
- release acetylcholine, which bind to receptor on SAN.
- lower HR (vasodilation)

DECREASE IN BP
- baroreceptors send action potential less than usual to brain stem
- med obl stimulate sympathetic and inhibit parasympathetic
- release noradrenaline (attach to receptor on SAN)
- increase HR

34
Q

ECG diagram (explain)

A

P - electrical activity of atrial systole
P-> Q : time signals travel from SAN to AVN (atria contracting)
QRS complex - ventricular systole
S->T : plateu in action potential (ventricles contract and push blood out)
T - ventricular diastole
T->P - filling time of ventricles with blood (passive blood flow)

35
Q

what are chemoreceptors

A

measure chemica; composition of blood (O2,CO2 etc)

36
Q

features of arteries

A
  • carry oxygenated blood
  • tunica layers : intima (elastic tissure), media (smooth muscles), externa (collagen)
  • withstand pressure with thick intima
37
Q

features of veins

A
  • deoxygenated blood
  • semilunar valves to ensure one-way flow of blood
  • wide lumen, thin walls
38
Q

features of capillaries

A
  • single layer of endothelium surrounding lumen
  • tiny : slow blood flow so more time for diffusion
39
Q

what are the functions of blood

A
  • transport
  • defence against pathogens
  • formation of lymph and tissue fluid
40
Q

what is the function of plasma

A

carries water soluble molecules (digested food, excretory products, hormones). also transfers heat energy.
- also contains platlets

41
Q

what is the function of erythrocytes

A

biconcave shape, no nucleus and contains haemoglobin

42
Q

what is the function of leukocytes

A

white blood cells
- granulocytes (lobed nuclei) and angranulocytes

43
Q

what are some examples of leukocytes

A
  • neutrophils and monocytes : engulf and digest pathogens by phagocytosis
  • eosinophils : response against parasites
  • basophils : inflammation and allergic reaction
  • lymphocytes : play a role in the specific immune system
44
Q

what is tissue fluid and what is its function

A

as blood circulates the body, plasma leaves the blood vessels
- travels into body tissues delivering food, oxygen and hormones
THIS IS KNOWN AS TISSUE FLUID

  • function : collect waste products from cells
45
Q

what is lymph

A

10% of remaining tissue fluid that remains is lymph

46
Q

what are the characteristics of lymph vessels and what are the function of lymph nodes

A
  • valves to stop backflow
  • muscular walls - contract and force lymph forward
  • lymph nodes have lymphocytes and these destroy any pathogens in the lymph
47
Q

what is the importance of lymphatic system

A

The lymph system is an important part of our immune system. It plays a role in: fighting bacteria and other infections. destroying old or abnormal cells, such as cancer cells

48
Q

describe the lymphatic system

A
  • hydrostatic pressure forces fluid out of the capillaries (plasma with the nutrients)
  • this is the tissue fluid which contains all the dissolved substances in blood
  • AT THE ARTERIAL END, HYDROSTATC PRESSURE IS GREATER THAN ONCOTIC PRESSURE ( caused by water potential water move into blood by osmosis)
  • AT THE VENOUS END, ONCOTIC PRESSURE GREATER THAN HYDROSTATIC PRESSURE - most tissue fluid is reabsorbed
  • tissue fluid that isn’t reabsorbed drained into the lymphatic system and known as lymph
49
Q

difference between hydrostatic and oncotic pressure

A

hydrostatic : force push fluid out of blood
oncotic : push fluid in blood

50
Q

what is the importance of blood clotting

A
  • prevent blood loss + entry of disease-causing microorganisms from damaged blood vessels
  • framework for repair (doesnt let anything get in and skin is made as before)
51
Q

how does a blood clot occur

A
  • platlets become adhesive after reacting to substances on damaged skin (eg. collagen)
  • platelets form a plug and release clotting factors including thromboplastin
  • thromboplastin catalyses conversion of prothrombin (sol protein) to thrombin (sol enzyme)
  • thrombin converts sol fibrinogen to insoluble fibrin (forms mesh [scab] over wound)
  • sticky platlets and blood cells get trapped in mesh – clot formed
  • clotting factors reinforce the clot - protect skin and vessels underneath
52
Q

what is vascular spasm

A

blood vessels constrict to reduce the blood loss

53
Q

what is atheroscleerosis

A

hardening of arteries caused by an atheroma (plaque)

54
Q

what is an atheroma

A

build up of fatty deposit, mainly low density liipoprotein (LDL).
- forms in endothelium (the lining of blood vessel)
- hard fatty substance

55
Q

how does atherosclerosis develop

A
  • damage to artery lining
  • inflammatory response (WBC to area)
  • buildup of cholesterol
  • this causes atheroma to form
  • calcium salts and fibrous tissue accumulate - form hard plaque
  • artery narrow and wall elasticity reduce
  • blood pressure rises - this can happen again and again
56
Q

effects of atherosclerosis

A
  • aneurysm : bursting of artery
  • raised BP (damaged kidneys/stroke)
  • angina : narrowing of coronary arteries (less blood to heart - chest pain)
  • HEART ATTACK : coronary artery completely blocked (heart doesnt get oxygen)
  • STROKE : interrupt blood supply to brain
57
Q

risk factors of atherosclerosis

A
  • genetics : High bp and cholesterol
  • age (BV lose elasticity)
  • gender (oestrogen reduce buildup of plaque)
  • smoking
  • amt of exercise
  • weight
  • diet : HDL (good cholesterol) and LDL (bad cholesterol)
58
Q

explain how haemoglobin has affinity for oxygen

A

as the partial pressure of oxygen increases, haemoglobin affinity for oxygen also increases.

but!! as more oxygen gets added to haemoglobin, then the affinity decreases (the s curve - dissocation

59
Q

what is the dissociation curve

A
  • s-shaped due to cooperative binding of oxygen to haemoglobin (first molecule makes it easier for others to bind)
  • plateaus because as haemoglobin becomes more saturated, it gets harder for further oxygen molecules to bind
60
Q

what is the bohr’s effect

A
  • effect of CO2 on the oxygen dissociation curve
  • Hb has a reduced affinity for oxygen with an increase in CO2 level
  • O2 is dissociated in respiring tissues
    (beneficial as it is going where it is
    needed)
61
Q

why does foetal haem. have a higher affinity for oxygen than adult

A

maternal and foetal blood runs in a countercurrent exchange system
- difference in affinity so O2 can dissociate from maternal Hb and bind to foetal Hb

62
Q

why is myoglobin and what is its importance

A
  • found in muscles
  • high affinity for oxygen (more than Hb) –> it is unaffected by partial pressure
  • acts as an O2 store - does not release oxygen easily, only when most needed in muscles