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GCSE Biology > Topic 3 Infection and Response > Flashcards

Topic 3 Infection and Response Flashcards

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1
Q

What is a communicable disease?

A

A disease caused by a pathogen which can be passed between animals or plants eg. flu.

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2
Q

What is a pathogen?

A

A disease-causing microorganism e.g.
bacteria.

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3
Q

How do bacteria cause disease?

A

Once inside the body, they divide rapidly by binary fission. They kill cells and produce harmful toxins.

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4
Q

How do viruses cause disease?

A

They invade and reproduce inside living body cells, leading to cell damage.

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5
Q

Give three ways in which pathogens can be
spread

A

● By air - flu, tuberculosis and the common cold are
spread by droplet infection.
● By water - fungal spores in water spread plant
diseases.
● By direct contact - common in plant diseases and
sexually transmitted infections.

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6
Q

Give four ways in which the spread of
pathogens can be reduced

A

● Hygiene - handwashing, disinfectants, tissues.
● Reducing contact with infected individuals -
quarantine.
● Removing vectors - use of pesticides and
insecticides, removal of habitats.
● Vaccination.

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7
Q

Why is it especially important to prevent the
spread of viral diseases?

A

Scientists have not yet developed cures for
many viral diseases.

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8
Q

What is measles?

A

Measles is a serious viral disease that can cause blindness and brain damage. The main symptoms are a fever and a red skin
rash.

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9
Q

How is measles spread?

A

By air - through the inhalation of droplets
from coughs and sneezes.

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10
Q

What is HIV/AIDS?

A

HIV is a virus which attacks and damages the immune system until it can no longer function properly. AIDS is the condition resulting from a long-term HIV infection. There is no cure or
vaccine for HIV/AIDS.

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11
Q

How is HIV spread?

A

Direct sexual contact and the exchange of bodily fluids eg. blood, breastmilk.

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12
Q

How can the spread of HIV/AIDS be prevented?

A

●Use of condoms
● Screening of blood for transfusions
●Not sharing needles
● Bottle-feeding by HIV-positive mothers
●Use of antiretroviral drugs to prevent the
development of AIDS

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13
Q

What is tobacco mosaic virus?

A

A plant pathogen which causes leaf discolouration when cells are damaged. Affected areas cannot photosynthesise, reducing the crop yield. As there is no treatment, farmers grow TMV-resistant crop strains to avoid infection.

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14
Q

How is tobacco mosaic virus spread?

A

Contact between infected and healthy plants. Insects may act as vectors which transfer the virus between different plants.

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15
Q

What is salmonella?

A

A type of bacteria found in raw meat, poultry and eggs. If they enter the body via food poisoning, they can affect natural gut
bacteria.

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16
Q

What are the symptoms of salmonella food
poisoning?

A

● Fever
● Abdominal cramping
● Vomiting
● Diarrhoea
May be fatal in very young or elderly populations due the
risk of dehydration.

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17
Q

How can the spread of salmonella be limited?

A

● Vaccinating animals intended for consumption
● Keep raw meat away from cooked meat
●Disinfect hands and surfaces after contact with
raw meat
● Thoroughly cook meat

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18
Q

What is gonorrhoea?

A

A sexually transmitted bacterial infection caused by unprotected sex with an infected individual. Early symptoms include yellow/green discharge from genitals and painful urination, although it may be symptomless. Its spread can be controlled through the use of antibiotics (no longer penicillin as many strains are resistant) and using condoms.

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19
Q

What is rose black spot?

A

A fungal disease which causes purple or black spots to develop on rose leaves. It reduces the area of the leaf which is available for
photosynthesis and causes leaves to turn yellow and drop prematurely.

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20
Q

How is the rose black spot fungus spread?

A

Fungal spores are spread by the wind
and in water.

21
Q

How can the rose black spot fungus be treated?

A

●Using fungicides
●Destroying infected leaves

22
Q

What is malaria?

A

Malaria is a disease caused by protist pathogens. The disease is carried from host to host by mosquitoes, and the protists enter the human bloodstream when they feed. Symptoms include
fever and shaking, and it may also be fatal in some cases.

23
Q

How can the spread of malaria be reduced?

A

●Using insecticides
●Using insect nets to avoid bites
● Prevent mosquito breeding by removing stagnant
water
● Antimalarial drugs

24
Q

How does the skin prevent pathogens from
entering the body?

A

● Acts as a physical barrier.
● Scab formation after skin is cut/wounded.
● Antimicrobial secretions which can kill pathogens.
●Healthy skin flora compete with pathogens and
act as an additional barrier.

25
Q

How does the respiratory system prevent
pathogens from entering the body?

A

●Nose - has hairs and mucus which trap pathogens.
● Trachea and bronchi - have mucus that traps pathogens. Ciliated cells move mucus to the mouth so it can be swallowed.

26
Q

How does the stomach prevent pathogens
infecting the body?

A

● Secretes hydrochloric acid - kills any pathogens
present.

27
Q

How does phagocytosis protect us against
disease?

A

White blood cells (phagocytes) ingest and destroy pathogens so they cannot infect more cells.

28
Q

How does antibody production protect us
against disease?

A

White blood cells produce antibodies which are
complementary to a specific antigen on a pathogen. The
binding of antibodies to antigens causes pathogens to
clump together, making them easier to destroy. In the case
of a second infection, the correct antibodies can be
produced rapidly, preventing the person getting the same
disease again.

29
Q

How does antitoxin production protect us
against disease?

A

Antitoxins bind to toxins released by pathogens and neutralise them.

30
Q

What is a vaccination?

A

Contains a dead or inactivated form of the pathogen which stimulates white blood cells to produce complementary antibodies to the pathogen. In the case of a second infection, memory cells can rapidly produce the correct antibodies and prevent illness.

31
Q

What is herd immunity?

A

If a sufficiently high proportion of a population are immune to a disease (especially through vaccination), the spread of this disease will be limited.

32
Q

What are the advantages of vaccinations?

A

● They have eradicated many deadly diseases eg.
smallpox.
●Many epidemics can be prevented by
vaccinations.
●Herd immunity protects those who cannot have
vaccinations.

33
Q

What are the disadvantages of vaccinations?

A

●Not guaranteed to work - might not protect
against multiple strains of a pathogen.
●May be side effects or adverse reactions.

34
Q

What drugs are used to cure some bacterial
diseases?

A

Antibiotics - they can kill bacterial pathogens inside the body.

35
Q

How do antibiotics work?

A

Antibiotics eg. penicillin kill bacterial pathogens inside the body, but do not kill human cells. Whilst some antibiotics kill a wide range of bacteria, it is important that the right antibiotic is used for specific bacteria.

36
Q

Why can antibiotics not be used to treat viral
diseases?

A

Antibiotics have no effect on viral pathogens as they live inside thehost’s (human) cells. Therefore, it is difficult to design drugs that would kill the virus and not destroy human cells at the same time.

37
Q

What is antibiotic resistance?

A

Antibiotic resistance occurs when mutations lead to individual bacteria being resistant to an antibiotic. These bacteria are able to survive, reproduce and pass on their alleles, leading to a greater proportion of antibiotic-resistant bacteria. This is concerning as some types of bacteria are becoming resistant to all known antibiotics, so the diseases that they cause cannot be cured.

38
Q

How can we prevent antibiotic resistance?

A

● Avoid overuse and unnecessary use of antibiotics - eg. antibiotics are often used for viral infections.
● Finish antibiotic courses - to ensure all bacteria is
killed.

39
Q

What effect do painkillers have on
infectious diseases?

A

Painkillers can only treat the symptoms but do not kill pathogens.

40
Q

What plant is the heart drug digitalis extracted from?

A

Foxgloves

41
Q

What painkiller originates from a compound
found in willow bark?

A

Aspirin

42
Q

What antibiotic was discovered by Alexander
Fleming from a type of mould?

A

Penicillin

43
Q

What are the four qualities of a good medicine?

A

● Effective
● Safe
● Stable
● Able to be taken in and removed easily

44
Q

What three main factors are tested for when
developing new drugs?

A

● Toxicity
● Efficacy
●Dose

45
Q

How is preclinical testing carried out?

A

In a laboratory - uses cells, tissues and live animals

46
Q

How is clinical testing carried out?

A

Uses healthy volunteers and patients. Firstly, the drug is tested at a low dose on healthy people - then tested on patients and on a larger scale to find the optimum dose. Often, one group receive a placebo (not the test drug) and the other group receive the actual drug, in order to assess its efficacy.

47
Q

What is the difference between a single-blind
and a double-blind trial?

A

In a single-blind trial, only the doctor knows whether the patient is receiving the drug or the placebo. In a double-blind trial, neither the patient nor the doctor knows. Double-blind trials help remove bias on the part of the doctor.

48
Q
A

GCSE Biology (3 decks)

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