Topic 3: Factors influencing the EC and IC compartments, anelectrolite and electrolite components of the blood plasma Flashcards
1
Q
What should be mentioned in this topic?
A
- Factors influencing EC and IC
- Anelectrolite Components of the Blood Plasma
- Electrolite Components of the Blood Plasma
2
Q
Factors influencing EC and IC
A
Osmotic Pressure Molarity Osmolarity Molality Osmolality Oncotic Pressure
3
Q
Osmotic Pressure
A
Measured in kPA
P=CxRxT
P= Osmotic Pressure
C= Conc of dissolved substance R= General gas constant
T= Temperature
P=rxCxRxT
r= Reflection coefficient (r=1, membrane is semipermeable)
4
Q
Molarity
A
Measured in mmol/l
1 mol dissolved anelectrolite in 1L = P of 2.27MPa
5
Q
Osmolarity
A
1 osmol/L = 6x1023 dissolved substance/L
6
Q
Molality
A
Measured in mol/kg
7
Q
Osmolality
A
Measured in 1osmol/kg
- Common index number for the osmotic effect of electrolites and anelectrolites
8
Q
Oncotic Pressure
A
Pressure maintained by proteins and colloid particles
9
Q
Anelectrolite Components of the Blood Plasma
A
Glucose 5 mmol/L Urea 3-10 mmol/L NPN 15-25mmol/L
10
Q
Electrolite Components of the Blood Plasma
A
Cations: Na+ 140 mmol/l K+ 4 mmol/l Mg+ 1.5 mmol/l Ca2+ 1.25 mmol/l
Anions: Cl- 110 mmol/l HCO3- 27 mmol/l Protein 17 mmol/l Phosphate 2 mmol/l Sulphate 1mmol/l Organic acids 4 mmol/l Osmolality calculated on the basis of total electrolyte concentration: 280mmol/kg Osmolality calculated by freezing point depression: 300mmol/kg Difference is the non-ionic osmolality
