topic 3 Flashcards
Surface area to volume ratio
The surface area of an organism divided by its volume
the larger the organism, the smaller the ratio
Factors affecting gas exchange
diffusion distance
surface area
concentration gradient
temperature
Ventilation
Inhaling and exhaling in humans
controlled by diaphragm and antagonistic interaction of internal and external intercostal muscles
Inspiration
External intercostal muscles contract and internal relax pushing ribs up and out diaphragm contracts and flattens
air pressure in lungs drops below atmospheric pressure as lung volume increases
air moves in down pressure gradient
Expiration
External intercostal muscles relax and internal contract pulling ribs down and in diaphragm relaxes and domes air pressure in lungs increases above atmospheric pressure as lung volume decreases
air forced out down pressure gradient
Passage of gas exchange
Mouth / nose -> trachea -> bronchi -> bronchioles -> alveoli
crosses alveolar epithelium into capillary endothelium
Alveoli structure
Tiny air sacs
highly abundant in each lung - 300 million
surrounded by the capillary network
epithelium 1 cell thick
Why large organisms need specialised exchange surface
They have a small surface area to volume ratio
higher metabolic rate - demands efficient gas exchange
specialised organs e.g. lungs / gills designed for exchange
Fish gill anatomy
Fish gills are stacks of gill filaments
each filament is covered with gill lamellae at right angles
How fish gas exchange surface provides large surface area
Many gill filaments covered in many gill lamellae are positioned at right angles creates a large surface area for efficient diffusion
Countercurrent flow
When water flows over gills in opposite direction to flow of blood in capillaries equilibrium not reached diffusion gradient maintained across entire length of gill lamellae
Name three structures in tracheal system
Involves trachea, tracheoles, spiracles
How tracheal system provides large surface area
Highly branched tracheoles large number of tracheoles filled in ends of tracheoles moves into tissues during exercise
so larger surface area for gas exchange
Fluid-filled tracheole ends
Adaptation to increase movement of gases
when insect flies and muscles respire anaerobically - lactate produced
water potential of cells lowered, so water moves from tracholes to cells by osmosis
gases diffuse faster in air
How do insects limit water loss
Small surface area to volume ratio
waterproof exoskeleton spiracles can open and close to reduce water loss
thick waxy cuticle - increases diffusion distance so less evaporation
Dicotyledonous plants leaf
tissues
Key structures involved are mesophyll layers
(palisade and spongy mesophyll)
stomata created by guard cells
Gas exchange in plants
Palisade mesophyll is site of photosynthesis
oxygen produced and carbon dioxide used creates a concentration gradient
oxygen diffuses through air space in spongy mesophyll and diffuse out stomata
Role of guard cells
swell - open stomata
shrink - closed stomata
at night they shrink, reducing water loss by evaporation
Xerophytic plants
Plants adapted to survive in dry environments with limited water (e.g. marram grass/cacti) structural features for efficient gas exchange but limiting water loss
Adaptations of xerophyte
Adaptations to trap moisture to increase humidity -> lowers water potential inside plant so less water lost via osmosis
sunken stomata curled leaves hairs
thick cuticle reduces loss by evaporation
longer root network
Digestion
Process where large insoluble biological molecules are hydrolysed into smaller soluble molecules
so they can be absorbed across cell membranes
Digestion
Process where large insoluble biological molecules are hydrolysed into smaller soluble molecules
so they can be absorbed across cell membranes
Locations of carbohydrate
digestion
Mouth -> duodenum -> ileum
Locations of protein digestion
Stomach -> duodenum -> ileum
Endopeptidases
Break peptide bonds between amino acids in the middle of the chain
creates more ends for exopeptidases for efficient hydrolysis
Exopeptidases
Break peptide bonds between amino acids at the ends of polymer chain
Membrane- bound dipeptidases
Break peptide bond between two amino acids
Digestion of lipids
Digestion by lipase (chemical) emulsified by bile salts (physical)
lipase produced in pancreas bile salts produced in liver and stored in gall bladder
Lipase
Produced in pancreas Breaks ester bonds in triglycerides to form :
monoglycerides glycerol
fatty acids
Role of bile salts
Emulsify lipids to form tiny droplets and micelles increases surface area for lipase action - faster hydrolysis
Micelles
Water soluble vesicles formed from fatty acids, glycerol, monoglycerides and bile salts
Lipid
Micelles deliver fatty acids, glycerol and monoglycerides to epithelial cells of ileum for absorption
cross via simple diffusion as lipid-soluble and non-polar
Lipid modification
Smooth ER reforms monoglycerides / fatty acids into tryglycerides
golgi apparatus combines tryglycerides with proteins to form vesicles called chylomicrons
How lipids enter blood after modification
Chylomicrons move out of cell via exocytosis and enter lacteal lymphatic vessels carry chylomicrons and deposit them in bloodstream
How are glucose and amino acids absorbed
Via co-transport in the ileum
Haemoglobin (Hb)
Quaternary structure protein 2 alpha chains
2 beta chains
4 associated haem groups in each chain containing Fe2+
transports oxygen
Affinity of haemoglobin
The ability of haemoglobin to attract / bind to oxygen
Saturation of haemoglobin
When haemoglobin is holding the maximum amount of oxygen it can hold
Loading / unloading of haemoglobin
Binding/detachment of oxygen to haemoglobin
also known as association and disassociation
Oxyhaemoglobin dissociation curve
oxygen is loaded in regions with high partial pressures (alveoli) unloaded in regions of low partial pressure (respiring tissue)
Oxyhaemoglobin dissociation curve shifting left
Hb would have a higher affinity for oxygen
load more at the same partial pressure
becomes more saturated adaptation in low-oxygen environments
e.g. llamas/ in foetuses
Cooperative binding
Hb’s affinity for oxygen increases as more oxygen molecules are associated with it when one binds, Hb changes shape meaning others bind more easily
explaining S shape of curve
How carbon dioxide affects haemoglobin
When carbon dioxide dissolves in liquid, carbonic acid forms decreases pH causing Hb to change shape
affinity decreases at respiring tissues
more oxygen is unloaded
Bohr effect
High carbon dioxide partial pressure
causes oxyhaemoglobin curve to shift to the right