Topic 2 Cell Physiology Flashcards
What are some types of extracellular molecules that receptor proteins can bind?
Hormones, neurotransmitters
Ligand
Molecules that bind to a receiving proteins
Describe the steps of glucose uptake in terms of receptor proteins
1- insulin binds to receptor on skel.muscle or adipose tissue
2- triggers movement of more glucose transporters to cell membrane
3-increase in glucose movement from blood into cells
Membrane proteins: enzymes
Control chemical reactions on outer or inner surface
What are 2 enzymes
1-acetylcholinesterase- breaks down Ach
2-Na+/K+-ATPase
Membrane proteins: Linker proteins
Anchor cell membrane to cytoskeleton or an adjacent cell
What do junctional proteins between cells form?
Desmosomes, tight junctions, gap junctions
How do linker proteins anchor in the ECF?
Through extra cellular fibres that are usually glycoproteins
Membrane proteins: identifying proteins
Example: Major Histocompatibility Complex proteins identify cell as part of the body and foreign. They’re present in all cells except rbcs
Membrane carbohydrates function
Allow cells to recognize type- sperm recognizes egg
Membrane carbohydrates are
Glycoproteins and glycolipids
Transport proteins includes
Channels and carrier proteins
Channels
Selectively permit channel-mediated facilitated diffusion of specific ions
Gated channels open and close how?
In response to stimuli
Non-gated channels are also called what?
Leakage channels
Carrier protein function
Bind solute and carry it across membrane
What type of transport happens with carrier proteins
Active transport and facilitated transport
What’s an example of a carrier protein
Glucose transporters
Phospholipid bilayer
Continuous layer across membrane that is a barrier to water soluble molecules and not to small or lipid soluble molecules
Membrane transport is?
The movement of material between the intra and extracellular fluid
Solute
Substance dissolved in a solution
Solvent
Substance solute is dissolved in-> water
What are the types of transport
Passive transport and Active transport
Does passive transport require energy?
No it doesn’t require ATP
Passive transport moves down its concentration gradient, in other terms?
It moves from high to low concentration
What are the types of Passive transport
Simple diffusion, facilitated diffusion, facilitated transport and Osmosis