Topic 15 Flashcards
Dialysis=
filtering metabolic waste products from blood
–separation of dissolved substances from a solution by allowing the solution to diffuse through a semipermeable membrane
Hemodialysis=
Removing waste products such as creatinine and urea, as well as free water from the blood when the kidneys are in renal failure
Peritoneal Dialysis (PD) =
A treatment for patients with severe chronic kidney disease. The process uses the patient’s peritoneum as a membrane across which fluids and dissolved substances (electrolytes, urea, glucose, albumin and other small molecules) are exchanged
Continuous Ambulatory Peritoneal Dialysis (CAPD)=
Fluid is introduced through a tube in the abdomen and flushed out either every night while the patient sleeps or via regular exchanges throughout the day
PD is used as an alternative to what?
hemodialysis (especially in kidlets)
what is in the Dialysate Solution
Contains chemicals in concentrations similar to blood, a
mixture of purified water and measured chemicals, which flows counter current on the outside
Substances that must remain in the bloodstream, such as (4), are in the dialysate in concentrations similar to blood
glucose, sodium, calcium, and magnesium
The composition of the dialysate determines what?
which solutes pass out of and which stay in the blood during dialysis.
Dialyzer=
an artificial kidney filter designed to provide controllable transfer of solutes and water across a semi permeable membrane separating flowing blood and dialysate streams
The transfer processes for dialysis and ultrafiltration are by what means?
diffusion (dialysis) and convection (ultrafiltration).
what are three basic dialyzer designs?
coil
parallel plate
hollow fiber configurations
Convection=
transport of a constituent by bulk motion of fluid.
–one of the major modes of mass transfer.
Diffusion=
transport due to gradients in concentrations
–another major mode of transfer (Diffusive transport)
REVIEW BLOOD CHEMISTRY VALUES
now :)
Acute renal failure (ARF)=
a sudden loss of kidney function (hypovolemia).
- -Causes include low blood volume
- -Exposure to harmful substances
- -May be obstruction of the urinary tract
- -what we can cause on CPB
Chronic kidney disease (CKD)=
A long a slow process of kidneys losing their function
–is identified by significantly elevated creatinine
End-Stage renal disease (ESRD)=
when kidneys have completely shut down
Renal failure is described as what?
a decrease in glomerular filtration rate (GFR)
how is renal failure is typically detected?
by an elevated serum creatinine level
what 3 things are used to Diagnose on the basis of lab findings for Acute Renal Failure?
- elevated blood urea nitrogen (BUN)
- Elevated creatinine
- inability of the kidneys to produce sufficient amounts of urine.
name 5 Complications of ARF
metabolic acidosis, high potassium levels, uremia changes in body fluid balance effects to other organ systems.