Topic 1: Introduction to Physiology Flashcards
Physiology
Study of how the body functions
Homeostasis
ability to maintain relatively stable conditions in the internal environment, despite changes in external environment
Body and cell survival
conditions must be maintained within physiological limits
Conditions controlled include
- pH
- temperature
- blood gases (CO2, O2)
- blood pressure (b.p.)
- intracellular + extracellular (ICF + ECF) fluid volumes
organ systems
function together to maintain homeostasis
Disease
failure to maintain homeostasis
Nervous and/or endocrine system(s) control all other systems
Act to:
- maintain homeostasis
- permit departures from homeostasis in a controlled manner e.g. pregnancy, growth, sudden fright
Homeostasis Regulation
- Change in internal environment must be detected or anticipated
- NS and/or endocrine respond altering system(s) responsible for that condition
Types of NS/Endocrine Responses
- Anticipatory Responses
- Feedback Mechanisms
Anticipatory Responses
- e.g. ⇑ respiratory rate at start of exercise ⇒ proprioceptors (NS sensory receptors) signal movement before a change in internal conditions (gases in blood)
- may also be learned or behavioral
Feedback Mechanisms
- mechanisms that respond to change in system
- consist of set points, receptors, control areas, and effectors
- variable is monitored by receptors ⇒ info (input) fed back to control area (NS/endocrine gland) ⇒ controls the effector (output)
Set point
range of values of a variable (e.g. body temp.) that do not bring about a response (i.e. “normal range”)
Types of Feedback Mechanisms
- Negative Feedback
- Positive Feedback
Negative Feedback
- Most common homeostatic control mechanism
- Result of “output” - variable moves back toward the set point i.e. in opposite (negative) direction to the change that triggered the response (“input”)
Positive Feedback
- Less common - NOT homeostatic
- Output intensifies the input
- Continues until end point