Topic 1 - DNA & Genetic code Flashcards
What is Deoxyribose nucleic acid (DNA)?
long chain of nucleotides in the nucleus
What does every DNA nucleotide consist of?
- Phosphate
- Deoxyribose sugar
- Base
What are the 4 types of bases in DNA?
Adenine - Thymine
Guanine - Cytosine
What are the 4 types of bases in RNA?
Adenine - Uracil
Guanine - Cytosine
What structure is DNA?
Double helix
What did Chargaff discover?
Base equivalence
What did Franklin & Wilkins discover?
The helical structure of DNA
What did Watson & Crick discover?
The double helix structure
What are amino acids?
The building blocks of polypeptides & proteins
What is a polypeptide?
A sequence of amino acids linked by peptide bonds
What are proteins?
Molecules formed of 1 or more polypeptide chains
permanent changes made to DNA are?
mutations
What is base substitution?
when one base replaces another
What is base insertion? and base deletion?
insertion sees one added and deletion sees one be removed
Differences in RNA
- RNA is single stranded
- Has the base Uracil over Thymine
- Has ribose sugar instead of deoxyribose
What are the steps of semi-conservative replication?
- DNA helicase unzips DNA, breaking the hydrogen bonds.
- The original strands are templates, allowing for complementary base pairing.
- They are joined together by DNA polymerase.