Topic 1-6 Paper 1 Flashcards
What are the three principles of cell theory?
- All living organisms are composed of one or more cells
- The cell is the smallest unit of life
- All cells arise from pre-existing cells
What evidence supports cell theory?
Microscopic observations: all living things contain cells
Pasteur’s experiment: Showed that new cells do no spontaneously arise
Cell division: cells come from pre-existing cells
What are the exception to the cell theory?
Striated muscle cells: Multi-nucleated and very large
Aseptate fungal hyphae: Continuous cytoplasm with multiple nuclei
Giant Algae (Acetabularia): Can be up to 10cm long but contain only one nucleus
What are the seven functions of life?
MR H GREN
Metabolism: Chemical reactions inside the cell (ex. Respiration)
Reproduction: Producing offspring (asexual or sexual)
Homeostasis: Maintaining internal balance (ex. Temperature)
Growth: Increase in side or number of cells
Response: Reacting to stimuli in the environment
Excretion: Removal of metabolic waste (ex. CO2)
Nutrition: Obtaining fod for energy and materials
How does surface area to volume ration affect cell size?
Smaller cells have a larger SA:V ratio, allowing efficient diffusion of nutrients and waste removal.
Larger cells have a smaller SA:V ratio, making diffusion inefficient, leading to division or adaptations (e.g., folding membranes).
What are emergent properties?
Properties that arise from the interaction of individual components in a system (e.g., tissues forming an organ).
What are the differences between prokaryotic and eukaryotic cells?
Nucleus: No nucleus (nucleoid) [prokaryotic] ,True nucleus with nuclear membrane [eukaryotic]
DNA Structure: Circular, naked DNA [prokaryotic], Linear DNA with histones [eukaryotic]
Organelles: No membrane-bound organelles [prokaryotic],Has organelles (e.g., mitochondria, ER) [eukaryotic]
Ribosomes: 70S ribosomes [prokaryotic],80S ribosomes [eukaryotic]
Size: Smaller (1-5 μm) [prokaryotic],Larger (10-100 μm) [eukaryotic]
What are the functions of organelles in eukaryotic cells?
Nucleus: Contains genetic material, controls cell activities.
Rough ER: Synthesizes and transports proteins.
Smooth ER: Synthesizes lipids, detoxifies substances.
Golgi apparatus: Modifies, packages, and sorts proteins for secretion.
Lysosomes: Contains hydrolytic enzymes for digestion (only in animal cells).
Mitochondria: Site of ATP production via aerobic respiration.
Chloroplasts: Site of photosynthesis (plants only).
Ribosomes: Synthesizes proteins (80S in eukaryotes, 70S in prokaryotes).
Vacuole: Storage of water, nutrients, and waste.
What is the fluid mosaic model of the membrane?
Describes the phospholipid bilayer with embedded proteins that allow flexibility.
Fluid: Phospholipids move laterally.
Mosaic: Proteins are scattered throughout the bilayer.
What is the role of cholesterol in animal cell membranes?
Reduces membrane fluidity at high temperatures.
Prevents solidification at low temperatures.
Helps maintain membrane structure.
What are the functions of membrane proteins?
Mnemonic: TRACIE
Transport: Channels and pumps for substances.
Receptors: Detect hormones and neurotransmitters.
Adhesion: Cell-to-cell attachment.
Cell recognition: Glycoproteins act as ID tags.
Intercellular joining: Tight junctions in tissues.
Enzymes: Catalyze reactions at the membrane.
What are the types of passive transport?
Simple diffusion: Movement of small, non-polar molecules (e.g., O₂, CO₂) across the membrane.
Facilitated diffusion: Uses channel/carrier proteins for large or charged molecules (e.g., glucose, Na⁺).
Osmosis: Diffusion of water through a selectively permeable membrane.
What is active transport?
Movement of substances against the concentration gradient using ATP (e.g., sodium-potassium pump).
What is the difference between endocytosis and exocytosis?
Endocytosis: Cell engulfs material via vesicles (e.g., phagocytosis for solids, pinocytosis for liquids).
Exocytosis: Vesicles fuse with the membrane to release contents (e.g., neurotransmitter secretion).
What did Pasteur’s experiment demonstrate?
Disproved spontaneous generation by showing that broth only spoiled when exposed to microbes.
What is the endosymbiotic theory?
Explains how mitochondria and chloroplasts evolved from prokaryotic cells being engulfed by larger cells.
Evidence:
- Mitochondria & chloroplasts have their own DNA.
- Double membranes suggest engulfment.
- 70S ribosomes (like prokaryotes).
What are the stages of the cell cycle?
Interphase (G1, S, G2): Growth and DNA replication.
Mitosis: Division of nucleus.
Cytokinesis: Division of cytoplasm.
What happens in each miotic phase?
Prophase: Chromosomes condense, nuclear membrane dissolves
Metaphase: Chromosomes line up at equator
Anaphase: Sister chromatids separate and move to poles
Telophase: Nuclear membrane reforms, cytokinesis begins
How is the cell cycle controlled?
Cyclins: Proteins that regulate the cycle.
Checkpoints: Ensure DNA is properly replicated before division.
What is cancer and how does it occur?
Uncontrolled cell division due to mutations in oncogenes or tumor suppressor genes.
Metastasis: Cancer cells spread to other tissues.
What are the four macromolecules essential for life?
Carbohydrates – Energy storage and structural support.
Lipids – Long-term energy storage, insulation, and membranes.
Proteins – Enzymes, transport, structural functions.
Nucleic Acids – Store and transmit genetic information (DNA, RNA).
What is metabolism?
The sum of all enzyme-controlled reactions in an organism, including anabolism and catabolism.
What is the difference between anabolism and catabolism?
Anabolism: Builds larger molecules from smaller ones using condensation reactions (e.g., protein synthesis).
Catabolism: Breaks down larger molecules into smaller ones using hydrolysis reactions (e.g., digestion).
What are the properties of water and their biological importance?
Cohesion: Water molecules stick to each other. It deals with surface tension (ex., insects walking on water)
Adhesion: Water sticks to other surfaces. It deals with water transport in the xylem of plants.
High specific heat: Water resists temperature changes. Stable environment for aquatic life.
Solvent: Dissolves polar substances—transports nutrients and waste in blood.
High latent heat of vaporization: Water absorbs heat before evaporating. Cooling effect via sweating.