Tophat Mideterm 1 Flashcards

1
Q

Raymond Pearl was the first biologist who was in favor of eugenics who utilized statistical methods to solve biological problems such as substance usage and life expectancy
A) True
B) False

A

False

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2
Q

The four forces of evolution include: natural selection, genetic drift, gene flow, and mutations
A) True
B) False

A

True

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3
Q

What type of genetic mutation causes sickle cell anemia?
A) Deletion
B) Insertion
C) Point
D) Transcription
E) None of the above

A

Point (aka substitution)

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4
Q

When the observed genotype frequency of a population is the same as the expected genotype frequency, the population is evolving
A) True
B) False

A

False, in HWE not evolving

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5
Q

Paul T. Baker contributed to Human Population Biology by advancing and broadening the understanding of human adaptability
A) True
B) False

A

True

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6
Q

Globalization has only impacted human biology and genetics through the spread of infectious disease
A) True
B) False

A

False, other ways not just disease

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7
Q

Non-disjunction only occurs during meiosis 1
A) True
B) False

A

False, also occurs meiosis 1 and 2 and in mitosis (Trisomy 21,13,18)

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8
Q

Translocation always leads to intellectual and/or physical disabilities
A) True
B) False

A

False, doesn’t always lead to it

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9
Q

Which of the following is not required for Hardy-Weinberg Equilibrium?
A) No gene flow
B) No new mutations
C) No sexual selection
D) Random mating
E) Small population

A

Small population, needs a large population for HWE all other options cause new genes in pool, small populations causes genetic drift (founders and bottleneck)

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10
Q

The unit of natural selection is population
A) True
B) False

A

False, the unit is the individual, population is the unit of evolution

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11
Q

Someone born with the sex chromosome OY will be a male
A) True
B) False

A

False, it would not become anything because you need an X which is the default setting (women/Turners syndrome)

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12
Q

If the degree to which monozygotic twins show the same phenotype is low, the trait is likely not genetic. This is called
A) equal concordance
B) low concordance
C) low plasticity
D) high plasticity
E) penetrants

A

Low concordance, gene or allele is directly bonding to the phenotype, not discrete trait is a continuous/polygenic trait, environment doing influencing on trait, penetrance is example of prostate cancer

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13
Q

A genotype is the genetic makeup of an individual
A) True
B) False

A

False, the GENOME is the genetic makeup of an individual, genotype just alleles for specific trait

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14
Q

Red-green color blindness is a X-linked recessive trait
A) True
B) False

A

True, carried on X chromosome, need both x’s to express it for females and one the one x for males to be expressed, hemezygote

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15
Q

The original mRNA strand is: AUG GGG GCU UCA CUC ACU GAG CAG. A mutation occurs and the new mRNA strand is: AUG GGG GCU UgA CUC ACU GAG CAG. What type of mutation is this?
A) Frameshift
B) Missense
C) Nonsense
D) Quiet
E) Silent

A

Nonsense, because the UGA becomes a stop codon, not Frameshift cause nothing shifting, not quiet cause not a type of mutation, if not a stop codon and still same amino acid then silent mutation, Missense is code for different amino acid

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16
Q

Natural selection decreases variation in traits within a population
A) True
B) False

A

True, on chart that has arrows

17
Q

Which of the following is not a sex-linked trait?
A) Albinism
B) Hairy ear rims
C) Hemophilia
D) Red-green color blindness
E) Tay-Sachs

A

Tay-Sachs