Tophat Mideterm 1 Flashcards
Raymond Pearl was the first biologist who was in favor of eugenics who utilized statistical methods to solve biological problems such as substance usage and life expectancy
A) True
B) False
False
The four forces of evolution include: natural selection, genetic drift, gene flow, and mutations
A) True
B) False
True
What type of genetic mutation causes sickle cell anemia?
A) Deletion
B) Insertion
C) Point
D) Transcription
E) None of the above
Point (aka substitution)
When the observed genotype frequency of a population is the same as the expected genotype frequency, the population is evolving
A) True
B) False
False, in HWE not evolving
Paul T. Baker contributed to Human Population Biology by advancing and broadening the understanding of human adaptability
A) True
B) False
True
Globalization has only impacted human biology and genetics through the spread of infectious disease
A) True
B) False
False, other ways not just disease
Non-disjunction only occurs during meiosis 1
A) True
B) False
False, also occurs meiosis 1 and 2 and in mitosis (Trisomy 21,13,18)
Translocation always leads to intellectual and/or physical disabilities
A) True
B) False
False, doesn’t always lead to it
Which of the following is not required for Hardy-Weinberg Equilibrium?
A) No gene flow
B) No new mutations
C) No sexual selection
D) Random mating
E) Small population
Small population, needs a large population for HWE all other options cause new genes in pool, small populations causes genetic drift (founders and bottleneck)
The unit of natural selection is population
A) True
B) False
False, the unit is the individual, population is the unit of evolution
Someone born with the sex chromosome OY will be a male
A) True
B) False
False, it would not become anything because you need an X which is the default setting (women/Turners syndrome)
If the degree to which monozygotic twins show the same phenotype is low, the trait is likely not genetic. This is called
A) equal concordance
B) low concordance
C) low plasticity
D) high plasticity
E) penetrants
Low concordance, gene or allele is directly bonding to the phenotype, not discrete trait is a continuous/polygenic trait, environment doing influencing on trait, penetrance is example of prostate cancer
A genotype is the genetic makeup of an individual
A) True
B) False
False, the GENOME is the genetic makeup of an individual, genotype just alleles for specific trait
Red-green color blindness is a X-linked recessive trait
A) True
B) False
True, carried on X chromosome, need both x’s to express it for females and one the one x for males to be expressed, hemezygote
The original mRNA strand is: AUG GGG GCU UCA CUC ACU GAG CAG. A mutation occurs and the new mRNA strand is: AUG GGG GCU UgA CUC ACU GAG CAG. What type of mutation is this?
A) Frameshift
B) Missense
C) Nonsense
D) Quiet
E) Silent
Nonsense, because the UGA becomes a stop codon, not Frameshift cause nothing shifting, not quiet cause not a type of mutation, if not a stop codon and still same amino acid then silent mutation, Missense is code for different amino acid