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Cardio2 > Top 300 Workshop > Flashcards

Top 300 Workshop Flashcards

1
Q

Labetalol

MOA

A

Adrenergic receptor blocking agent that possesses blocking activities for both nonselective, competitive beta-adrenergic receptors and selective, competitive a1 adrenergic receptors in a single substance

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2
Q

Labetalol SE

A

Orthostatic Hypotension
Nasal Congestion
Bronchospasm
Hyperkalemia

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3
Q

Labetalol Class and IND

A

Beta Blocker

HTN & HTN Crisis

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4
Q

Verapamil class and ind

A

CCB
AFib/flutter
HTN
Angina

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5
Q

Verapamil MOA

A

L-type calcium channel inhibitor (slow-channel blocker) that selectively blocks the transmembrane influx of calcium ions into arterial smooth muscles including conductible and contractile myocardial cells, without affecting the concentration of serum calcium.

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6
Q

Verapamil SE

A

Edema
HypOtension
Constipation
HA

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7
Q

Triamterene/HCTZ

C&I

A

Tri-Pot Sparing diuretic
HCTZ-Thiazide diuretic

Edema and Hypertension

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8
Q

Triamterene/HCTZ MOA

A

Triamterene, a potassium-sparing diuretic, inhibits the reabsorption of sodium in exchange for potassium and hydrogen ions by exerting a direct effect on the distal renal tubule.
Hydrochlorothiazide is an antihypertensive and diuretic agent that affects the electrolyte reabsorption at the distal renal tubule resulting in increased excretion of sodium and chloride in equal amounts. The antihypertensive action of thiazides is still unknown

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9
Q

Tri/HCTZ SE

A 
Hyperkalemia
hyperuricemia
Hypotension,
electrolyte abnormalties
hyperglycemia
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10
Q

Tri/HCTZ BBW

A

May cause hyperkalemia which if uncorrected can be fatal

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11
Q

Valsartan Class and Ind

A

ARB

HTN

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12
Q

Valsartan MOA

A

nonpeptide angiotensin II receptor antagonist (ARB), selective for the AT1 receptor

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13
Q

Valsartan SE

A

Hypotension
Increase BUN, SCr
Angioedema

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14
Q

BBW Valsartan

A

PREGGO

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15
Q

Quinapril Class and Ind

A

ACE-I

HTN

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16
Q

Quinapril MOA

A

Quinapril hydrochloride is rapidly converted to quinaprilat, an angiotensin converting enzyme (ACE) inhibitor, that prevents the conversion of angiotensin I to angiotensin II which is a potent vasoconstrictor agent

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17
Q

Quinapril SE

A

Hyperkalemia
angioedema
cough

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18
Q

Quinapril BBW

A

PREGGO

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19
Q

Ramipril Class and IND

A

ACE-I

HTN

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20
Q

Ramipril MOA

A

an angiotensin-converting enzyme (ACE) inhibitor, is metabolized to a more potent ramiprilat (active drug)

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21
Q

Ramipril SE

A

Hyperkalemia
angioedema
cough

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22
Q

Ramipril BBW

A

PREGGO

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23
Q

Lisinopril class IND

A

ACE-I

HTN

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24
Q

Lisinopril MOA

A

Lisinopril is a long-acting ACE inhibitor. ACE inhibition prevents the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor

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25
Q

Lisinopril SE

A

Hyperkalemia
Angioedema
cough

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26
Q

Lisinopril BBW

A

PREGGO

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27
Q

Losartan class IND

A

ARB

HTN

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28
Q

Losartan MOA

A

nonpeptide angiotensin II receptor antagonist (ARB), selective for the AT1 receptor

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29
Q

Losartan SE

A

Hypotension
Increased BUN, SCr
Angioedema

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30
Q

Losartan BBW

A

PREGGO

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31
Q

Chlorthalidone Class IND

A

Thiazide Diuretic
Edema
HTN

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32
Q

Chlorthalidone MOA

A

Chlorthalidone is a long-acting, oral monosulfanyl diuretic with antihypertensive activity, acting on the distal convoluted tubule of the nephron. Sodium and water depletion appear to provide a basis for its antihypertensive effect

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33
Q

Chlorthalidone SE

A

Hyperuricemia
Toxic epidermal necrolysis
jaundice

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34
Q

Clonidine class IND

A

Alpha 2 agonist
HTN crisis
ADHD

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35
Q

Clonidine MOA

A

stimulates alpha 2-adrenergic receptors in the brain resulting in reduced sympathetic outflow from the CNS and decreased peripheral resistance, renal vascular resistance, heart rate, and blood pressure

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36
Q

Clonidine SE

A 
Xerostomia
HA
Somnolence,
Pruritis
Fatigue
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37
Q

Clonidine BBW

A

Hemodynamic instability
Hypotension
Bradycardia

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38
Q

Enalapril Class IND

A

ACE-I

HTN

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39
Q

Enalapril MOA

A

Enalapril maleate inhibits angiotensin-converting enzyme (ACE) after hydrolysis to enalaprilat.

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40
Q

Enalapril SE

A

Hyperkalemia
angioedema
cough

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41
Q

Enalapril BBW

A

PREGGO

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42
Q

Amlodipine Class IND

A

Dihydro-CCB
Stable Angina
Variant Angina
HTN

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43
Q

Amlodipine MOA

A

Amlodipine is a dihydropyridine calcium channel blocker that exerts its effect by blocking the transmembrane influx of calcium ions into cardiac and vascular smooth muscles

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44
Q

Amlodipine SE

A 
Edema
Abdominal pain
nausea
fatigue
Somnolence
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45
Q

Benazepril class IND

A

ACE-I

HTN

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46
Q

Benazepril MOA

A

Benazepril hydrochloride (prodrug) is hepatically cleaved to form its active drug benazeprilat, which is a more potent non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor.

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47
Q

Benazepril SE

A

Hyperkalemia
Angioedema
cough

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48
Q

Benazepril BBW

A

PREGGO

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49
Q

HCTZ Class IND

A

Thiazide

Edema HTN

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50
Q

HCTZ MOA

A

antihypertensive and diuretic agent that affects the electrolyte reabsorption at the distal renal tubule resulting in increased excretion of sodium and chloride in equal amounts. The antihypertensive action of thiazides is still unknown.

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51
Q

HCTZ SE

A

Hypotension

hyperglycemia

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52
Q

Olmesartan Class IND

A

ARB

HTN

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53
Q

Olmesartan MOA

A

Olmesartan blocks the vasoconstrictor effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in vascular smooth muscle.

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54
Q

Olmesartan SE

A

Hypotension

Renal Issues

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55
Q

Olmesartan BBW

A

PREGGO

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56
Q

Hydralazine Class IND

A

Vasodilators
Essential HTN
CHF
Preggo induced HTN

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57
Q

Hydralazine MOA

A

exhibiting a peripheral-vasodilating effect through a direct relaxation of vascular smooth muscle

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58
Q

Hydralazine SE

A 
Ha
tachycardia
NVD
edema
Angina pectoris
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59
Q

Atorvastatin Class IND

A

Statins

Hyperlipidemia

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60
Q

Atorvastatin MOA

A

selectively and competitively inhibits HMG-CoA reductase, a rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a sterol and cholesterol precursor

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61
Q

Atorvastatin SE

A

Diarrhea
Rhabdomyolysis
Arthralgia

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62
Q

STATINS ARE CI IN

A

Preggo

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63
Q

Ezetimibe class IND

A

Cholesterol absorption inhibitor
Hyperlipidemia
Familial hypercholesterolemia

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64
Q

Ezetimibe MOA

A

Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine to inhibit the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. This reduces hepatic cholesterol stores and increases the clearance of cholesterol from the blood

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65
Q

Fenofibrate class and IND

A

Fibrate

Hyperlipidemia

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66
Q

Fenofibrate MOA

A

activation of peroxisome proliferator activated receptor alpha (PPARalpha).

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67
Q

Fenofibrate SE

A 
LFT abnormalties
abdominal pain
nausea
backache
rhabdomyolysis
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68
Q

Gemfibrozil class and ind

A

Fibrate

Hyperlipidemia

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69
Q

Gemfibrozil MOA

A

exhibits its lipid-lowering effect mostly via stimulation of peroxisome proliferator activated receptor alpha, which causes a decrease in triglyceride levels and an increase in high-density lipoprotein levels, with a modest decrease in low-density lipoprotein

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70
Q

Gemfibrozil SE

A

Abdominal pain
increase LFTs
drug-induced myopathy
rhabdomyolysis

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71
Q

Lovastatin Class and INd

A

Statin

Hyperlipidemia

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72
Q

Lovastatin MOA

A

It prevents the conversion of HMG-CoA to mevalonate which is rate limiting step in the biosynthesis of cholesterol.

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73
Q

Lovastatin SE

A

Diarrhea
rhabdomyolysis
arthralgia

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74
Q

Pravastatin Class IND

A

Statin

Hyperlipidemia

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75
Q

Pravastatin MOA

A

It prevents the conversion of HMG-CoA to mevalonate which is rate limiting step in the biosynthesis of cholesterol.

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76
Q

Pravastatin SE

A

Diarrhea
rhabdomyolysis
arthralgia

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77
Q

Omega-3-acid Ethyl Esters MOA

A

The mechanism of action is not entirely understood, however, possible mechanisms of action include the inhibition of acyl coenzyme A:1,2-diacylglycerol acyltransferase and increased peroxisomal beta-oxidation in the liver

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78
Q

Omega SE

A

Burping
Indegestion
Taste sense altered

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79
Q

Omega 3 Indication

A

Hypertriglyceridemia

80
Q

Clopidogrel IND

A

Acute STEMI
Unstable angina
NSTEMI

81
Q

Clopidogrel MOA

A

that inhibits platelet aggregation by selectively and irreversibly binding to the adenosine diphosphate (ADP) P2Y12 receptor on platelets

82
Q

Clopidogrel SE

A

Bleeding

83
Q

Clopidogrel BBW

A

Consider use of another platelet P2Y12 inhibitor in patients identified as CYP2C19 poor metabolizers

84
Q

Dabigatran class IND

A

Direct thrombin inhibitor
VTE (treatment and prevention)
Nonvalvular AFib
Post-op thromboprophylaxis

85
Q

Dabigatran SE

A

Dyspepsia

bleeding

86
Q

Dabigatran BBW

A

Thrombotic events

Premature D/C increases risk for thrombotic events

87
Q

Enoxaparin class and IND

A

LMWH
Prophylaxis of VTE
VTE/Unstable angina/NTEMI/ STEMI

Off-label: VTE in pregnancy

88
Q

Enoxaparin MOA

A

Enoxaparin sodium is a low molecular weight heparin which has anti-factor Xa and anti-thrombin (anti-factor IIa) activities that confer antithrombotic properties

89
Q

Enoxaparin SE

A

Bleeding, anemia, thrombocytopenia, increased LFTs, injection site rxn

90
Q

Enoxaparin BBW

A

patients who have spinal or epidural anesthesia or spinal puncture carries an increased risk of bleeding and bruising. This bleeding and bruising may lead to long-term or permanent paralysis

91
Q

Prasugrel class and IND

A

P2Y12 Inhibitor

Percutaneous coronary intervention for ACS

92
Q

Prasugrel MOA

A

Prasugrel is a thienopyridine which inhibits platelet activation and aggregation via irreversible inhibition of the platelet P2Y12 adenosine diphosphate (ADP) receptor

93
Q

Prasugrel SE

A

Bleeding, hypertension, hyperlipidemia, AFib, bradyarrhythmia, neoplasm of colon

94
Q

Prasugrel BBW

A

Prasugrel can cause significant and sometimes fatal bleeding. Do not use prasugrel in patients with active pathological bleeding or a history of transient ischemic attack or stroke.***

95
Q

Rivaroxaban class and IND

A

Direct Xa inhibitor

DVT/PE treatment
Nonvalvular AFib

96
Q

Rivaroxaban MOA

A

Rivaroxaban selectively inhibits factor Xa without the need of a cofactor (eg, anti-thrombin III) for activity

97
Q

Rivaroxaban SE

A

Bleeding, syncope, drug withdrawal (Stroke, non-CNS embolism)

98
Q

Rivaroxaban BBW

A

Premature discontinuation of any oral anticoagulant, including rivaroxaban, increases the risk of thrombotic events.

99
Q

Warfarin class IND

A

Vit K anticoag
Thromboembolic complications (Prophylaxis and Tx)
MI

100
Q

Isosorbide class IND

A

Vascular dilator

Stable angina: Prophylaxis

101
Q

Isosorbide MOA

A

It exerts its effect by relaxing vascular smooth muscles resulting in dilatation of peripheral arteries and veins, especially the veins.

102
Q

Isosorbide SE

A 
Hypotension
Edema
HF
MI
AFib
103
Q

Nebivolol class and IND

A

Beta Blocker

HTN Off-Label CHF

104
Q

Nebivolol MOA

A

Nebivolol is a long-acting cardioselective beta-1 adrenoceptor antagonist without membrane stabilizing or intrinsic sympathomimetic activities

105
Q

Nebivolol SE

A

NV
HA
Somnolence

106
Q

Nitroglycerin class IND

A

Organic Nitrate Vasodilating Agent

Prevention of MI and acute MI

107
Q

Nitroglycerin MOA

A

Nitroglycerin, an organic nitrate, is a vasodilating agent that relieves tension on vascular smooth muscle and dilates peripheral veins and arteries. It increases guanosine 3’5’ monophosphate (cyclic GMP) in smooth muscle and other tissues by stimulating guanylate cyclase through formation of free radical nitric oxide.

108
Q

Nitroglycerin SE

A

Hypotension
Flushing
HA

109
Q

Propranolol class IND

A

BetaBlocker

HTN
Essential Tremors
Migraines

110
Q

Propranolol MOA

A

Propranolol hydrochloride is a nonselective beta-blocker that reduces chronotropic, inotropic and vasodilator responses to beta-adrenergic stimulation by competing for available binding sites that stimulate the beta-adrenergic receptors.

111
Q

Propranolol SE

A

D/V, hypoglycemia, bronchospasms, withdrawal symptoms

112
Q

Propranolol BBW

A

Dont stop abruptly, exacerbations of angina pectoris and MI have occured.

113
Q

Digoxin Class IND

A

Cardiac glycosides

AFib HF

114
Q

Digoxin MOA

A

Digoxin inhibits sodium-potassium ATPase, which increases intracellular sodium concentration leading to increased intracellular calcium concentration.

115
Q

Digoxin SE

A

NV
HA
Mental Disorders
Thrombocytopenia

116
Q

Diltiazem class IND

A

CCB

Atrial arrhythmia
HTN
PSV tachycardia
Stable Angina

117
Q

Diltiazem MOA

A

Diltiazem hydrochloride is a slow calcium channel blocker that blocks calcium ion influx during depolarization of cardiac and vascular smooth muscle.

118
Q

Diltiazem SE

A

Peripheral edema
Bradyarrhythmia
HA

119
Q

Amiodarone class IND

A

Antiarrhythmic

Ventricular Arrhythmia (Tx and prophylaxis)

120
Q

Amiodarone MOA

A

Amiodarone HCl is an antiarrhythmic drug with predominant class III effects of lengthening cardiac action potential and blocking myocardial potassium channels leading to slowed conduction and prolonged refractoriness

121
Q

Amiodarone SE

A

Hypotension, photosensitivity, visual disturbance, pulmonary toxicity, blue/grey skin

122
Q

Amiodarone BBW

A

serious lung problems, liver problems, worsening of your irregular heart rate, and loss of vision

** its all of the monitoring parameters

123
Q

Atenolol Class and IND

A

Beta blocker

HTN
Acute MI
Angina Pectoris

124
Q

Atenolol MOA

A

Atenolol is a synthetic beta(1)-selective adrenoreceptor blocking agent without membrane stabilizing or intrinsic sympathomimetic activities.

125
Q

Atenolol SE

A

Bradyarrhythmia, hypotension, fatigue, depression, withdrawal symptoms

126
Q

Bisoprolol class IND

A

Beta Blocker

HTN Angina pectoris CHF AFib

127
Q

Bisoprolol MOA

A

cardioselective inhibitor of beta(1)-adrenoceptor, has no significant intrinsic sympathomimetic activity or membrane stabilizing activity in its therapeutic dosage. It also exhibits beta(2)-adrenoceptor inhibition and a negative chronotropic effect

128
Q

Bisoprolol SE

A

D/HA

fatigue

129
Q

Carvedilol class IND

A

Beta Blocker

HTN HF
Impaired left ventricular function
MI

130
Q

Carvedilol MOA

A

nonselective beta-adrenergic blocking agent with alpha 1-adrenergic blocking activity and no intrinsic sympathomimetic activity

131
Q

Carvedilol SE

A

Bradyarrhythmia, hypotension, peripheral edema, fatigue, ED

132
Q

Furosemide Class IND

A

Loop Diuretic

CHF-edema
HTN
Pulmonary edema
Ascites

133
Q

Furosemide MOA

A

potent diuretic that works by blocking the absorption of sodium and chloride in the kidney tubules (proximal and distal tubules, also in the loop of Henle), causing a profound increase in urine output

134
Q

Furosemide SE

A

Electrolyte abnormalities, orthostatic hypotension, hyperuricemia

135
Q

Furosemide BBW

A

if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion

136
Q

Metoprolol Succinate or Tartrate Class IND

A

Beta Blocker

HTN
Angina Pectoris
CHF

137
Q

Metoprolol MOA

A

beta-adrenergic blocker with selective activity on beta-1 adrenoreceptors located mainly in cardiac muscles

138
Q

Metoprolol SE

A

Bradyarrhythmia, hypotension, depression, fatigue, withdrawal symptoms

139
Q

Spirinolactone Class IND

A 
Aldosterone receptor Antagonist
Cirrhosis of liver- edema
Edema
Hyperaldosteronism
HTN-add on
HF
140
Q

SpirinolactoneMOA

A

inhibits the effect of aldosterone by competing for the aldosterone-dependent sodium-potassium exchange site in the distal tubule cells. This increases the secretion of water and sodium, while decreasing the excretion of potassium

141
Q

Spirinolactone SE

A

Gynecomastia, N/V/D, disorders of menstruation, ED, hyperkalemia

142
Q

Valsartan/sacubitril IND

A

HTN

143
Q

Valsartan/sacubitril MOA

A

Sacubitril is a prodrug metabolized to the active metabolite LBQ657, which inhibits neprilysin, thereby increasing levels of peptides (such as natriuretic peptides). Valsartan is an angiotensin receptor blocker that selectively blocks the AT1 receptor and inhibits angiotensin-II dependent aldosterone release

144
Q

Valsartan/sacubitril SE

A

Hypotension, hyperkalemia, angioedema, dizziness

145
Q

Valsartan/sacubitril BBW

A

PREGGO

146
Q

Apixaban class IND

A

Factor Xa inhibitor

AFib
DVT (Tx and Prophylaxis)

147
Q

Apixaban MOA

A

reversible and selective active site inhibitor of free and clot-bound FXa, resulting in decreased thrombin generation and thrombus formation.

148
Q

Apixaban SE

A

Bleeding

Hematoma

149
Q

Apixaban BBW

A

Premature discontinuation of apixaban or any oral anticoagulant increases the risk of thrombotic events

150
Q

Candesartan class IND

A

ARB

HTN

151
Q

Candesartan MOA

A

angiotensin II receptor antagonist (ARB), selective for the AT1 receptor.

152
Q

Candesartan SE

A

Hypotension, backache, dizziness

153
Q

Candesartan BBW

A

PREGGO

154
Q

Edoxaban class IND

A

Factor Xa inhibitor

AFib
DVT Prophylaxis
Pulmonary embolism

155
Q

Edoxaban MOA

A

selective inhibitor of factor Xa, reduces generation of thrombin and thrombus formation by inhibiting free factor Xa, prothrombinase activity, and thrombin-induced platelet aggregation

156
Q

Edoxaban SE

A

Rash, bleeding, anemia

157
Q

Edoxaban BBW

A

Edoxaban should not be used in patients with nonvalvular arterial fibrillation who have a CrCl greater than 95 mL/min due to an increased risk of ischemic stroke. Premature discontinuation of oral anticoagulant therapy may increase the risk of ischemic events.

158
Q

Fosinopril class IND

A

ACE-I

HTN

159
Q

Fosinopril MOA

A

an ester prodrug of a specific and competitive angiotensin-converting enzyme (ACE) inhibitor, fosinoprilat.

160
Q

Fosinopril SE

A

Hypotension, hyperkalemia, cough, angioedema

161
Q

Fosinopril BBW

A

PREGGO

162
Q

Irbesartan class IND

A

ARB

HTN

163
Q

Irbesartan MOA

A

nonpeptide angiotensin II antagonist that selectively blocks the binding of angiotensin II to the AT 1 receptor

164
Q

Irbesartan SE

A

Diarrhea, HA, angioedema

165
Q

Irbesartan BBW

A

PREGGO`

166
Q

Albuterol MOA

A

R-albuterol binds to beta-2-receptors in the bronchioles thereby leading to bronchodilation

167
Q

Albuterol SE

A

Tachycardia, Tremors, Nervousness, nausea, hypokalemia

168
Q

Albuterol IND

A

Asthma, Bronchospasm, excercise-induced asthma

169
Q

Beclomethasone MOA

A

Multifactorial that reduces production of the enzyme, phospholipase A2 causing release of arachidonic acid that can increase production of pro-inflammatory mediators

170
Q

Beclomethasone SE

A

NV, HA, sore throat, stuffy nose, cough, dryness, thrush

171
Q

Beclomethasone IND

A

Asthma

172
Q

Budesonide/formoterol MOA

A

Budesonide-glucocorticoid/mineralcorticoid activity, reduces inflammation
Formoterol- Binds to beta 2 receptors in the bronchioles to increase cAMP that cause a reduction in intracellular calcium leading to less actin and myosin interaction therebv leading to bronchodilation.

173
Q

Budesonide/formeterol SE

A

Cough, Oral pharyngeal candidiasis, HA, nausea, tremors, nervousness, decreased growth velocity

174
Q

Budesonide/formeterol IND

A

Asthma COPD

175
Q

Fluticasone MOA

A

Corticosteroid-Multifactorial that reduces production of the enzyme, phospholipase A2 causing release of arachidonic acid that can increase production of pro-inflammatory mediators

176
Q

Fluticasone SE

A

Irritation and burning to nasal passage, nosebleeds

177
Q

Fluticasone IND

A

Allergic rhinitis, nasal polyps, non-allergic rhinitis

178
Q

Fluticasone/Salmeterol MOA

A

Fluticasone-Corticosteroid ^
Salmeterol-Binds to beta 2 receptors in the bronchioles to increase cAMP that cause a reduction in intracellular calcium leading to less actin and myosin interaction thereby leading to bronchodilation.

179
Q

Fluticasone/Salmeterol SE

A

HA, pharyngitis, nausea, oral candidiasis

180
Q

Fluticasone/Salmeterol IND

A

Asthma, COPD

181
Q

Ipratroprium bromide/Albuterol MOA

A

Binds to peripheral muscarinin antagonist and to beta-2-receptors in the bronchioles to increase cAMP that cause a reduction in intracellular calcium leading to less actin and myosin interaction thereby leading to bronchodilation.

182
Q

Ipratroprium bromide/Albuterol SE

A

Tachycardia, bronchitis, cough, nausea, tremor, glaucoma

183
Q

Ipratroprium bromide/Albuterol IND

A

COPD

Off-label: ACute asthma exacerbation

184
Q

Levalbuterol MOA

A

Binds to beta 2 receptors in the bronchioles to increase cAMP that cause a reduction in intracellular calcium leading to less actin and myosin interaction therebv leading to bronchodilation.

185
Q

Mometasone MOA

A

Multifactorial that reduces production of the enzyme, phospholipase A2 causing release of arachidonic acid that can increase production of pro-inflammatory mediators

186
Q

Mometasone SE

A

Irritation and burning to nasl passage, nosebleeds

187
Q

Mometasone IND

A

Allergic rhinitis, Nasal polyps, Non-allergic rhinitis

188
Q

Montelukast MOA

A

Multifactorial that reduces production of the enzyme, phospholipase A2 causing release of arachidonic acid that can increase production of pro-inflammatory mediators

189
Q

Montelukast SE

A

Dizziness, HA, fatigue, dyspepsia

190
Q

Montelukast IND

A

Allergic rhinitis, Asthma, Exercise-induced asthma

191
Q

Tiotropium Bromide MOA

A

Binds to peripheral muscarinin antagonist and to beta-2-receptors in the bronchioles to increase cAMP that cause a reduction in intracellular calcium leading to less actin and myosin interaction thereby leading to bronchodilation.

192
Q

Tiotropium Bromide SE

A

Tachycardia, bronchitis, cough, nausea, tremor, glaucoma

193
Q

Tiotropium Bromide IND

A

Asthma COPD

194
Q

Budesonide MOA

A

Multifactorial that reduces production of the enzyme, phospholipase A2 causing release of arachidonic acid that can increase production of pro-inflammatory mediators

195
Q

Budesonide SE

A

Cough, thrush, HA, nausea

196
Q

Budesonide IND

A

Asthma, COPD, Eosinophilc esophagitis

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