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Top 300 Fall P3 > top 300 > Flashcards

top 300 Flashcards

1
Q

What is the pharmacological class of quinapril

A

ACE inhibitor

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2
Q

Which of the following is an FDA approved indication for atomoxetine

A

ADHD

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3
Q

What is an FDA approved indication for clonidine

A

ADHD

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4
Q

Which of the following is an FDA aproved indication for digoxin

A

A-fib

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5
Q

What is the major adverse reaction to hydralazine

A

agranulocytosis

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6
Q

The brand name of albendazole is

A

Albenza

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7
Q

Which is FDA indicated for the treatment of gout

A

allopurinol

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8
Q

Which of the following is the brand name of Zolpidem

A

Ambien

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9
Q

What is a major adverse reaction to ramipril

A

angioedema

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10
Q

what is a major adverse drug reaction to benazepril

A

angioedema

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11
Q

what is the pharmacological class for Atacand

A

Angiotensin Receptor Blocker

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12
Q

Which of the following is the MOA for Telmesartan

A

Antagonizes angiotensin II receptors

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13
Q

What is the pharmacological class of Ranexa

A

antianginal agent

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14
Q

What is the pharmacological class of isosorbide mononitrate

A

antianginal agent

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15
Q

the pharmacological class of benzonatate is

A

antitussive

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16
Q

the pharmacological class of acyclovir is

A

antiviral

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17
Q

which of the following is an adverse effect of modafinil

A

anxiety

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18
Q

what is a major adverse drug reaction to rifaximin

A

ascites

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19
Q

what of the following drugs is a protease inhibitor

A

Atazanavir

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20
Q

What is the brand name for irbesartan

A

Avapro

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21
Q

what is the brand name for olmesartan

A

Benicar

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22
Q

Which of the following is an FDA approved indication for doxazosin

A

BPH

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23
Q

Which of the following is an FDA approved indication for terazosin

A

BPH

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24
Q

What is the pharmacological class of metoprolol

A

Beta-blocker

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25
Q

What is the MOA for chlorhexidine

A

binds to the negatively charged cell wall and extra microbial complexes

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26
Q

What is the pharmacological class of diltiazem

A

CCB

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27
Q

What is the pharmacological class of ezetimibe

A

cholesterol absorption inhibitor

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28
Q

St John’s wort is a known inducer of CYP3A4 and Pgp; if coadministered with Xarelto, a patient might be at increased risk of treatment failure due to

A

clotting

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29
Q

St John’s wort is a known inducer of CYP3A4 and Pgp; if coadministered with dabigatran, a patient might be at increased risk of treatment failure due to

A

clotting

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30
Q

which of the following would be expected to increase the risk of bleeding in a patient stabilized on warfarin

A

co-administration of a CYP2C9 inhibitor

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31
Q

the pharmacological class of budesonide is

A

corticosteroid

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32
Q

which of the following has the potential to increase the metabolism of Sustiva thereby reducing its therapeutic effectiveness

A

A CYP3A4 inducer

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33
Q

Which of the following is an FDA approved indication for amitriptyline

A

depression

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34
Q

what is a major AE to dipyridamole

A

dizziness

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35
Q

what effect would fluoxetine have on carvedilol AUC and clearance

A

due to inhibition of CYP2D6, carvedilol clearance will decrease and the AUC will increase

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36
Q

Which of the following is the brand name of triamterene/HCTZ

A

Dyazide

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37
Q

which of the following is an approved indication for hydrochlorothiazide

A

edema

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38
Q

what is the FDA indication for phenobarbital

A

epilepsy

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39
Q

what is a major adverse drug reaction to carvedilol

A

erectile dysfunction

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40
Q

what is a major adverse drug reaction to atenolol

A

fatigue

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41
Q

what is the generic name for Uloric

A

febuxostat

42
Q

What is the generic name of Advair Diskus

A

fluticasone/salmeterol

43
Q

what is the brand name of dexmethylphenidate

A

Focalin

44
Q

Which of the following is a major adverse drug reaction from eszopiclone

A

headache

45
Q

which of the following is an FDA approved indication for labetalol

A

hypertension

46
Q

which of the following is a major adverse drug reaction to valsartan

A

increased BUN

47
Q

what is a major adverse drug reaction of minocycline

A

increased intracranial pressure

48
Q

which of the following is a major adverse drug reaction to valacyclovir

A

increased LFTs

49
Q

concurrent use of gemfibrozil and glyburide should be avoided due to

A

increased risk of hypoglycemia

50
Q

what is the mechanism of action for spironolactone

A

inhibition of aldosterone

51
Q

what is the MOA for amoxicillin

A

inhibition of bacterial cell wall synthesis

52
Q

what is the mechanism of action for nifedipine

A

inhibition of calcium influx

53
Q

what is the mechanism of action of Plavix

A

inhibition of glycoprotein IIb/IIIa complex

54
Q

what is the MOA of Oseltamivir

A

inhibition of influenza virus neuraminidase

55
Q

what is the MOA for fidazomicin

A

inhibits bacterial RNA polymerases

56
Q

which of the following medications has a mechanism of action of enhancing the postsynaptic effect of GABA

A

lorazepam

57
Q

what is an FDA approved indication for Ceftin

A

Lyme disease

58
Q

Which of the following is an FDA approved indication for propranolol

A

migraines

59
Q

which of the following medications has the mechanism of action of increasing noradrenergic activity and enhancing serotonergic activity

A

mirtazapine

60
Q

Which of the following is a major adverse drug reaction to amoxicillin/clavulanate

A

nausea and diarrhea

61
Q

what is the generic name of Alinia

A

nitazoxanide

62
Q

does fluconazole require hepatic dose adjustment

A

no

63
Q

does clindamycin require dosage adjustment for hepatic impairment

A

no

64
Q

which of the following is a TCA

A

nortriptyline

65
Q

what is an FDA approved indication for ropinirole

A

Parkinsons disease

66
Q

in which pharmacological class is ticagrelor

A

platelet aggregation inhibitor

67
Q

what is the mechanism of action for omega-3 acids

A

PPAR alpha activator

68
Q

which one of the following is the generic name for Lyrica

A

pregabalin

69
Q

what is the mechanism of action of doxepin

A

prevents the deactivation of norepinephrine

70
Q

which of the following is a major adverse drug reaction to escitalopram

A

prolonged QTc interval

71
Q

which of the following inhibits the catalytic activity of integrase HIV-1 integrase thus preventing the integration of the viral DNA into the host strand

A

Raltegravir

72
Q

What is a major adverse reaction to lovastatin

A

rhabdomyolysis

73
Q

what is a major adverse reaction to fenofibrate

A

rhabdomyolysis

74
Q

What is the brand name for edoxaban

A

Savaysa

75
Q

What is the name brand for maraviroc

A

Selzentry

76
Q

What is the generic name for Zoloft

A

Sertraline

77
Q

What is an FDA approved indication for moxifloxacin

A

skin and soft tissue infections

78
Q

What is a major adverse drug reaction to cephalexin

A

Stevens-Johnsons Syndrome

79
Q

what is a major adverse drug reaction to sofosbuvir

A

suicidality

80
Q

the brand name of budesonide/formoterol is

A

Symbicort

81
Q

What is the major adverse reaction to Crestor

A

tendon rupture

82
Q

what is the pharmacological class of doxycycline

A

tetracycline

83
Q

what is the pharmacological class of chlorthalidone

A

thiazide

84
Q

what is a major adverse reaction to Entecavir

A

thrombocytopenia

85
Q

What is an FDA approved indication of terbinafine

A

Tinea capitis

86
Q

What is an FDA indication for topical ketoconazole

A

tinea corporis

87
Q

which of the following is approved for depression

A

Trazadone

88
Q

Cordarone has the potential to increase the adverse effects of CYP3A4 and/or PGP substrates (true or false)

A

True

89
Q

What is the major adverse drug reaction of nitrofurantoin

A

urine discoloration

90
Q

Tolvaptan belongs in which pharmacological class

A

vasopressin antagonist

91
Q

which of the following drugs is considered an SNRI

A

venlafaxine

92
Q

what is the brand name for colesevelam

A

Welchol

93
Q

which of the following is a major adverse reaction to temazepam

A

worsening depression

94
Q

What is the brand name for levalbuterol

A

Xopenex

95
Q

Does apixaban require dosage adjustment for renal insufficiency when used for A-fib?

A

yes

96
Q

Does trimethoprim/sulfamethoxazole require dosage adjustment for renal dysfunction

A

yes

97
Q

What is the brand name for bisoprolol

A

Zebeta

98
Q

What is the brand name for lisinopril

A

Zestril

99
Q

Which macrolide antibiotic could be used to avoid potential drug-drug interactions mediated by CYP3A4 inhibition

A

Zithromax

100
Q

What is the brand name for Imiquimod

A

Zyclara

Top 300 Fall P3 (1 decks)

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