top 300 Flashcards

1
Q

What is the pharmacological class of quinapril

A

ACE inhibitor

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2
Q

Which of the following is an FDA approved indication for atomoxetine

A

ADHD

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3
Q

What is an FDA approved indication for clonidine

A

ADHD

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4
Q

Which of the following is an FDA aproved indication for digoxin

A

A-fib

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5
Q

What is the major adverse reaction to hydralazine

A

agranulocytosis

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6
Q

The brand name of albendazole is

A

Albenza

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7
Q

Which is FDA indicated for the treatment of gout

A

allopurinol

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8
Q

Which of the following is the brand name of Zolpidem

A

Ambien

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9
Q

What is a major adverse reaction to ramipril

A

angioedema

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10
Q

what is a major adverse drug reaction to benazepril

A

angioedema

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11
Q

what is the pharmacological class for Atacand

A

Angiotensin Receptor Blocker

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12
Q

Which of the following is the MOA for Telmesartan

A

Antagonizes angiotensin II receptors

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13
Q

What is the pharmacological class of Ranexa

A

antianginal agent

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14
Q

What is the pharmacological class of isosorbide mononitrate

A

antianginal agent

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15
Q

the pharmacological class of benzonatate is

A

antitussive

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16
Q

the pharmacological class of acyclovir is

A

antiviral

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17
Q

which of the following is an adverse effect of modafinil

A

anxiety

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18
Q

what is a major adverse drug reaction to rifaximin

A

ascites

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19
Q

what of the following drugs is a protease inhibitor

A

Atazanavir

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20
Q

What is the brand name for irbesartan

A

Avapro

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21
Q

what is the brand name for olmesartan

A

Benicar

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22
Q

Which of the following is an FDA approved indication for doxazosin

A

BPH

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23
Q

Which of the following is an FDA approved indication for terazosin

A

BPH

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24
Q

What is the pharmacological class of metoprolol

A

Beta-blocker

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25
What is the MOA for chlorhexidine
binds to the negatively charged cell wall and extra microbial complexes
26
What is the pharmacological class of diltiazem
CCB
27
What is the pharmacological class of ezetimibe
cholesterol absorption inhibitor
28
St John's wort is a known inducer of CYP3A4 and Pgp; if coadministered with Xarelto, a patient might be at increased risk of treatment failure due to
clotting
29
St John's wort is a known inducer of CYP3A4 and Pgp; if coadministered with dabigatran, a patient might be at increased risk of treatment failure due to
clotting
30
which of the following would be expected to increase the risk of bleeding in a patient stabilized on warfarin
co-administration of a CYP2C9 inhibitor
31
the pharmacological class of budesonide is
corticosteroid
32
which of the following has the potential to increase the metabolism of Sustiva thereby reducing its therapeutic effectiveness
A CYP3A4 inducer
33
Which of the following is an FDA approved indication for amitriptyline
depression
34
what is a major AE to dipyridamole
dizziness
35
what effect would fluoxetine have on carvedilol AUC and clearance
due to inhibition of CYP2D6, carvedilol clearance will decrease and the AUC will increase
36
Which of the following is the brand name of triamterene/HCTZ
Dyazide
37
which of the following is an approved indication for hydrochlorothiazide
edema
38
what is the FDA indication for phenobarbital
epilepsy
39
what is a major adverse drug reaction to carvedilol
erectile dysfunction
40
what is a major adverse drug reaction to atenolol
fatigue
41
what is the generic name for Uloric
febuxostat
42
What is the generic name of Advair Diskus
fluticasone/salmeterol
43
what is the brand name of dexmethylphenidate
Focalin
44
Which of the following is a major adverse drug reaction from eszopiclone
headache
45
which of the following is an FDA approved indication for labetalol
hypertension
46
which of the following is a major adverse drug reaction to valsartan
increased BUN
47
what is a major adverse drug reaction of minocycline
increased intracranial pressure
48
which of the following is a major adverse drug reaction to valacyclovir
increased LFTs
49
concurrent use of gemfibrozil and glyburide should be avoided due to
increased risk of hypoglycemia
50
what is the mechanism of action for spironolactone
inhibition of aldosterone
51
what is the MOA for amoxicillin
inhibition of bacterial cell wall synthesis
52
what is the mechanism of action for nifedipine
inhibition of calcium influx
53
what is the mechanism of action of Plavix
inhibition of glycoprotein IIb/IIIa complex
54
what is the MOA of Oseltamivir
inhibition of influenza virus neuraminidase
55
what is the MOA for fidazomicin
inhibits bacterial RNA polymerases
56
which of the following medications has a mechanism of action of enhancing the postsynaptic effect of GABA
lorazepam
57
what is an FDA approved indication for Ceftin
Lyme disease
58
Which of the following is an FDA approved indication for propranolol
migraines
59
which of the following medications has the mechanism of action of increasing noradrenergic activity and enhancing serotonergic activity
mirtazapine
60
Which of the following is a major adverse drug reaction to amoxicillin/clavulanate
nausea and diarrhea
61
what is the generic name of Alinia
nitazoxanide
62
does fluconazole require hepatic dose adjustment
no
63
does clindamycin require dosage adjustment for hepatic impairment
no
64
which of the following is a TCA
nortriptyline
65
what is an FDA approved indication for ropinirole
Parkinsons disease
66
in which pharmacological class is ticagrelor
platelet aggregation inhibitor
67
what is the mechanism of action for omega-3 acids
PPAR alpha activator
68
which one of the following is the generic name for Lyrica
pregabalin
69
what is the mechanism of action of doxepin
prevents the deactivation of norepinephrine
70
which of the following is a major adverse drug reaction to escitalopram
prolonged QTc interval
71
which of the following inhibits the catalytic activity of integrase HIV-1 integrase thus preventing the integration of the viral DNA into the host strand
Raltegravir
72
What is a major adverse reaction to lovastatin
rhabdomyolysis
73
what is a major adverse reaction to fenofibrate
rhabdomyolysis
74
What is the brand name for edoxaban
Savaysa
75
What is the name brand for maraviroc
Selzentry
76
What is the generic name for Zoloft
Sertraline
77
What is an FDA approved indication for moxifloxacin
skin and soft tissue infections
78
What is a major adverse drug reaction to cephalexin
Stevens-Johnsons Syndrome
79
what is a major adverse drug reaction to sofosbuvir
suicidality
80
the brand name of budesonide/formoterol is
Symbicort
81
What is the major adverse reaction to Crestor
tendon rupture
82
what is the pharmacological class of doxycycline
tetracycline
83
what is the pharmacological class of chlorthalidone
thiazide
84
what is a major adverse reaction to Entecavir
thrombocytopenia
85
What is an FDA approved indication of terbinafine
Tinea capitis
86
What is an FDA indication for topical ketoconazole
tinea corporis
87
which of the following is approved for depression
Trazadone
88
Cordarone has the potential to increase the adverse effects of CYP3A4 and/or PGP substrates (true or false)
True
89
What is the major adverse drug reaction of nitrofurantoin
urine discoloration
90
Tolvaptan belongs in which pharmacological class
vasopressin antagonist
91
which of the following drugs is considered an SNRI
venlafaxine
92
what is the brand name for colesevelam
Welchol
93
which of the following is a major adverse reaction to temazepam
worsening depression
94
What is the brand name for levalbuterol
Xopenex
95
Does apixaban require dosage adjustment for renal insufficiency when used for A-fib?
yes
96
Does trimethoprim/sulfamethoxazole require dosage adjustment for renal dysfunction
yes
97
What is the brand name for bisoprolol
Zebeta
98
What is the brand name for lisinopril
Zestril
99
Which macrolide antibiotic could be used to avoid potential drug-drug interactions mediated by CYP3A4 inhibition
Zithromax
100
What is the brand name for Imiquimod
Zyclara