Top 300 Flashcards
Escitalopram
Lexapro
Escitalopram enantiomer?
S-enantiomer of Citalopram
Class of Escitalopram?
Antidepressant - SSRI
Metabolism of Escitalopram?
CYP3A4 and CYP2C19
DIs of Escitalopram?
MAOIs (neuroleptic malignant syndrome risk - don’t use within 14 days of starting Escitalopram)
Precaution of antidepressants?
Increase the risk of suicidal thoughts and actions in some children and teenagers
Pregnancy category of Escitalopram?
C
AE of Escitalopram?
Nausea, ejaculation disorder, insomnia, diarrhea, somnolence
Counseling points of Escitalopram?
Avoid OH, consult MD before starting OTC, don’t stop abruptly, may take 2 weeks of therapy to see improvement
Tenormin
Atenolol
Class of Tenormin?
Antihypertensive
MOA of Atenolol?
Cardioselective B1
PDs of Atenolol?
Decreased HR and CO, Decreased BP, # isoproterenol tachycardia, decreased reflex orthostatic tachycardia
DIs of Atenolol?
Decreases effects of Clonidine. Toxic effects increased by Verapamil.
CI of Atenolol?
Sinus bradycardia, heart block > 1st degree, cardiogenic shock, and overt cardiac failure.